SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zwx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
PHE A 167
PHE A 153
THR A 186
LEU A 230
 None
 1.23A 1a8uA-1zwxA:
undetectable		 1a8uA-1zwxA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1c9sA-1zwxA:
undetectable
1c9sK-1zwxA:
undetectable		 1c9sA-1zwxA:
13.62
1c9sK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1c9sA-1zwxA:
undetectable
1c9sB-1zwxA:
undetectable		 1c9sA-1zwxA:
13.62
1c9sB-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1c9sB-1zwxA:
undetectable
1c9sC-1zwxA:
undetectable		 1c9sB-1zwxA:
13.62
1c9sC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1c9sC-1zwxA:
undetectable
1c9sD-1zwxA:
undetectable		 1c9sC-1zwxA:
13.62
1c9sD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1c9sD-1zwxA:
undetectable
1c9sE-1zwxA:
undetectable		 1c9sD-1zwxA:
13.62
1c9sE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1c9sE-1zwxA:
undetectable
1c9sF-1zwxA:
undetectable		 1c9sE-1zwxA:
13.62
1c9sF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1c9sF-1zwxA:
undetectable
1c9sG-1zwxA:
undetectable		 1c9sF-1zwxA:
13.62
1c9sG-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1c9sG-1zwxA:
undetectable
1c9sH-1zwxA:
undetectable		 1c9sG-1zwxA:
13.62
1c9sH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 1c9sH-1zwxA:
undetectable
1c9sI-1zwxA:
undetectable		 1c9sH-1zwxA:
13.62
1c9sI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1c9sJ-1zwxA:
undetectable
1c9sK-1zwxA:
undetectable		 1c9sJ-1zwxA:
13.62
1c9sK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1c9sL-1zwxA:
undetectable
1c9sM-1zwxA:
undetectable		 1c9sL-1zwxA:
13.62
1c9sM-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 1c9sM-1zwxA:
undetectable
1c9sN-1zwxA:
undetectable		 1c9sM-1zwxA:
13.62
1c9sN-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 1c9sN-1zwxA:
0.0
1c9sO-1zwxA:
0.0		 1c9sN-1zwxA:
13.62
1c9sO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1c9sO-1zwxA:
undetectable
1c9sP-1zwxA:
undetectable		 1c9sO-1zwxA:
13.62
1c9sP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 1c9sQ-1zwxA:
undetectable
1c9sR-1zwxA:
undetectable		 1c9sQ-1zwxA:
13.62
1c9sR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1c9sS-1zwxA:
undetectable
1c9sT-1zwxA:
undetectable		 1c9sS-1zwxA:
13.62
1c9sT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1gtfA-1zwxA:
undetectable
1gtfK-1zwxA:
undetectable		 1gtfA-1zwxA:
13.62
1gtfK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1gtfA-1zwxA:
undetectable
1gtfB-1zwxA:
undetectable		 1gtfA-1zwxA:
13.62
1gtfB-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1gtfB-1zwxA:
undetectable
1gtfC-1zwxA:
undetectable		 1gtfB-1zwxA:
13.62
1gtfC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 1gtfC-1zwxA:
undetectable
1gtfD-1zwxA:
undetectable		 1gtfC-1zwxA:
13.62
1gtfD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1gtfE-1zwxA:
undetectable
1gtfF-1zwxA:
undetectable		 1gtfE-1zwxA:
13.62
1gtfF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1gtfF-1zwxA:
undetectable
1gtfG-1zwxA:
undetectable		 1gtfF-1zwxA:
13.62
1gtfG-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1gtfG-1zwxA:
undetectable
1gtfH-1zwxA:
undetectable		 1gtfG-1zwxA:
13.62
1gtfH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 1gtfH-1zwxA:
undetectable
1gtfI-1zwxA:
undetectable		 1gtfH-1zwxA:
13.62
1gtfI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1gtfI-1zwxA:
undetectable
1gtfJ-1zwxA:
undetectable		 1gtfI-1zwxA:
13.62
1gtfJ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 1gtfO-1zwxA:
undetectable
1gtfP-1zwxA:
undetectable		 1gtfO-1zwxA:
13.62
1gtfP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 1gtfO-1zwxA:
undetectable
1gtfP-1zwxA:
undetectable		 1gtfO-1zwxA:
13.62
1gtfP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 1gtfP-1zwxA:
undetectable
1gtfQ-1zwxA:
undetectable		 1gtfP-1zwxA:
13.62
1gtfQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 1gtfR-1zwxA:
undetectable
1gtfS-1zwxA:
undetectable		 1gtfR-1zwxA:
13.62
1gtfS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 1gtfT-1zwxA:
undetectable
1gtfU-1zwxA:
undetectable		 1gtfT-1zwxA:
13.62
1gtfU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 1gtfU-1zwxA:
undetectable
1gtfV-1zwxA:
undetectable		 1gtfU-1zwxA:
13.62
1gtfV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 1gtfL-1zwxA:
undetectable
1gtfV-1zwxA:
undetectable		 1gtfL-1zwxA:
13.62
1gtfV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 1gtfL-1zwxA:
undetectable
1gtfV-1zwxA:
undetectable		 1gtfL-1zwxA:
13.62
1gtfV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 8 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.26A 1gtnA-1zwxA:
undetectable
1gtnB-1zwxA:
undetectable		 1gtnA-1zwxA:
13.62
1gtnB-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 1gtnM-1zwxA:
