SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zx5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 5 TYR A 257
LEU A 251
THR A 265
ARG A 261
 None
 1.27A 1i2wA-1zx5A:
undetectable		 1i2wA-1zx5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 6 TRP A 200
ASN A 196
LEU A 145
PHE A 152
 None
ACY  A 505 (-3.5A)
None
None
 1.32A 1ru9H-1zx5A:
undetectable
1ru9L-1zx5A:
undetectable		 1ru9H-1zx5A:
20.50
1ru9L-1zx5A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 6 TRP A 200
ASN A 196
LEU A 145
PHE A 152
 None
ACY  A 505 (-3.5A)
None
None
 1.36A 1rukH-1zx5A:
undetectable
1rukL-1zx5A:
undetectable		 1rukH-1zx5A:
20.50
1rukL-1zx5A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		3 / 3 TRP A  39
LEU A  14
LYS A  28
 None
None
ACY  A 503 (-2.7A)
 1.29A 1yajK-1zx5A:
undetectable		 1yajK-1zx5A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		3 / 3 PHE A 195
VAL A 203
TRP A 200
 None
 0.65A 2cc8A-1zx5A:
1.4		 2cc8A-1zx5A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		3 / 3 PHE A 195
VAL A 203
TRP A 200
 None
 0.65A 2ccbA-1zx5A:
1.4		 2ccbA-1zx5A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		3 / 3 PHE A 195
VAL A 203
TRP A 200
 None
 0.65A 2vx9A-1zx5A:
1.3		 2vx9A-1zx5A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 4 GLY A  21
GLY A  20
GLY A  36
GLY A  34
 None
 0.66A 3bogD-1zx5A:
undetectable		 3bogD-1zx5A:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A  41
ILE A   7
PHE A 283
VAL A 234
ILE A 292
 None
 1.34A 3em0B-1zx5A:
undetectable		 3em0B-1zx5A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 9 LEU A 109
SER A 189
VAL A  99
GLY A 172
PRO A 171
 None
None
None
None
EDO  A 801 (-4.5A)
 1.29A 3hcoA-1zx5A:
undetectable		 3hcoA-1zx5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 109
SER A 189
VAL A  99
GLY A 172
PRO A 171
 None
None
None
None
EDO  A 801 (-4.5A)
 1.36A 3hcoB-1zx5A:
undetectable		 3hcoB-1zx5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 180
THR A  95
HIS A  98
ILE A 169
HIS A 175
 None
ACY  A 506 ( 3.0A)
GOL  A 700 ( 4.2A)
None
GOL  A 700 (-4.1A)
 1.43A 3kcxA-1zx5A:
3.9		 3kcxA-1zx5A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 GLU A 288
TYR A 257
GLY A 290
ILE A 292
ALA A 253
 None
 1.15A 3nmuB-1zx5A:
undetectable
3nmuJ-1zx5A:
undetectable		 3nmuB-1zx5A:
22.34
3nmuJ-1zx5A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 5 PHE A   8
GLY A 262
THR A 280
VAL A 276
 None
 1.02A 3wrkD-1zx5A:
undetectable		 3wrkD-1zx5A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 8 ASN A 196
VAL A 203
PHE A 152
LEU A 145
 ACY  A 505 (-3.5A)
None
None
None
 1.11A 4f8hB-1zx5A:
undetectable
4f8hC-1zx5A:
undetectable		 4f8hB-1zx5A:
21.99
4f8hC-1zx5A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 5 VAL A 285
LEU A 251
VAL A 276
PHE A 283
 None
 1.00A 4lb0B-1zx5A:
undetectable		 4lb0B-1zx5A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.41A 4qvlV-1zx5A:
undetectable
4qvlb-1zx5A:
undetectable		 4qvlV-1zx5A:
23.08
4qvlb-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.40A 4qvlH-1zx5A:
undetectable
4qvlN-1zx5A:
undetectable		 4qvlH-1zx5A:
23.08
4qvlN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 4qvmV-1zx5A:
undetectable
4qvmb-1zx5A:
undetectable		 4qvmV-1zx5A:
23.08
4qvmb-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 4qvmH-1zx5A:
undetectable
4qvmN-1zx5A:
undetectable		 4qvmH-1zx5A:
23.08
4qvmN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.45A 4qvpV-1zx5A:
undetectable
4qvpb-1zx5A:
undetectable		 4qvpV-1zx5A:
23.08
4qvpb-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.45A 4qvpH-1zx5A:
undetectable
4qvpN-1zx5A:
undetectable		 4qvpH-1zx5A:
23.08
4qvpN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.44A 4qvqV-1zx5A:
