SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2a38 TITIN
(Homo
sapiens) 		3 / 3 ASN A 105
ALA A 102
ASN A 180
 None
 0.78A 1n4fA-2a38A:
undetectable		 1n4fA-2a38A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2a38 TITIN
(Homo
sapiens) 		5 / 8 ILE A 144
ILE A 163
PHE A 150
GLU A 190
LEU A 110
 None
 1.36A 3ua5A-2a38A:
undetectable		 3ua5A-2a38A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 2a38 TITIN
(Homo
sapiens) 		5 / 11 VAL A  37
ALA A  82
LEU A  80
ILE A  56
GLY A  61
 None
 0.94A 3zosA-2a38A:
undetectable
3zosB-2a38A:
undetectable		 3zosA-2a38A:
18.99
3zosB-2a38A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 2a38 TITIN
(Homo
sapiens) 		4 / 5 ARG A 139
PHE A 150
LEU A 161
LEU A 192
 None
 1.30A 5veuH-2a38A:
undetectable		 5veuH-2a38A:
16.42