undetectable
1gtnN-1zwxA:
undetectable		 1gtnM-1zwxA:
13.62
1gtnN-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 1gtnN-1zwxA:
undetectable
1gtnO-1zwxA:
undetectable		 1gtnN-1zwxA:
13.62
1gtnO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 1gtnR-1zwxA:
undetectable
1gtnS-1zwxA:
undetectable		 1gtnR-1zwxA:
13.62
1gtnS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.15A 1gtnR-1zwxA:
undetectable
1gtnS-1zwxA:
undetectable		 1gtnR-1zwxA:
13.62
1gtnS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1gtnU-1zwxA:
undetectable
1gtnV-1zwxA:
undetectable		 1gtnU-1zwxA:
13.62
1gtnV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 ASN A  87
THR A 184
LEU A 230
VAL A 328
PHE A 285
 None
 1.32A 1tw4A-1zwxA:
undetectable		 1tw4A-1zwxA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1utdA-1zwxA:
undetectable
1utdB-1zwxA:
undetectable		 1utdA-1zwxA:
13.62
1utdB-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 8 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1utdB-1zwxA:
undetectable
1utdC-1zwxA:
undetectable		 1utdB-1zwxA:
13.62
1utdC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1utdC-1zwxA:
undetectable
1utdD-1zwxA:
undetectable		 1utdC-1zwxA:
13.62
1utdD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1utdD-1zwxA:
undetectable
1utdE-1zwxA:
undetectable		 1utdD-1zwxA:
13.62
1utdE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 8 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.26A 1utdF-1zwxA:
undetectable
1utdG-1zwxA:
undetectable		 1utdF-1zwxA:
13.62
1utdG-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 1utdG-1zwxA:
undetectable
1utdH-1zwxA:
undetectable		 1utdG-1zwxA:
13.62
1utdH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 8 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 1utdJ-1zwxA:
undetectable
1utdK-1zwxA:
undetectable		 1utdJ-1zwxA:
13.62
1utdK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 1utdA-1zwxA:
undetectable
1utdK-1zwxA:
undetectable		 1utdA-1zwxA:
13.62
1utdK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 1utdM-1zwxA:
undetectable
1utdN-1zwxA:
undetectable		 1utdM-1zwxA:
13.62
1utdN-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 1utdN-1zwxA:
undetectable
1utdO-1zwxA:
undetectable		 1utdN-1zwxA:
13.62
1utdO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1utdQ-1zwxA:
undetectable
1utdR-1zwxA:
undetectable		 1utdQ-1zwxA:
13.62
1utdR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1utdR-1zwxA:
undetectable
1utdS-1zwxA:
undetectable		 1utdR-1zwxA:
13.62
1utdS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 1utdT-1zwxA:
undetectable
1utdU-1zwxA:
undetectable		 1utdT-1zwxA:
13.62
1utdU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 1utdU-1zwxA:
undetectable
1utdV-1zwxA:
undetectable		 1utdU-1zwxA:
13.62
1utdV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		3 / 3 THR A 186
GLU A 204
HIS A 151
 None
 0.72A 1xwfA-1zwxA:
undetectable		 1xwfA-1zwxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		3 / 3 THR A 186
GLU A 204
HIS A 151
 None
 0.74A 1xwfB-1zwxA:
undetectable		 1xwfB-1zwxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		3 / 3 THR A 186
GLU A 204
HIS A 151
 None
 0.77A 1xwfC-1zwxA:
undetectable		 1xwfC-1zwxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		3 / 3 THR A 186
GLU A 204
HIS A 151
 None
 0.73A 1xwfD-1zwxA:
undetectable		 1xwfD-1zwxA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 6 GLU A  88
TYR A  53
GLN A 187
ASP A 282
 PO4  A 401 (-3.2A)
None
None
None
 1.41A 2cl5B-1zwxA:
2.0		 2cl5B-1zwxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 6 THR A 186
MET A 242
PHE A 285
ILE A 226
 None
 1.23A 2w98B-1zwxA:
undetectable		 2w98B-1zwxA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 6 GLU A  88
TYR A  53
GLN A 187
ASP A 282
 PO4  A 401 (-3.2A)
None
None
None
 1.39A 2zvjA-1zwxA:
undetectable		 2zvjA-1zwxA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 136
GLN A 150
THR A 110
PHE A 167
GLY A 183
 None
 1.28A 3ablA-1zwxA:
undetectable
3ablB-1zwxA:
0.0
3ablT-1zwxA:
0.0		 3ablA-1zwxA:
19.15
3ablB-1zwxA:
20.85
3ablT-1zwxA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 PRO A 111
ILE A 113
SER A 116
GLY A 114
 None
 0.94A 3lslA-1zwxA:
undetectable
3lslD-1zwxA:
undetectable		 3lslA-1zwxA:
20.13
3lslD-1zwxA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 5 PHE A 285
ILE A  47
ASN A 233
PHE A 225
 None
 1.35A 3octA-1zwxA:
undetectable		 3octA-1zwxA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ILE A 218
TYR A 169
HIS A 151
VAL A 137
 None
 1.07A 4a97D-1zwxA:
undetectable		 4a97D-1zwxA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.19A 4fevD-1zwxA:
undetectable		 4fevD-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.19A 4fevF-1zwxA:
undetectable		 4fevF-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.20A 4fewD-1zwxA:
