SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zvy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN
(Camelus
dromedarius) 		3 / 3 TRP A  36
ALA A  50
VAL A  48
 None
 0.98A 1bdwA-1zvyA:
undetectable
1bdwB-1zvyA:
undetectable		 1bdwA-1zvyA:
8.99
1bdwB-1zvyA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN
(Camelus
dromedarius) 		4 / 6 LEU A 109
LYS A  65
GLN A  72
ILE A  70
 None
 1.15A 2jn3A-1zvyA:
undetectable		 2jn3A-1zvyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN
(Camelus
dromedarius) 		3 / 3 TYR A  33
THR A  35
THR A  99
 None
 0.77A 5aoxB-1zvyA:
undetectable		 5aoxB-1zvyA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN
(Camelus
dromedarius) 		3 / 3 TYR A  33
THR A  35
THR A  99
 None
 0.68A 5aoxE-1zvyA:
undetectable		 5aoxE-1zvyA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN
(Camelus
dromedarius) 		3 / 3 SER A  88
LEU A  81
MET A  83
 None
 0.86A 5ikrB-1zvyA:
undetectable		 5ikrB-1zvyA:
11.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 1zvy IMMUNOGLOBULIN HEAVY
CHAIN ANTIBODY
VARIABLE DOMAIN
(Camelus
dromedarius) 		3 / 3 TYR A  60
GLY A  66
THR A  69
 None
 0.17A 6cjkB-1zvyA:
19.6		 6cjkB-1zvyA:
32.30