SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		5 / 12 ALA A  65
ALA A  24
ILE A  79
ILE A  10
ILE A  48
 None
 0.86A 1fk6A-2a18A:
undetectable		 1fk6A-2a18A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		5 / 11 ALA A  72
THR A  12
ILE A  18
ALA A  65
ALA A  21
 NH4  A 126 (-4.3A)
None
None
None
None
 1.17A 2qhfA-2a18A:
undetectable		 2qhfA-2a18A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		5 / 10 GLY A  40
ALA A  39
ILE A  18
GLY A  14
THR A  76
 None
 1.08A 3el9B-2a18A:
undetectable		 3el9B-2a18A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A  63
GLY A  62
ILE A  31
ALA A  65
VAL A  74
 None
 1.01A 3fpjA-2a18A:
undetectable		 3fpjA-2a18A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_B_TMQB612_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		5 / 9 VAL A  26
ALA A  24
ILE A  66
PHE A  44
ILE A  48
 None
 1.45A 3hbbB-2a18A:
undetectable		 3hbbB-2a18A:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		4 / 8 VAL A  55
GLY A   8
ILE A  93
GLY A  50
 None
 0.81A 3n9jB-2a18A:
undetectable		 3n9jB-2a18A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLY A  40
ALA A  39
ILE A  13
THR A  76
 None
 0.68A 3so9A-2a18A:
undetectable		 3so9A-2a18A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2a18 CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN
CCMK HOMOLOG 4
(Synechocystis
sp.
PCC
6803) 		5 / 9 ALA A  20
ILE A  48
LEU A  46
ILE A  33
ALA A  65
 None
 0.86A 5nunA-2a18A:
undetectable		 5nunA-2a18A:
22.69