SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zyl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 8 ASP A 220
ASP A 219
TRP A  62
ARG A 283
 None
 1.16A 1ceaA-1zylA:
undetectable
1ceaB-1zylA:
undetectable		 1ceaA-1zylA:
11.65
1ceaB-1zylA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 7 ASP A 220
ASP A 219
TRP A  62
ARG A 283
 None
 1.27A 1ceaB-1zylA:
undetectable		 1ceaB-1zylA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 7 ASP A 220
ASP A 219
TRP A  62
ARG A 283
 None
 1.12A 1cebB-1zylA:
undetectable		 1cebB-1zylA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 7 VAL A  53
LEU A  34
THR A  32
LEU A  31
 None
 0.78A 1jgsA-1zylA:
undetectable		 1jgsA-1zylA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 5 LEU A 159
ALA A 163
TRP A 303
LEU A 165
 None
 1.25A 2oaxA-1zylA:
undetectable		 2oaxA-1zylA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 4 PRO A 145
THR A 146
GLY A 136
THR A 135
 None
 1.18A 3ib1A-1zylA:
undetectable		 3ib1A-1zylA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 8 VAL A  41
VAL A  53
PHE A 106
ASP A 217
 None
 0.63A 3warA-1zylA:
8.4		 3warA-1zylA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		3 / 3 TYR A 276
PHE A   6
ARG A 283
 None
 1.08A 4g19D-1zylA:
undetectable		 4g19D-1zylA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 8 ARG A 222
TYR A 152
ARG A 273
ASP A 217
 None
 1.33A 4kr4C-1zylA:
undetectable		 4kr4C-1zylA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		5 / 12 GLN A 244
LEU A 245
GLY A 126
ASP A 120
ALA A 251
 None
 1.16A 4pclA-1zylA:
undetectable		 4pclA-1zylA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 7 ASN A  39
ASP A 217
ASP A 201
GLY A 200
 None
 1.06A 5x7pA-1zylA:
undetectable		 5x7pA-1zylA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 8 VAL A  41
VAL A  53
PHE A 106
ASP A 217
 None
 0.67A 5y9mA-1zylA:
6.9		 5y9mA-1zylA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 8 VAL A  41
VAL A  53
PHE A 106
ASP A 217
 None
 0.68A 5y9mX-1zylA:
7.9		 5y9mX-1zylA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 7 VAL A  41
VAL A  53
PHE A 106
ASP A 217
 None
 0.83A 5yf9B-1zylA:
7.3		 5yf9B-1zylA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 1zyl HYPOTHETICAL PROTEIN
YIHE
(Escherichia
coli) 		4 / 7 VAL A  41
VAL A  53
PHE A 106
ASP A 217
 None
 0.60A 5ywmX-1zylA:
7.7		 5ywmX-1zylA:
12.80