SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		5 / 12 TYR D  27
ILE D  29
ASN D  36
LEU D   4
ASP D 101
 None
 1.45A 1mrlB-2a0lD:
undetectable
1mrlC-2a0lD:
undetectable		 1mrlB-2a0lD:
17.86
1mrlC-2a0lD:
17.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		4 / 8 ALA D  34
ASN D  36
TRP D  48
TYR D  51
 None
 0.35A 1rukH-2a0lD:
20.2
1rukL-2a0lD:
13.9		 1rukH-2a0lD:
52.63
1rukL-2a0lD:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2a0l 33H1 FV FRAGMENT
33H1 FV FRAGMENT
(Mus
musculus;
Mus
musculus) 		4 / 8 GLY D  99
ASN D  36
PHE C  92
TYR D  51
 None
 0.85A 3ccfA-2a0lD:
undetectable		 3ccfA-2a0lD:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		3 / 3 ASP C  83
LEU C 104
GLN C   6
 None
 0.82A 3g4lA-2a0lC:
undetectable		 3g4lA-2a0lC:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		4 / 7 GLY D  43
ASN D  44
TYR C  88
THR C  97
 None
 0.74A 3tajA-2a0lD:
undetectable		 3tajA-2a0lD:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		4 / 7 THR C  20
ARG C  18
PHE C  63
SER C  64
 None
 1.25A 4o4dA-2a0lC:
undetectable		 4o4dA-2a0lC:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		3 / 3 LEU D  46
MET D 105
TYR C  87
 None
 0.84A 4p6xG-2a0lD:
undetectable		 4p6xG-2a0lD:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		5 / 12 GLY D  99
TYR D  51
PHE D  95
TYR D 107
LEU D   4
 None
 1.08A 5czyA-2a0lD:
undetectable		 5czyA-2a0lD:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 2a0l 33H1 FV FRAGMENT
(Mus
musculus) 		3 / 3 ARG D  67
ILE D  68
SER D  66
 None
 0.83A 5zw2A-2a0lD:
undetectable		 5zw2A-2a0lD:
13.88