SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zzm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 HIS A  11
MET A  69
HIS A 157
ASP A 207
ASP A 210
 ZN  A 401 (-3.2A)
P33  A 501 (-3.7A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
P33  A 501 (-3.7A)
 1.39A 1a4lB-1zzmA:
14.1		 1a4lB-1zzmA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 HIS A   9
HIS A  66
HIS A 133
ASP A 207
 ZN  A 401 (-3.3A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.2A)
 0.79A 1e9yB-1zzmA:
14.5		 1e9yB-1zzmA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 6 HIS A   9
HIS A  11
HIS A  66
HIS A 133
ASP A 207
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.2A)
 0.82A 1fweC-1zzmA:
14.1		 1fweC-1zzmA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 GLU A  97
HIS A  66
HIS A 133
HIS A 157
ASP A 207
 ZN  A 401 ( 2.3A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
 0.99A 1ituA-1zzmA:
14.6		 1ituA-1zzmA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 GLU A  97
HIS A  66
HIS A 133
HIS A 157
ASP A 207
 ZN  A 401 ( 2.3A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
 1.00A 1ituB-1zzmA:
2.0		 1ituB-1zzmA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 8 GLU A  97
HIS A 157
ASP A 207
HIS A  11
GLU A 205
 ZN  A 401 ( 2.3A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
None
 1.30A 1v7zA-1zzmA:
2.3		 1v7zA-1zzmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 8 GLU A  97
HIS A 157
ASP A 207
HIS A  11
GLU A 205
 ZN  A 401 ( 2.3A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
None
 1.30A 1v7zB-1zzmA:
2.4		 1v7zB-1zzmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 8 GLU A  97
HIS A 157
ASP A 207
HIS A  11
GLU A 205
 ZN  A 401 ( 2.3A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
None
 1.30A 1v7zD-1zzmA:
undetectable		 1v7zD-1zzmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 8 GLU A  97
HIS A 157
ASP A 207
HIS A  11
GLU A 205
 ZN  A 401 ( 2.3A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
None
 1.30A 1v7zE-1zzmA:
2.3		 1v7zE-1zzmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 8 GLU A  97
HIS A 157
ASP A 207
HIS A  11
GLU A 205
 ZN  A 401 ( 2.3A)
ZN  A 402 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
None
 1.30A 1v7zF-1zzmA:
undetectable		 1v7zF-1zzmA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		3 / 3 PRO A 129
THR A 153
PRO A 151
 None
 0.68A 2d55C-1zzmA:
undetectable		 2d55C-1zzmA:
4.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 ASN A 257
ALA A  53
VAL A  93
ALA A  94
ILE A 131
 None
 1.11A 2h42B-1zzmA:
undetectable		 2h42B-1zzmA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 8 ALA A 247
LEU A 248
LEU A 204
VAL A 229
ILE A 182
 None
 1.18A 2uxpA-1zzmA:
undetectable		 2uxpA-1zzmA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 7 GLU A  97
ALA A  94
PRO A  39
ALA A  62
 ZN  A 401 ( 2.3A)
None
None
None
 1.08A 2zgwA-1zzmA:
undetectable		 2zgwA-1zzmA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 6 GLU A  97
ALA A  94
PRO A  39
ALA A  62
 ZN  A 401 ( 2.3A)
None
None
None
 1.13A 2zgwB-1zzmA:
undetectable		 2zgwB-1zzmA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.15A 3ko0A-1zzmA:
undetectable
3ko0B-1zzmA:
0.0
3ko0C-1zzmA:
undetectable
3ko0D-1zzmA:
undetectable		 3ko0A-1zzmA:
14.89
3ko0B-1zzmA:
14.89
3ko0C-1zzmA:
14.89
3ko0D-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 6 LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 0.95A 3ko0B-1zzmA:
undetectable		 3ko0B-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.16A 3ko0A-1zzmA:
undetectable
3ko0B-1zzmA:
0.0
3ko0C-1zzmA:
undetectable
3ko0D-1zzmA:
undetectable		 3ko0A-1zzmA:
14.89
3ko0B-1zzmA:
14.89
3ko0C-1zzmA:
14.89
3ko0D-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.18A 3ko0C-1zzmA:
undetectable
3ko0D-1zzmA:
undetectable
3ko0E-1zzmA:
0.0
3ko0F-1zzmA:
undetectable		 3ko0C-1zzmA:
14.89
3ko0D-1zzmA:
14.89
3ko0E-1zzmA:
14.89
3ko0F-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.21A 3ko0C-1zzmA:
undetectable
3ko0D-1zzmA:
undetectable
3ko0E-1zzmA:
0.0
3ko0F-1zzmA:
undetectable		 3ko0C-1zzmA:
14.89
3ko0D-1zzmA:
14.89
3ko0E-1zzmA:
14.89
3ko0F-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.15A 3ko0E-1zzmA:
0.0
3ko0F-1zzmA:
undetectable
3ko0G-1zzmA:
0.0
3ko0H-1zzmA:
undetectable		 3ko0E-1zzmA:
14.89
3ko0F-1zzmA:
14.89
3ko0G-1zzmA:
14.89
3ko0H-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.18A 3ko0G-1zzmA:
0.0
3ko0H-1zzmA:
undetectable
3ko0I-1zzmA:
0.0
3ko0J-1zzmA:
0.0		 3ko0G-1zzmA:
14.89
3ko0H-1zzmA:
14.89
3ko0I-1zzmA:
14.89
3ko0J-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.17A 3ko0A-1zzmA:
undetectable
3ko0B-1zzmA:
0.0
3ko0I-1zzmA:
0.0
3ko0J-1zzmA:
0.0		 3ko0A-1zzmA:
14.89
3ko0B-1zzmA:
14.89
3ko0I-1zzmA:
14.89
3ko0J-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.16A 3ko0K-1zzmA:
0.0
3ko0L-1zzmA:
undetectable
3ko0S-1zzmA:
0.0
3ko0T-1zzmA:
undetectable		 3ko0K-1zzmA:
14.89
3ko0L-1zzmA:
14.89
3ko0S-1zzmA:
14.89
3ko0T-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.14A 3ko0K-1zzmA:
0.0
3ko0L-1zzmA:
undetectable
3ko0M-1zzmA:
0.0
3ko0N-1zzmA:
undetectable		 3ko0K-1zzmA:
14.89
3ko0L-1zzmA:
14.89
3ko0M-1zzmA:
14.89
3ko0N-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.18A 3ko0M-1zzmA:
0.0
3ko0N-1zzmA:
undetectable
3ko0O-1zzmA:
undetectable
3ko0P-1zzmA:
undetectable		 3ko0M-1zzmA:
14.89
3ko0N-1zzmA:
14.89
3ko0O-1zzmA:
14.89
3ko0P-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.18A 3ko0K-1zzmA:
0.0
3ko0L-1zzmA:
undetectable
3ko0M-1zzmA:
0.0
3ko0N-1zzmA:
undetectable		 3ko0K-1zzmA:
14.89
3ko0L-1zzmA:
14.89
3ko0M-1zzmA:
14.89
3ko0N-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 11 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.17A 3ko0O-1zzmA:
undetectable
3ko0P-1zzmA:
undetectable
3ko0Q-1zzmA:
0.0
3ko0R-1zzmA:
undetectable		 3ko0O-1zzmA:
14.89
3ko0P-1zzmA:
14.89
3ko0Q-1zzmA:
14.89
3ko0R-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 ASP A  13
LEU A  25
SER A  24
ILE A  36
CYH A  10
 None
 1.17A 3ko0M-1zzmA:
0.0
3ko0N-1zzmA:
undetectable
3ko0O-1zzmA:
undetectable
3ko0P-1zzmA:
undetectable		 3ko0M-1zzmA:
14.89
3ko0N-1zzmA:
14.89
3ko0O-1zzmA:
14.89
