SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DU8_B_BEZB1352_0 (D-AMINO-ACID OXIDASE)	2a3s	MYOCYTE NUCLEAR FACTOR (Mus musculus)	4 / 6	LEU A 11 TYR A 8 ILE A 29 GLY A 46	None	0.86A	2du8B-2a3sA: undetectable	2du8B-2a3sA: 14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFG_B_LEUB289_0 (GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT)	2a3s	MYOCYTE NUCLEAR FACTOR (Mus musculus)	3 / 3	PHE A 92 SER A 17 SER A 18	None	0.99A	3ufgB-2a3sA: undetectable	3ufgB-2a3sA: 15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_B_BZMB301_0 (ISATIN HYDROLASE A)	2a3s	MYOCYTE NUCLEAR FACTOR (Mus musculus)	5 / 12	ILE A 51 LEU A 11 ASP A 44 GLY A 46 TYR A 40	None	1.23A	5nnaB-2a3sA: undetectable	5nnaB-2a3sA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_C_BZMC301_0 (ISATIN HYDROLASE A)	2a3s	MYOCYTE NUCLEAR FACTOR (Mus musculus)	5 / 12	ILE A 51 LEU A 11 ASP A 44 GLY A 46 TYR A 40	None	1.21A	5nnaC-2a3sA: undetectable	5nnaC-2a3sA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	2a3s	MYOCYTE NUCLEAR FACTOR (Mus musculus)	4 / 7	ARG A 95 LEU A 11 GLN A 48 GLN A 90	None	1.26A	6b89A-2a3sA: undetectable	6b89A-2a3sA: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DU8_B_BEZB1352_0","D-AMINO-ACID OXIDASE","2a3s","MYOCYTE NUCLEAR FACTOR","Mus musculus",4,"LEU A  11;TYR A   8;ILE A  29;GLY A  46","None","0.86A","2du8B-2a3sA:undetectable","2du8B-2a3sA:14.07"],["3UFG_B_LEUB289_0","GLYCYL-TRNA SYNTHETASE ALPHA SUBUNIT","2a3s","MYOCYTE NUCLEAR FACTOR","Mus musculus",3,"PHE A  92;SER A  17;SER A  18","None","0.99A","3ufgB-2a3sA:undetectable","3ufgB-2a3sA:15.30"],["5NNA_B_BZMB301_0","ISATIN HYDROLASE A","2a3s","MYOCYTE NUCLEAR FACTOR","Mus musculus",5,"ILE A  51;LEU A  11;ASP A  44;GLY A  46;TYR A  40","None","1.23A","5nnaB-2a3sA:undetectable","5nnaB-2a3sA:13.33"],["5NNA_C_BZMC301_0","ISATIN HYDROLASE A","2a3s","MYOCYTE NUCLEAR FACTOR","Mus musculus",5,"ILE A  51;LEU A  11;ASP A  44;GLY A  46;TYR A  40","None","1.21A","5nnaC-2a3sA:undetectable","5nnaC-2a3sA:13.33"],["6B89_B_NOVB403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","2a3s","MYOCYTE NUCLEAR FACTOR","Mus musculus",4,"ARG A  95;LEU A  11;GLN A  48;GLN A  90","None","1.26A","6b89A-2a3sA:undetectable","6b89A-2a3sA:20.00"]]