undetectable		 4fewD-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.20A 4fewF-1zwxA:
undetectable		 4fewF-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.17A 4gkhF-1zwxA:
undetectable		 4gkhF-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.20A 4gkhG-1zwxA:
undetectable		 4gkhG-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 ASP A 190
ASN A 231
GLU A 279
GLU A  88
 None
PO4  A 401 ( 4.3A)
None
PO4  A 401 (-3.2A)
 1.18A 4gkiA-1zwxA:
undetectable		 4gkiA-1zwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 ASN A 164
ALA A 131
SER A 163
ARG A 161
 None
 1.18A 4ijiF-1zwxA:
undetectable		 4ijiF-1zwxA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 ALA A 168
ILE A  85
ILE A 224
VAL A  83
VAL A 139
 None
 0.94A 4j5jB-1zwxA:
undetectable		 4j5jB-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 LEU A 102
ILE A 172
ILE A 145
VAL A 170
 None
 0.82A 4ojbA-1zwxA:
undetectable		 4ojbA-1zwxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ALA A  73
ASP A  91
ARG A  57
GLY A  64
 None
 0.79A 5bs8A-1zwxA:
undetectable
5bs8C-1zwxA:
undetectable
5bs8D-1zwxA:
undetectable		 5bs8A-1zwxA:
18.54
5bs8C-1zwxA:
18.54
5bs8D-1zwxA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ALA A  73
ASP A  91
ARG A  57
GLY A  64
 None
 0.79A 5bs8A-1zwxA:
undetectable
5bs8B-1zwxA:
undetectable
5bs8C-1zwxA:
undetectable		 5bs8A-1zwxA:
18.54
5bs8B-1zwxA:
18.27
5bs8C-1zwxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ALA A  73
ASP A  91
ARG A  57
GLY A  64
 None
 0.78A 5btdA-1zwxA:
undetectable
5btdB-1zwxA:
undetectable
5btdC-1zwxA:
undetectable		 5btdA-1zwxA:
18.54
5btdB-1zwxA:
18.27
5btdC-1zwxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ALA A  73
ASP A  91
ARG A  57
GLY A  64
 None
 0.75A 5btdA-1zwxA:
undetectable
5btdC-1zwxA:
undetectable
5btdD-1zwxA:
undetectable		 5btdA-1zwxA:
18.54
5btdC-1zwxA:
18.54
5btdD-1zwxA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 7 ALA A  73
ASP A  91
ARG A  57
GLY A  64
 None
 0.81A 5btgA-1zwxA:
undetectable
5btgC-1zwxA:
undetectable
5btgD-1zwxA:
undetectable		 5btgA-1zwxA:
18.54
5btgC-1zwxA:
18.54
5btgD-1zwxA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 12 TYR A 273
HIS A 185
ASP A 229
ASN A 231
HIS A 325
 None
None
None
PO4  A 401 ( 4.3A)
PO4  A 401 (-3.8A)
 1.02A 5dv4A-1zwxA:
19.7		 5dv4A-1zwxA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeuA-1zwxA:
undetectable
5eeuB-1zwxA:
undetectable		 5eeuA-1zwxA:
13.62
5eeuB-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 5eeuB-1zwxA:
undetectable
5eeuC-1zwxA:
undetectable		 5eeuB-1zwxA:
13.62
5eeuC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeuC-1zwxA:
undetectable
5eeuD-1zwxA:
undetectable		 5eeuC-1zwxA:
13.62
5eeuD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eeuD-1zwxA:
undetectable
5eeuE-1zwxA:
undetectable		 5eeuD-1zwxA:
13.62
5eeuE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeuE-1zwxA:
undetectable
5eeuF-1zwxA:
undetectable		 5eeuE-1zwxA:
13.62
5eeuF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeuG-1zwxA:
undetectable
5eeuH-1zwxA:
undetectable		 5eeuG-1zwxA:
13.62
5eeuH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eeuH-1zwxA:
undetectable
5eeuI-1zwxA:
undetectable		 5eeuH-1zwxA:
13.62
5eeuI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eeuJ-1zwxA:
undetectable
5eeuK-1zwxA:
undetectable		 5eeuJ-1zwxA:
13.62
5eeuK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 5eeuA-1zwxA:
undetectable
5eeuK-1zwxA:
undetectable		 5eeuA-1zwxA:
13.62
5eeuK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eeuN-1zwxA:
undetectable
5eeuO-1zwxA:
undetectable		 5eeuN-1zwxA:
13.62
5eeuO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eeuO-1zwxA:
undetectable
5eeuP-1zwxA:
undetectable		 5eeuO-1zwxA:
13.62
5eeuP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5eeuP-1zwxA:
undetectable
5eeuQ-1zwxA:
undetectable		 5eeuP-1zwxA:
13.62
5eeuQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eeuP-1zwxA:
undetectable
5eeuQ-1zwxA:
undetectable		 5eeuP-1zwxA:
13.62
5eeuQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 5eeuQ-1zwxA:
undetectable
5eeuR-1zwxA:
undetectable		 5eeuQ-1zwxA:
13.62
5eeuR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eeuR-1zwxA:
undetectable
5eeuS-1zwxA:
undetectable		 5eeuR-1zwxA:
13.62
5eeuS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eeuS-1zwxA:
undetectable
5eeuT-1zwxA:
undetectable		 5eeuS-1zwxA:
13.62
5eeuT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eeuT-1zwxA:
undetectable
5eeuU-1zwxA:
undetectable		 5eeuT-1zwxA:
13.62
5eeuU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5eeuU-1zwxA:
undetectable
5eeuV-1zwxA:
undetectable		 5eeuU-1zwxA:
13.62
5eeuV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eeuU-1zwxA:
undetectable
5eeuV-1zwxA:
undetectable		 5eeuU-1zwxA:
13.62
