SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a0a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2a0a DER F 13
(Dermatophagoides
farinae) 		4 / 4 ASP A  99
GLY A  98
LYS A 100
GLU A 101
 None
 1.46A 3hznD-2a0aA:
undetectable		 3hznD-2a0aA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 2a0a DER F 13
(Dermatophagoides
farinae) 		4 / 6 ILE A  84
PHE A  51
ARG A 106
ILE A 104
 None
 1.24A 4zzcA-2a0aA:
undetectable
4zzcB-2a0aA:
undetectable		 4zzcA-2a0aA:
19.05
4zzcB-2a0aA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 2a0a DER F 13
(Dermatophagoides
farinae) 		4 / 6 ILE A  84
PHE A  51
ARG A 106
ILE A 104
 None
 1.21A 4zzcB-2a0aA:
undetectable
4zzcC-2a0aA:
undetectable		 4zzcB-2a0aA:
19.05
4zzcC-2a0aA:
19.05