SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		3 / 3 ILE A 111
LEU A 114
VAL A 118
 None
 0.40A 1mz9B-2a3vA:
undetectable		 1mz9B-2a3vA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		5 / 12 LEU A  83
THR A  31
ILE A  34
SER A   3
PHE A   5
 None
 1.21A 1xomB-2a3vA:
undetectable		 1xomB-2a3vA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		4 / 5 LEU A  54
LEU A  87
LEU A  89
LEU A  75
 None
 1.14A 1yajD-2a3vA:
undetectable		 1yajD-2a3vA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		5 / 9 LEU A 169
ARG A 270
LEU A 136
GLU A 138
GLY A 131
 None
 1.45A 3nxuB-2a3vA:
undetectable		 3nxuB-2a3vA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		3 / 3 TYR A  33
TYR A  79
GLU A  52
 None
 0.87A 3pfgA-2a3vA:
undetectable		 3pfgA-2a3vA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		4 / 5 LEU A  75
ILE A  34
PRO A  42
PHE A   5
 None
 1.21A 3s3vA-2a3vA:
undetectable		 3s3vA-2a3vA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 2a3v SITE-SPECIFIC
RECOMBINASE INTI4
(Vibrio
cholerae) 		5 / 11 ALA A  58
GLY A  61
LEU A  72
LEU A  75
PHE A  53
 None
 1.16A 4zmeA-2a3vA:
undetectable		 4zmeA-2a3vA:
21.18