5eeuV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eevB-1zwxA:
undetectable
5eevC-1zwxA:
undetectable		 5eevB-1zwxA:
13.62
5eevC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eevC-1zwxA:
undetectable
5eevD-1zwxA:
undetectable		 5eevC-1zwxA:
13.62
5eevD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eevD-1zwxA:
undetectable
5eevE-1zwxA:
undetectable		 5eevD-1zwxA:
13.62
5eevE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eevE-1zwxA:
undetectable
5eevF-1zwxA:
undetectable		 5eevE-1zwxA:
13.62
5eevF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eevG-1zwxA:
undetectable
5eevH-1zwxA:
undetectable		 5eevG-1zwxA:
13.62
5eevH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eevH-1zwxA:
undetectable
5eevI-1zwxA:
undetectable		 5eevH-1zwxA:
13.62
5eevI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eevJ-1zwxA:
undetectable
5eevK-1zwxA:
undetectable		 5eevJ-1zwxA:
13.62
5eevK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 5eevA-1zwxA:
undetectable
5eevK-1zwxA:
undetectable		 5eevA-1zwxA:
13.62
5eevK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eevN-1zwxA:
undetectable
5eevO-1zwxA:
undetectable		 5eevN-1zwxA:
13.62
5eevO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eevO-1zwxA:
undetectable
5eevP-1zwxA:
undetectable		 5eevO-1zwxA:
13.62
5eevP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5eevP-1zwxA:
undetectable
5eevQ-1zwxA:
undetectable		 5eevP-1zwxA:
13.62
5eevQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eevP-1zwxA:
undetectable
5eevQ-1zwxA:
undetectable		 5eevP-1zwxA:
13.62
5eevQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eevQ-1zwxA:
undetectable
5eevR-1zwxA:
undetectable		 5eevQ-1zwxA:
13.62
5eevR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eevR-1zwxA:
undetectable
5eevS-1zwxA:
undetectable		 5eevR-1zwxA:
13.62
5eevS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eevS-1zwxA:
undetectable
5eevT-1zwxA:
undetectable		 5eevS-1zwxA:
13.62
5eevT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eevT-1zwxA:
undetectable
5eevU-1zwxA:
undetectable		 5eevT-1zwxA:
13.62
5eevU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5eevU-1zwxA:
undetectable
5eevV-1zwxA:
undetectable		 5eevU-1zwxA:
13.62
5eevV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eevU-1zwxA:
undetectable
5eevV-1zwxA:
undetectable		 5eevU-1zwxA:
13.62
5eevV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 5eewB-1zwxA:
undetectable
5eewC-1zwxA:
undetectable		 5eewB-1zwxA:
13.62
5eewC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eewC-1zwxA:
undetectable
5eewD-1zwxA:
undetectable		 5eewC-1zwxA:
13.62
5eewD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eewD-1zwxA:
undetectable
5eewE-1zwxA:
undetectable		 5eewD-1zwxA:
13.62
5eewE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eewE-1zwxA:
undetectable
5eewF-1zwxA:
undetectable		 5eewE-1zwxA:
13.62
5eewF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eewG-1zwxA:
undetectable
5eewH-1zwxA:
undetectable		 5eewG-1zwxA:
13.62
5eewH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eewH-1zwxA:
undetectable
5eewI-1zwxA:
undetectable		 5eewH-1zwxA:
13.62
5eewI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eewJ-1zwxA:
undetectable
5eewK-1zwxA:
undetectable		 5eewJ-1zwxA:
13.62
5eewK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.26A 5eewA-1zwxA:
undetectable
5eewK-1zwxA:
undetectable		 5eewA-1zwxA:
13.62
5eewK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eewN-1zwxA:
undetectable
5eewO-1zwxA:
undetectable		 5eewN-1zwxA:
13.62
5eewO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eewO-1zwxA:
undetectable
5eewP-1zwxA:
undetectable		 5eewO-1zwxA:
13.62
5eewP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5eewP-1zwxA:
undetectable
5eewQ-1zwxA:
undetectable		 5eewP-1zwxA:
13.62
5eewQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eewP-1zwxA:
undetectable
5eewQ-1zwxA:
undetectable		 5eewP-1zwxA:
13.62
5eewQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eewQ-1zwxA:
undetectable
5eewR-1zwxA:
undetectable		 5eewQ-1zwxA:
13.62
5eewR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eewR-1zwxA:
undetectable
5eewS-1zwxA:
undetectable		 5eewR-1zwxA:
13.62
5eewS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eewS-1zwxA:
undetectable
5eewT-1zwxA:
undetectable		 5eewS-1zwxA:
13.62
5eewT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eewT-1zwxA:
undetectable
5eewU-1zwxA:
undetectable		 5eewT-1zwxA:
13.62
5eewU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5eewU-1zwxA:
undetectable
5eewV-1zwxA:
undetectable		 5eewU-1zwxA:
13.62
5eewV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eewU-1zwxA:
undetectable
5eewV-1zwxA:
undetectable		 5eewU-1zwxA:
13.62
5eewV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eexB-1zwxA:
undetectable
5eexC-1zwxA:
undetectable		 5eexB-1zwxA:
13.62
5eexC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eexC-1zwxA:
undetectable
5eexD-1zwxA:
undetectable		 5eexC-1zwxA:
13.62
5eexD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eexD-1zwxA:
undetectable
5eexE-1zwxA:
undetectable		 5eexD-1zwxA:
13.62
5eexE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eexE-1zwxA:
undetectable
5eexF-1zwxA:
undetectable		 5eexE-1zwxA:
13.62
5eexF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eexG-1zwxA:
undetectable
5eexH-1zwxA:
undetectable		 5eexG-1zwxA:
13.62
5eexH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eexH-1zwxA:
undetectable
5eexI-1zwxA:
undetectable		 5eexH-1zwxA:
13.62
5eexI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eexI-1zwxA:
undetectable
5eexJ-1zwxA:
undetectable		 5eexI-1zwxA:
13.62
5eexJ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eexJ-1zwxA:
undetectable
5eexK-1zwxA:
undetectable		 5eexJ-1zwxA:
13.62
5eexK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.26A 5eexA-1zwxA:
undetectable
5eexK-1zwxA:
undetectable		 5eexA-1zwxA:
13.62
5eexK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eexN-1zwxA:
undetectable
5eexO-1zwxA:
undetectable		 5eexN-1zwxA:
13.62
5eexO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eexO-1zwxA:
undetectable
5eexP-1zwxA:
undetectable		 5eexO-1zwxA:
13.62
5eexP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5eexP-1zwxA:
undetectable
5eexQ-1zwxA:
undetectable		 5eexP-1zwxA:
13.62
5eexQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eexP-1zwxA:
undetectable
5eexQ-1zwxA:
undetectable		 5eexP-1zwxA:
13.62
5eexQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eexQ-1zwxA:
undetectable
5eexR-1zwxA:
undetectable		 5eexQ-1zwxA:
13.62
5eexR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eexR-1zwxA:
undetectable
5eexS-1zwxA:
undetectable		 5eexR-1zwxA:
13.62
5eexS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eexS-1zwxA:
undetectable
5eexT-1zwxA:
undetectable		 5eexS-1zwxA:
13.62
5eexT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eexT-1zwxA:
undetectable
5eexU-1zwxA:
undetectable		 5eexT-1zwxA:
13.62
5eexU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5eexU-1zwxA:
undetectable
5eexV-1zwxA:
undetectable		 5eexU-1zwxA:
13.62
5eexV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eexU-1zwxA:
undetectable
5eexV-1zwxA:
undetectable		 5eexU-1zwxA:
13.62
5eexV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eeyB-1zwxA:
undetectable
5eeyC-1zwxA:
undetectable		 5eeyB-1zwxA:
13.62
5eeyC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeyC-1zwxA:
undetectable
5eeyD-1zwxA:
undetectable		 5eeyC-1zwxA:
13.62
5eeyD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eeyD-1zwxA:
undetectable
5eeyE-1zwxA:
undetectable		 5eeyD-1zwxA:
13.62
5eeyE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeyE-1zwxA:
undetectable
5eeyF-1zwxA:
undetectable		 5eeyE-1zwxA:
13.62
5eeyF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeyG-1zwxA:
undetectable
5eeyH-1zwxA:
undetectable		 5eeyG-1zwxA:
13.62
5eeyH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eeyH-1zwxA:
undetectable
5eeyI-1zwxA:
undetectable		 5eeyH-1zwxA:
13.62
5eeyI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eeyI-1zwxA:
undetectable
5eeyJ-1zwxA:
undetectable		 5eeyI-1zwxA:
13.62
5eeyJ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eeyJ-1zwxA:
undetectable
5eeyK-1zwxA:
undetectable		 5eeyJ-1zwxA:
13.62
5eeyK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 5eeyA-1zwxA:
undetectable
5eeyK-1zwxA:
undetectable		 5eeyA-1zwxA:
13.62
5eeyK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eeyN-1zwxA:
undetectable
5eeyO-1zwxA:
undetectable		 5eeyN-1zwxA:
13.62
5eeyO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eeyO-1zwxA:
undetectable
5eeyP-1zwxA:
undetectable		 5eeyO-1zwxA:
13.62
5eeyP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5eeyP-1zwxA:
undetectable
5eeyQ-1zwxA:
undetectable		 5eeyP-1zwxA:
13.62
5eeyQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eeyP-1zwxA:
undetectable
5eeyQ-1zwxA:
undetectable		 5eeyP-1zwxA:
13.62
5eeyQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eeyQ-1zwxA:
undetectable
5eeyR-1zwxA:
undetectable		 5eeyQ-1zwxA:
13.62
5eeyR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eeyR-1zwxA:
undetectable
5eeyS-1zwxA:
undetectable		 5eeyR-1zwxA:
13.62
5eeyS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eeyS-1zwxA:
undetectable
5eeyT-1zwxA:
undetectable		 5eeyS-1zwxA:
13.62
5eeyT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eeyT-1zwxA:
undetectable
5eeyU-1zwxA:
undetectable		 5eeyT-1zwxA:
13.62
5eeyU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5eeyU-1zwxA:
undetectable
5eeyV-1zwxA:
undetectable		 5eeyU-1zwxA:
13.62
5eeyV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eeyU-1zwxA:
