SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		4 / 4 ILE A  64
MET A  52
VAL A   5
GLY A  49
 None
 1.21A 1e06B-2a5jA:
undetectable		 1e06B-2a5jA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		3 / 3 TRP A 105
THR A  67
TYR A  80
 None
 0.99A 2a3aA-2a5jA:
3.2		 2a3aA-2a5jA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		3 / 3 TRP A 105
THR A  67
TYR A  80
 None
 1.03A 2a3aB-2a5jA:
3.5		 2a3aB-2a5jA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		3 / 3 TRP A 105
THR A  67
TYR A  80
 None
 1.02A 2a3bA-2a5jA:
3.2		 2a3bA-2a5jA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		5 / 9 THR A 168
VAL A 161
THR A 153
VAL A  90
ILE A  16
 None
 1.34A 2l8mA-2a5jA:
undetectable		 2l8mA-2a5jA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		5 / 9 TYR A  14
THR A 168
THR A 153
VAL A  90
ILE A  16
 None
 1.36A 2l8mA-2a5jA:
undetectable		 2l8mA-2a5jA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		4 / 9 TYR A  14
PHE A  31
ILE A 122
MET A 151
 None
 1.10A 4jvlA-2a5jA:
undetectable		 4jvlA-2a5jA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2a5j RAS-RELATED PROTEIN
RAB-2B
(Homo
sapiens) 		5 / 12 PHE A  12
GLY A  86
ALA A  87
TYR A  10
GLN A 177
 None
 1.21A 4rtpA-2a5jA:
undetectable		 4rtpA-2a5jA:
25.78