undetectable
4qvqb-1zx5A:
undetectable		 4qvqV-1zx5A:
23.08
4qvqb-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.45A 4qvqH-1zx5A:
undetectable
4qvqN-1zx5A:
undetectable		 4qvqH-1zx5A:
23.08
4qvqN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.43A 4qvwV-1zx5A:
undetectable
4qvwb-1zx5A:
undetectable		 4qvwV-1zx5A:
23.08
4qvwb-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 4qvwH-1zx5A:
undetectable
4qvwN-1zx5A:
undetectable		 4qvwH-1zx5A:
23.08
4qvwN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.43A 4qw0V-1zx5A:
undetectable
4qw0b-1zx5A:
undetectable		 4qw0V-1zx5A:
23.08
4qw0b-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.43A 4qw0H-1zx5A:
undetectable
4qw0N-1zx5A:
undetectable		 4qw0H-1zx5A:
23.08
4qw0N-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.41A 4qw1V-1zx5A:
undetectable
4qw1b-1zx5A:
undetectable		 4qw1V-1zx5A:
23.08
4qw1b-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.40A 4qw1H-1zx5A:
undetectable
4qw1N-1zx5A:
undetectable		 4qw1H-1zx5A:
23.08
4qw1N-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.43A 4qw3V-1zx5A:
undetectable
4qw3b-1zx5A:
undetectable		 4qw3V-1zx5A:
23.08
4qw3b-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 4qw3H-1zx5A:
undetectable
4qw3N-1zx5A:
undetectable		 4qw3H-1zx5A:
23.08
4qw3N-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.43A 4qwuV-1zx5A:
undetectable
4qwub-1zx5A:
undetectable		 4qwuV-1zx5A:
23.08
4qwub-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 4qwuH-1zx5A:
undetectable
4qwuN-1zx5A:
undetectable		 4qwuH-1zx5A:
23.08
4qwuN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_A_ACTA403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		3 / 3 VAL A 203
LEU A 207
VAL A  99
 None
 0.60A 4wq4A-1zx5A:
undetectable		 4wq4A-1zx5A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 8 SER A 186
ALA A 192
LEU A 191
GLY A 115
 None
None
None
EDO  A 801 ( 4.2A)
 0.79A 4xk8a-1zx5A:
undetectable		 4xk8a-1zx5A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 SER A  59
PHE A  82
PHE A  41
GLU A 264
GLY A  55
 None
 1.39A 4zjlA-1zx5A:
0.0		 4zjlA-1zx5A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 8 ALA A  75
VAL A 299
GLY A  73
ALA A 278
GLY A 246
 None
 1.19A 4zjzB-1zx5A:
undetectable		 4zjzB-1zx5A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 5bxnH-1zx5A:
undetectable
5bxnN-1zx5A:
undetectable		 5bxnH-1zx5A:
23.23
5bxnN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.41A 5cz7H-1zx5A:
undetectable
5cz7N-1zx5A:
undetectable		 5cz7H-1zx5A:
23.08
5cz7N-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 5d0xV-1zx5A:
undetectable
5d0xb-1zx5A:
undetectable		 5d0xV-1zx5A:
23.08
5d0xb-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.42A 5d0xH-1zx5A:
undetectable
5d0xN-1zx5A:
undetectable		 5d0xH-1zx5A:
23.08
5d0xN-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.46A 5l66V-1zx5A:
undetectable
5l66b-1zx5A:
undetectable		 5l66V-1zx5A:
23.08
5l66b-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 11 HIS A 175
THR A  95
GLY A 126
ALA A 128
THR A 161
 GOL  A 700 (-4.1A)
ACY  A 506 ( 3.0A)
None
None
None
 1.46A 5l66H-1zx5A:
undetectable
5l66N-1zx5A:
undetectable		 5l66H-1zx5A:
23.08
5l66N-1zx5A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		4 / 5 ILE A  89
HIS A 175
HIS A 100
HIS A  98
 ACY  A 506 ( 4.7A)
GOL  A 700 (-4.1A)
GOL  A 700 (-4.5A)
GOL  A 700 ( 4.2A)
 1.03A 5n5kA-1zx5A:
undetectable		 5n5kA-1zx5A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE
(Archaeoglobus
fulgidus) 		5 / 12 GLU A 255
GLY A 290
TYR A 164
VAL A 285
GLY A 238
 None
None
ACY  A 502 (-4.5A)
None
None
 1.13A 6gngA-1zx5A:
undetectable		 6gngA-1zx5A:
20.68