SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 12 LEU A 116
LEU A  57
LEU A  41
CYH A  17
PHE A  19
 None
 1.49A 1a28A-2a33A:
0.0		 1a28A-2a33A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 8 PHE A 113
GLY A 143
LEU A 184
PHE A  19
 None
 1.05A 1gsfA-2a33A:
undetectable		 1gsfA-2a33A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 8 PHE A 113
GLY A 143
LEU A 184
PHE A  19
 None
 1.06A 1gsfB-2a33A:
undetectable		 1gsfB-2a33A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 8 PHE A 113
GLY A 143
LEU A 184
PHE A  19
 None
 1.06A 1gsfD-2a33A:
undetectable		 1gsfD-2a33A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 116
PRO A 117
LEU A  57
 None
 0.52A 1hrkA-2a33A:
2.6		 1hrkA-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 11 GLY A  56
GLY A  25
GLN A  24
GLY A 118
GLY A 119
 None
None
None
SO4  A 600 ( 3.8A)
SO4  A 600 (-3.6A)
 1.11A 1mxgA-2a33A:
undetectable		 1mxgA-2a33A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 THR A 122
LEU A 126
VAL A 129
 SO4  A 600 (-3.6A)
None
None
 0.45A 1mz9E-2a33A:
undetectable		 1mz9E-2a33A:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 7 GLY A 136
ILE A 137
VAL A 142
ILE A 174
 None
 0.60A 2aojB-2a33A:
undetectable		 2aojB-2a33A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 116
PRO A 117
LEU A  57
 None
 0.48A 2po5B-2a33A:
3.3		 2po5B-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 116
PRO A 117
LEU A  57
 None
 0.42A 2po7B-2a33A:
undetectable		 2po7B-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 116
PRO A 117
LEU A  57
 None
 0.30A 2qd5B-2a33A:
undetectable		 2qd5B-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ASP A 111
ILE A  16
LEU A  41
GLU A 189
 None
 1.02A 2ya7A-2a33A:
undetectable		 2ya7A-2a33A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ASP A 111
ILE A  16
LEU A  41
GLU A 189
 None
 1.00A 2ya7B-2a33A:
undetectable		 2ya7B-2a33A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		4 / 6 ASP A 111
ILE A  16
LEU A  41
GLU A 189
 None
 0.99A 2ya7D-2a33A:
undetectable		 2ya7D-2a33A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 9 ALA A 171
GLY A 136
ILE A 137
VAL A 142
ILE A 174
 None
 1.06A 3ekvB-2a33A:
undetectable		 3ekvB-2a33A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 116
PRO A 117
LEU A  57
 None
 0.40A 3hcrA-2a33A:
3.0		 3hcrA-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 LEU A 116
PRO A 117
LEU A  57
 None
 0.38A 3w1wB-2a33A:
3.0		 3w1wB-2a33A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ALA A 171
GLY A 136
ILE A 137
VAL A 142
ILE A 174
 None
 1.12A 4dqcA-2a33A:
undetectable		 4dqcA-2a33A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 8 LYS A 182
ALA A 181
GLY A  38
LEU A  37
LEU A 145
 None
 1.36A 4po0A-2a33A:
undetectable		 4po0A-2a33A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ALA A 171
GLY A 136
ILE A 137
VAL A 142
ILE A 174
 None
 1.06A 4q1wB-2a33A:
undetectable		 4q1wB-2a33A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 9 ALA A 171
GLY A 136
ILE A 137
VAL A 142
ILE A 174
 None
 1.13A 5kr0A-2a33A:
undetectable		 5kr0A-2a33A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		5 / 12 ILE A 158
VAL A 142
LEU A 154
LEU A 127
LEU A 123
 None
 1.18A 5tiwA-2a33A:
2.5		 5tiwA-2a33A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2a33 HYPOTHETICAL PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ARG A  15
HIS A  71
ARG A  94
 None
 0.97A 6dwdD-2a33A:
undetectable		 6dwdD-2a33A:
18.87