SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 7 TYR A 117
VAL A 204
VAL A 159
VAL A 148
 None
 0.91A 2qbnA-1zxuA:
undetectable		 2qbnA-1zxuA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		3 / 3 VAL A 119
VAL A 104
TRP A 102
 None
 0.77A 3l8lA-1zxuA:
undetectable
3l8lB-1zxuA:
undetectable		 3l8lA-1zxuA:
8.00
3l8lB-1zxuA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 5 ASP A 145
VAL A 168
PHE A 199
GLY A  25
 None
 1.23A 4xp6A-1zxuA:
undetectable		 4xp6A-1zxuA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 4 VAL A 133
VAL A 119
TYR A 117
GLN A 103
 None
 1.38A 5qggA-1zxuA:
undetectable		 5qggA-1zxuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 4 VAL A 133
VAL A 119
TYR A 117
GLN A 103
 None
 1.37A 5qgoA-1zxuA:
undetectable		 5qgoA-1zxuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 4 VAL A 133
VAL A 119
TYR A 117
GLN A 103
 None
 1.37A 5qgpA-1zxuA:
undetectable		 5qgpA-1zxuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 4 VAL A 133
VAL A 119
TYR A 117
GLN A 103
 None
 1.34A 5qgqA-1zxuA:
undetectable		 5qgqA-1zxuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 4 VAL A 133
VAL A 119
TYR A 117
GLN A 103
 None
 1.35A 5qhbA-1zxuA:
undetectable		 5qhbA-1zxuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1zxu AT5G01750 PROTEIN
(Arabidopsis
thaliana) 		4 / 8 ASP A  51
ARG A  78
ASP A 209
GLU A  93
 None
 1.20A 6mn4D-1zxuA:
undetectable		 6mn4D-1zxuA:
23.16