SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a74'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2a74 COMPLEMENT COMPONENT
C3C
(Homo
sapiens) 		5 / 11 ALA B 893
VAL B 864
GLY B 902
ILE B 809
VAL B 874
 GOL  B 701 (-3.5A)
None
None
None
None
 1.29A 2uxpB-2a74B:
undetectable		 2uxpB-2a74B:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 2a74 COMPLEMENT COMPONENT
C3C
(Homo
sapiens) 		5 / 9 ILE B 866
GLN B 805
ASP B 901
PHE B 807
LEU B 838
 None
 1.28A 3mjrA-2a74B:
undetectable		 3mjrA-2a74B:
22.85