SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a46'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.95A 1nodB-2a46A:
undetectable		 1nodB-2a46A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.93A 1qomA-2a46A:
undetectable		 1qomA-2a46A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.92A 2nodB-2a46A:
undetectable		 2nodB-2a46A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A 200
GLU A  39
SER A 148
 None
None
CR7  A  68 ( 2.5A)
 0.90A 2xkkA-2a46A:
undetectable
2xkkC-2a46A:
undetectable		 2xkkA-2a46A:
14.90
2xkkC-2a46A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.92A 3e7iB-2a46A:
undetectable		 3e7iB-2a46A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.96A 3nw2A-2a46A:
undetectable		 3nw2A-2a46A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.90A 3nw2B-2a46A:
undetectable		 3nw2B-2a46A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 PRO A 192
MET A 191
TYR A  84
 None
 0.80A 4qa0B-2a46A:
undetectable		 4qa0B-2a46A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 PRO A 192
MET A 191
TYR A  84
 None
 0.83A 4qa0A-2a46A:
undetectable		 4qa0A-2a46A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486
(Anemonia
majano) 		3 / 3 PRO A 192
MET A 191
TYR A  84
 None
 0.89A 4qa2B-2a46A:
undetectable		 4qa2B-2a46A:
21.37