3ko0P-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 10 LEU A  25
SER A  24
ILE A  36
CYH A  10
ASP A  13
 None
 1.17A 3ko0O-1zzmA:
undetectable
3ko0P-1zzmA:
undetectable
3ko0Q-1zzmA:
0.0
3ko0R-1zzmA:
0.0		 3ko0O-1zzmA:
14.89
3ko0P-1zzmA:
14.89
3ko0Q-1zzmA:
14.89
3ko0R-1zzmA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 8 ALA A 226
VAL A 229
LEU A 233
LEU A 203
 None
 0.78A 3roxA-1zzmA:
2.5		 3roxA-1zzmA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 9 LEU A 115
LEU A 116
GLY A  99
VAL A  95
VAL A 130
 None
 1.47A 4c9kB-1zzmA:
undetectable		 4c9kB-1zzmA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 8 PHE A  46
GLY A  64
LEU A  65
ILE A  98
 None
 0.84A 4em2A-1zzmA:
undetectable		 4em2A-1zzmA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 HIS A   9
HIS A  66
HIS A 133
ASP A 207
 ZN  A 401 (-3.3A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.2A)
 0.71A 4h9mA-1zzmA:
13.3		 4h9mA-1zzmA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		3 / 3 LEU A  59
PRO A  58
ARG A 222
 None
 0.73A 4klrB-1zzmA:
undetectable		 4klrB-1zzmA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 6 HIS A   9
HIS A  11
HIS A  66
HIS A 133
ASP A 207
 ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
ZN  A 401 (-3.2A)
 0.70A 4ubpC-1zzmA:
14.2		 4ubpC-1zzmA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		3 / 3 HIS A  11
HIS A  66
HIS A 133
 ZN  A 401 (-3.2A)
P33  A 501 (-4.0A)
ZN  A 402 (-3.1A)
 0.95A 5oexA-1zzmA:
undetectable		 5oexA-1zzmA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 LEU A 122
LYS A 121
ALA A 123
LEU A 128
 None
 0.87A 5vkqA-1zzmA:
undetectable
5vkqD-1zzmA:
undetectable		 5vkqA-1zzmA:
10.03
5vkqD-1zzmA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 LEU A 122
LYS A 121
ALA A 123
LEU A 128
 None
 0.87A 5vkqA-1zzmA:
undetectable
5vkqB-1zzmA:
undetectable		 5vkqA-1zzmA:
10.03
5vkqB-1zzmA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 LEU A 122
LYS A 121
ALA A 123
LEU A 128
 None
 0.86A 5vkqB-1zzmA:
undetectable
5vkqC-1zzmA:
undetectable		 5vkqB-1zzmA:
10.03
5vkqC-1zzmA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 LEU A 122
LYS A 121
ALA A 123
LEU A 128
 None
 0.86A 5vkqC-1zzmA:
undetectable
5vkqD-1zzmA:
undetectable		 5vkqC-1zzmA:
10.03
5vkqD-1zzmA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 THR A 190
ILE A 194
LEU A 100
PHE A 169
LEU A 145
 None
 1.42A 6a93A-1zzmA:
undetectable		 6a93A-1zzmA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		4 / 5 THR A  41
HIS A   9
ASP A 207
HIS A 157
 P33  A 501 ( 4.6A)
ZN  A 401 (-3.3A)
ZN  A 401 (-3.2A)
ZN  A 402 (-3.3A)
 0.88A 6dchA-1zzmA:
undetectable		 6dchA-1zzmA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		5 / 12 VAL A 130
LEU A 150
GLY A 154
LEU A 145
LEU A 120
 None
 1.00A 6f6iA-1zzmA:
undetectable
6f6iB-1zzmA:
undetectable		 6f6iA-1zzmA:
17.20
6f6iB-1zzmA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB503_0
(AMINE OXIDASE LKCE)		 1zzm PUTATIVE
DEOXYRIBONUCLEASE
YJJV
(Escherichia
coli) 		3 / 3 VAL A 178
GLU A 205
ILE A 182
 None
 0.65A 6f7lB-1zzmA:
undetectable		 6f7lB-1zzmA:
20.13