SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 2a1d STAPHYLOCOAGULASE
(Staphylococcus
aureus) 		4 / 7 GLU D 187
LEU D 188
VAL D 171
LEU D 231
 None
 1.00A 1hk3A-2a1dD:
2.1		 1hk3A-2a1dD:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2a1d STAPHYLOCOAGULASE
(Staphylococcus
aureus) 		3 / 3 PRO D 202
ASP D 198
GLU D 199
 None
 0.82A 3v4tC-2a1dD:
undetectable		 3v4tC-2a1dD:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 2a1d STAPHYLOCOAGULASE
(Staphylococcus
aureus) 		4 / 8 ILE D  39
GLN D  37
THR D 122
GLU D  69
 None
 1.09A 6fbvC-2a1dD:
undetectable		 6fbvC-2a1dD:
15.14