SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a8e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 2a8e HYPOTHETICAL PROTEIN
YKTB
(Bacillus
subtilis) 		4 / 5 PHE A 196
PHE A  98
SER A 135
PHE A  75
 None
 1.28A 2v0mD-2a8eA:
undetectable		 2v0mD-2a8eA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2a8e HYPOTHETICAL PROTEIN
YKTB
(Bacillus
subtilis) 		5 / 12 GLN A 207
PHE A 201
ALA A 200
THR A 206
GLY A  50
 None
 1.38A 3aodC-2a8eA:
undetectable		 3aodC-2a8eA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2a8e HYPOTHETICAL PROTEIN
YKTB
(Bacillus
subtilis) 		4 / 7 THR A 206
VAL A 209
THR A 210
ILE A 109
 None
 0.41A 3deuA-2a8eA:
undetectable		 3deuA-2a8eA:
24.02