undetectable
5eeyV-1zwxA:
undetectable		 5eeyU-1zwxA:
13.62
5eeyV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 5eezB-1zwxA:
undetectable
5eezC-1zwxA:
undetectable		 5eezB-1zwxA:
13.62
5eezC-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eezC-1zwxA:
undetectable
5eezD-1zwxA:
undetectable		 5eezC-1zwxA:
13.62
5eezD-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eezD-1zwxA:
undetectable
5eezE-1zwxA:
undetectable		 5eezD-1zwxA:
13.62
5eezE-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eezE-1zwxA:
undetectable
5eezF-1zwxA:
undetectable		 5eezE-1zwxA:
13.62
5eezF-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eezG-1zwxA:
undetectable
5eezH-1zwxA:
undetectable		 5eezG-1zwxA:
13.62
5eezH-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eezH-1zwxA:
undetectable
5eezI-1zwxA:
undetectable		 5eezH-1zwxA:
13.62
5eezI-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5eezI-1zwxA:
undetectable
5eezJ-1zwxA:
undetectable		 5eezI-1zwxA:
13.62
5eezJ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5eezJ-1zwxA:
undetectable
5eezK-1zwxA:
undetectable		 5eezJ-1zwxA:
13.62
5eezK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.26A 5eezA-1zwxA:
undetectable
5eezK-1zwxA:
undetectable		 5eezA-1zwxA:
13.62
5eezK-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5eezN-1zwxA:
undetectable
5eezO-1zwxA:
undetectable		 5eezN-1zwxA:
13.62
5eezO-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eezO-1zwxA:
undetectable
5eezP-1zwxA:
undetectable		 5eezO-1zwxA:
13.62
5eezP-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5eezP-1zwxA:
undetectable
5eezQ-1zwxA:
undetectable		 5eezP-1zwxA:
13.62
5eezQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5eezP-1zwxA:
undetectable
5eezQ-1zwxA:
undetectable		 5eezP-1zwxA:
13.62
5eezQ-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eezQ-1zwxA:
undetectable
5eezR-1zwxA:
undetectable		 5eezQ-1zwxA:
13.62
5eezR-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5eezR-1zwxA:
undetectable
5eezS-1zwxA:
undetectable		 5eezR-1zwxA:
13.62
5eezS-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eezS-1zwxA:
undetectable
5eezT-1zwxA:
undetectable		 5eezS-1zwxA:
13.62
5eezT-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5eezT-1zwxA:
undetectable
5eezU-1zwxA:
undetectable		 5eezT-1zwxA:
13.62
5eezU-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5eezU-1zwxA:
undetectable
5eezV-1zwxA:
undetectable		 5eezU-1zwxA:
13.62
5eezV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5eezU-1zwxA:
undetectable
5eezV-1zwxA:
undetectable		 5eezU-1zwxA:
13.62
5eezV-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef0B-1zwxA:
undetectable
5ef0C-1zwxA:
undetectable		 5ef0B-1zwxA:
13.62
5ef0C-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef0C-1zwxA:
undetectable
5ef0D-1zwxA:
undetectable		 5ef0C-1zwxA:
13.62
5ef0D-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef0D-1zwxA:
undetectable
5ef0E-1zwxA:
undetectable		 5ef0D-1zwxA:
13.62
5ef0E-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef0E-1zwxA:
undetectable
5ef0F-1zwxA:
undetectable		 5ef0E-1zwxA:
13.62
5ef0F-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef0G-1zwxA:
undetectable
5ef0H-1zwxA:
undetectable		 5ef0G-1zwxA:
13.62
5ef0H-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef0H-1zwxA:
undetectable
5ef0I-1zwxA:
undetectable		 5ef0H-1zwxA:
13.62
5ef0I-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef0I-1zwxA:
undetectable
5ef0J-1zwxA:
undetectable		 5ef0I-1zwxA:
13.62
5ef0J-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef0J-1zwxA:
undetectable
5ef0K-1zwxA:
undetectable		 5ef0J-1zwxA:
13.62
5ef0K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 5ef0A-1zwxA:
undetectable
5ef0K-1zwxA:
undetectable		 5ef0A-1zwxA:
13.62
5ef0K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5ef0N-1zwxA:
undetectable
5ef0O-1zwxA:
undetectable		 5ef0N-1zwxA:
13.62
5ef0O-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef0O-1zwxA:
undetectable
5ef0P-1zwxA:
undetectable		 5ef0O-1zwxA:
13.62
5ef0P-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5ef0P-1zwxA:
undetectable
5ef0Q-1zwxA:
undetectable		 5ef0P-1zwxA:
13.62
5ef0Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5ef0P-1zwxA:
undetectable
5ef0Q-1zwxA:
undetectable		 5ef0P-1zwxA:
13.62
5ef0Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef0Q-1zwxA:
undetectable
5ef0R-1zwxA:
undetectable		 5ef0Q-1zwxA:
13.62
5ef0R-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef0R-1zwxA:
undetectable
5ef0S-1zwxA:
undetectable		 5ef0R-1zwxA:
13.62
5ef0S-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef0S-1zwxA:
undetectable
5ef0T-1zwxA:
undetectable		 5ef0S-1zwxA:
13.62
5ef0T-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef0T-1zwxA:
undetectable
5ef0U-1zwxA:
undetectable		 5ef0T-1zwxA:
13.62
5ef0U-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5ef0U-1zwxA:
undetectable
5ef0V-1zwxA:
undetectable		 5ef0U-1zwxA:
13.62
5ef0V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef0U-1zwxA:
undetectable
5ef0V-1zwxA:
undetectable		 5ef0U-1zwxA:
13.62
5ef0V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef1B-1zwxA:
undetectable
5ef1C-1zwxA:
undetectable		 5ef1B-1zwxA:
13.62
5ef1C-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef1C-1zwxA:
undetectable
5ef1D-1zwxA:
undetectable		 5ef1C-1zwxA:
13.62
5ef1D-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef1D-1zwxA:
undetectable
5ef1E-1zwxA:
undetectable		 5ef1D-1zwxA:
13.62
5ef1E-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef1E-1zwxA:
undetectable
5ef1F-1zwxA:
undetectable		 5ef1E-1zwxA:
13.62
5ef1F-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef1G-1zwxA:
undetectable
5ef1H-1zwxA:
undetectable		 5ef1G-1zwxA:
13.62
5ef1H-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef1H-1zwxA:
undetectable
5ef1I-1zwxA:
undetectable		 5ef1H-1zwxA:
13.62
5ef1I-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef1I-1zwxA:
undetectable
5ef1J-1zwxA:
undetectable		 5ef1I-1zwxA:
13.62
5ef1J-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef1J-1zwxA:
undetectable
5ef1K-1zwxA:
undetectable		 5ef1J-1zwxA:
13.62
5ef1K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.26A 5ef1A-1zwxA:
undetectable
5ef1K-1zwxA:
undetectable		 5ef1A-1zwxA:
13.62
5ef1K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5ef1N-1zwxA:
undetectable
5ef1O-1zwxA:
undetectable		 5ef1N-1zwxA:
13.62
5ef1O-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef1O-1zwxA:
undetectable
5ef1P-1zwxA:
undetectable		 5ef1O-1zwxA:
13.62
5ef1P-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5ef1P-1zwxA:
undetectable
5ef1Q-1zwxA:
undetectable		 5ef1P-1zwxA:
13.62
5ef1Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5ef1P-1zwxA:
undetectable
5ef1Q-1zwxA:
undetectable		 5ef1P-1zwxA:
13.62
5ef1Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef1Q-1zwxA:
undetectable
5ef1R-1zwxA:
undetectable		 5ef1Q-1zwxA:
13.62
5ef1R-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef1R-1zwxA:
undetectable
5ef1S-1zwxA:
undetectable		 5ef1R-1zwxA:
13.62
5ef1S-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef1S-1zwxA:
undetectable
5ef1T-1zwxA:
undetectable		 5ef1S-1zwxA:
13.62
5ef1T-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5ef1T-1zwxA:
undetectable
5ef1U-1zwxA:
undetectable		 5ef1T-1zwxA:
13.62
5ef1U-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5ef1U-1zwxA:
undetectable
5ef1V-1zwxA:
undetectable		 5ef1U-1zwxA:
13.62
5ef1V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef1U-1zwxA:
undetectable
5ef1V-1zwxA:
undetectable		 5ef1U-1zwxA:
13.62
5ef1V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef2B-1zwxA:
undetectable
5ef2C-1zwxA:
undetectable		 5ef2B-1zwxA:
13.62
5ef2C-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef2C-1zwxA:
undetectable
5ef2D-1zwxA:
undetectable		 5ef2C-1zwxA:
13.62
5ef2D-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef2D-1zwxA:
undetectable
5ef2E-1zwxA:
undetectable		 5ef2D-1zwxA:
13.62
5ef2E-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef2E-1zwxA:
undetectable
5ef2F-1zwxA:
undetectable		 5ef2E-1zwxA:
13.62
5ef2F-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef2G-1zwxA:
undetectable
5ef2H-1zwxA:
undetectable		 5ef2G-1zwxA:
13.62
5ef2H-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5ef2H-1zwxA:
undetectable
5ef2I-1zwxA:
undetectable		 5ef2H-1zwxA:
13.62
5ef2I-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef2I-1zwxA:
undetectable
5ef2J-1zwxA:
undetectable		 5ef2I-1zwxA:
13.62
5ef2J-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef2J-1zwxA:
undetectable
5ef2K-1zwxA:
undetectable		 5ef2J-1zwxA:
13.62
5ef2K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 5ef2A-1zwxA:
undetectable
5ef2K-1zwxA:
undetectable		 5ef2A-1zwxA:
13.62
5ef2K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5ef2N-1zwxA:
undetectable
5ef2O-1zwxA:
undetectable		 5ef2N-1zwxA:
13.62
5ef2O-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef2O-1zwxA:
undetectable
5ef2P-1zwxA:
undetectable		 5ef2O-1zwxA:
13.62
5ef2P-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5ef2P-1zwxA:
undetectable
5ef2Q-1zwxA:
undetectable		 5ef2P-1zwxA:
13.62
5ef2Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5ef2P-1zwxA:
undetectable
5ef2Q-1zwxA:
undetectable		 5ef2P-1zwxA:
13.62
5ef2Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 5ef2Q-1zwxA:
undetectable
5ef2R-1zwxA:
undetectable		 5ef2Q-1zwxA:
13.62
5ef2R-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef2R-1zwxA:
undetectable
5ef2S-1zwxA:
undetectable		 5ef2R-1zwxA:
13.62
5ef2S-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef2S-1zwxA:
