SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zxq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		5 / 12 GLY A 103
ALA A 155
ASP A 156
ASP A 159
VAL A 100
 None
 0.96A 1k6cB-1zxqA:
undetectable		 1k6cB-1zxqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		4 / 6 LEU A  40
LEU A  55
LEU A  20
LEU A  36
 None
 0.90A 2ab2A-1zxqA:
undetectable		 2ab2A-1zxqA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		3 / 3 SER A 153
GLU A 130
ASP A 156
 None
 0.82A 3bwmA-1zxqA:
undetectable		 3bwmA-1zxqA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		3 / 3 SER A 153
GLU A 130
ASP A 156
 None
 0.76A 3bwyA-1zxqA:
undetectable		 3bwyA-1zxqA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		5 / 12 GLY A 103
ALA A 155
ASP A 156
ASP A 159
VAL A 100
 None
 0.92A 3el4A-1zxqA:
undetectable		 3el4A-1zxqA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		5 / 12 GLY A 103
ALA A 155
ASP A 156
ASP A 159
VAL A 100
 None
 0.87A 3el5B-1zxqA:
undetectable		 3el5B-1zxqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		5 / 9 GLY A 103
ALA A 155
ASP A 156
ASP A 159
VAL A 100
 None
 0.90A 3u7sA-1zxqA:
undetectable		 3u7sA-1zxqA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		5 / 9 GLY A 103
ALA A 155
ASP A 156
ASP A 159
VAL A 100
 None
 0.91A 3u7sB-1zxqA:
undetectable		 3u7sB-1zxqA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		5 / 11 GLY A 103
ALA A 155
ASP A 156
ASP A 159
VAL A 100
 None
 0.93A 4l1aA-1zxqA:
undetectable		 4l1aA-1zxqA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		4 / 6 GLU A   4
PHE A   3
PHE A  69
HIS A   6
 None
 1.39A 4uciA-1zxqA:
undetectable		 4uciA-1zxqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		4 / 7 GLU A   4
PHE A   3
PHE A  69
HIS A   6
 None
 1.41A 4uciB-1zxqA:
undetectable		 4uciB-1zxqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		3 / 3 SER A 153
GLU A 130
ASP A 156
 None
 0.84A 4xudA-1zxqA:
undetectable		 4xudA-1zxqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1zxq INTERCELLULAR
ADHESION MOLECULE-2
(Homo
sapiens) 		4 / 4 LEU A 125
LEU A 123
SER A 184
ALA A 168
 None
 1.13A 5uunA-1zxqA:
undetectable		 5uunA-1zxqA:
24.37