SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zwt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.88A 1a7yB-1zwtA:
undetectable		 1a7yB-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.92A 1dscC-1zwtA:
undetectable		 1dscC-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A 136
THR A  99
PRO A 137
 None
 0.84A 1dscC-1zwtA:
undetectable		 1dscC-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  41
LEU A  38
VAL A  71
 None
 0.65A 1mz9E-1zwtA:
undetectable		 1mz9E-1zwtA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.84A 1unjR-1zwtA:
undetectable		 1unjR-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A 136
THR A  99
PRO A 137
 None
 0.83A 1unjW-1zwtA:
undetectable		 1unjW-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.86A 1unjX-1zwtA:
undetectable		 1unjX-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.87A 1unmE-1zwtA:
undetectable		 1unmE-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.91A 316dC-1zwtA:
undetectable		 316dC-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		4 / 8 SER A  34
GLY A 108
ILE A 119
ALA A 130
 None
 0.86A 3aodA-1zwtA:
undetectable		 3aodA-1zwtA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		5 / 11 ALA A 130
PHE A 122
ASN A 117
GLY A 115
THR A  62
 None
 1.19A 3rukD-1zwtA:
undetectable		 3rukD-1zwtA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  99
PRO A 137
THR A 136
 None
 0.88A 4hivD-1zwtA:
undetectable		 4hivD-1zwtA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		3 / 3 THR A  57
ASN A  58
SER A 149
 None
 0.76A 4tvtA-1zwtA:
undetectable		 4tvtA-1zwtA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA302_0
(AMIDASE)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		5 / 9 GLU A 139
LYS A 131
TYR A 155
ALA A 134
LEU A 100
 None
 1.27A 5ny7A-1zwtA:
0.0		 5ny7A-1zwtA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 1zwt MAJOR STRUCTURAL
SUBUNIT OF
BUNDLE-FORMING PILUS
(Escherichia
coli) 		5 / 12 ILE A  42
SER A  40
LEU A  84
ASN A  70
ASP A  39
 None
 1.37A 6dwnB-1zwtA:
undetectable		 6dwnB-1zwtA:
18.71