undetectable
5ef2T-1zwxA:
undetectable		 5ef2S-1zwxA:
13.62
5ef2T-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef2T-1zwxA:
undetectable
5ef2U-1zwxA:
undetectable		 5ef2T-1zwxA:
13.62
5ef2U-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5ef2U-1zwxA:
undetectable
5ef2V-1zwxA:
undetectable		 5ef2U-1zwxA:
13.62
5ef2V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef2U-1zwxA:
undetectable
5ef2V-1zwxA:
undetectable		 5ef2U-1zwxA:
13.62
5ef2V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.20A 5ef3B-1zwxA:
undetectable
5ef3C-1zwxA:
undetectable		 5ef3B-1zwxA:
13.62
5ef3C-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef3C-1zwxA:
undetectable
5ef3D-1zwxA:
undetectable		 5ef3C-1zwxA:
13.62
5ef3D-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef3D-1zwxA:
undetectable
5ef3E-1zwxA:
undetectable		 5ef3D-1zwxA:
13.62
5ef3E-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef3E-1zwxA:
undetectable
5ef3F-1zwxA:
undetectable		 5ef3E-1zwxA:
13.62
5ef3F-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef3G-1zwxA:
undetectable
5ef3H-1zwxA:
undetectable		 5ef3G-1zwxA:
13.62
5ef3H-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef3H-1zwxA:
undetectable
5ef3I-1zwxA:
undetectable		 5ef3H-1zwxA:
13.62
5ef3I-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.24A 5ef3I-1zwxA:
undetectable
5ef3J-1zwxA:
undetectable		 5ef3I-1zwxA:
13.62
5ef3J-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.21A 5ef3J-1zwxA:
undetectable
5ef3K-1zwxA:
undetectable		 5ef3J-1zwxA:
13.62
5ef3K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.25A 5ef3A-1zwxA:
undetectable
5ef3K-1zwxA:
undetectable		 5ef3A-1zwxA:
13.62
5ef3K-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5ef3N-1zwxA:
undetectable
5ef3O-1zwxA:
undetectable		 5ef3N-1zwxA:
13.62
5ef3O-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.18A 5ef3O-1zwxA:
undetectable
5ef3P-1zwxA:
undetectable		 5ef3O-1zwxA:
13.62
5ef3P-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.33A 5ef3P-1zwxA:
undetectable
5ef3Q-1zwxA:
undetectable		 5ef3P-1zwxA:
13.62
5ef3Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.22A 5ef3P-1zwxA:
undetectable
5ef3Q-1zwxA:
undetectable		 5ef3P-1zwxA:
13.62
5ef3Q-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 9 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef3Q-1zwxA:
undetectable
5ef3R-1zwxA:
undetectable		 5ef3Q-1zwxA:
13.62
5ef3R-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.17A 5ef3R-1zwxA:
undetectable
5ef3S-1zwxA:
undetectable		 5ef3R-1zwxA:
13.62
5ef3S-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef3S-1zwxA:
undetectable
5ef3T-1zwxA:
undetectable		 5ef3S-1zwxA:
13.62
5ef3T-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.23A 5ef3T-1zwxA:
undetectable
5ef3U-1zwxA:
undetectable		 5ef3T-1zwxA:
13.62
5ef3U-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 183
THR A 186
HIS A 185
THR A 184
ILE A 182
 None
 1.32A 5ef3U-1zwxA:
undetectable
5ef3V-1zwxA:
undetectable		 5ef3U-1zwxA:
13.62
5ef3V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 10 GLY A 227
THR A 186
HIS A 185
THR A 184
ILE A 226
 None
 1.19A 5ef3U-1zwxA:
undetectable
5ef3V-1zwxA:
undetectable		 5ef3U-1zwxA:
13.62
5ef3V-1zwxA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 8 ILE A  72
ALA A  73
VAL A 140
VAL A  84
 None
 0.51A 5l94A-1zwxA:
undetectable		 5l94A-1zwxA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		4 / 6 ASP A 229
HIS A 185
LEU A 281
HIS A 325
 None
None
None
PO4  A 401 (-3.8A)
 1.03A 5nelB-1zwxA:
undetectable
5nelC-1zwxA:
undetectable		 5nelB-1zwxA:
23.44
5nelC-1zwxA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 12 ILE A 226
LEU A 246
SER A  49
GLY A 183
GLY A 228
 None
 1.16A 5nnaA-1zwxA:
undetectable		 5nnaA-1zwxA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 12 ILE A 226
LEU A 246
SER A  49
GLY A 183
GLY A 228
 None
 1.15A 5nnaB-1zwxA:
undetectable		 5nnaB-1zwxA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 12 ILE A 226
LEU A 246
SER A  49
GLY A 183
GLY A 228
 None
 1.15A 5nnaC-1zwxA:
undetectable		 5nnaC-1zwxA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 12 ILE A 226
LEU A 246
SER A  49
GLY A 183
GLY A 228
 None
 1.18A 5nnaD-1zwxA:
undetectable		 5nnaD-1zwxA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 VAL A 137
GLY A 135
SER A 163
ALA A 131
ASN A 231
 None
None
None
None
PO4  A 401 ( 4.3A)
 1.43A 6hu9A-1zwxA:
undetectable
6hu9E-1zwxA:
undetectable
6hu9I-1zwxA:
undetectable		 6hu9A-1zwxA:
20.93
6hu9E-1zwxA:
19.93
6hu9I-1zwxA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zwx SPHINGOMYELINASE-C
(Listeria
ivanovii) 		5 / 11 GLY A 136
GLN A 150
THR A 110
PHE A 167
GLY A 183
 None
 1.25A 6nknA-1zwxA:
undetectable
6nknB-1zwxA:
0.0
6nknT-1zwxA:
0.0		 6nknA-1zwxA:
19.15
6nknB-1zwxA:
20.85
6nknT-1zwxA:
12.54