SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a6c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 2a6c HELIX-TURN-HELIX
MOTIF
(Nitrosomonas
europaea) 		5 / 12 LEU A  11
LEU A  52
ILE A  56
ILE A  53
LEU A  39
 None
 1.03A 1xdkB-2a6cA:
undetectable		 1xdkB-2a6cA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 2a6c HELIX-TURN-HELIX
MOTIF
(Nitrosomonas
europaea) 		5 / 8 LYS A  24
ALA A  25
GLY A  30
LEU A  29
LEU A  15
 None
 1.40A 4po0A-2a6cA:
undetectable		 4po0A-2a6cA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2a6c HELIX-TURN-HELIX
MOTIF
(Nitrosomonas
europaea) 		3 / 3 LYS A  43
ASP A  45
ARG A  35
 None
 0.73A 5jwaA-2a6cA:
undetectable
5jwaH-2a6cA:
undetectable		 5jwaA-2a6cA:
8.70
5jwaH-2a6cA:
8.70