SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a8g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 2a8g AVIDIN
(Gallus
gallus) 		5 / 7 ASN A  12
LEU A  14
SER A  16
TYR A  33
THR A  35
 None
 0.64A 2uz2A-2a8gA:
19.4		 2uz2A-2a8gA:
54.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_C_CLMC221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2a8g AVIDIN
(Gallus
gallus) 		5 / 11 PHE A  79
PHE A 120
SER A  16
TYR A  33
VAL A 115
 None
 1.45A 3u9fA-2a8gA:
0.0
3u9fC-2a8gA:
0.0		 3u9fA-2a8gA:
18.84
3u9fC-2a8gA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 2a8g AVIDIN
(Gallus
gallus) 		4 / 8 LEU A  49
LEU A   6
ILE A 117
THR A  95
 None
 1.04A 5ljbA-2a8gA:
3.2		 5ljbA-2a8gA:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LUR_A_STRA201_1
(AVIDIN)		 2a8g AVIDIN
(Gallus
gallus) 		7 / 10 TYR A  33
TRP A  70
PHE A  72
THR A  77
PHE A  79
TRP A  97
ASN A 118
 None
 0.29A 5lurA-2a8gA:
21.8		 5lurA-2a8gA:
92.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LUR_A_STRA201_1
(AVIDIN)		 2a8g AVIDIN
(Gallus
gallus) 		6 / 10 TYR A  33
VAL A  37
THR A  77
PHE A  79
TRP A  97
ASN A 118
 None
 0.74A 5lurA-2a8gA:
21.8		 5lurA-2a8gA:
92.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LUR_B_STRB201_1
(AVIDIN)		 2a8g AVIDIN
(Gallus
gallus) 		5 / 11 TYR A  33
VAL A  37
TRP A  70
PHE A  72
ASN A  12
 None
 1.24A 5lurB-2a8gA:
21.4		 5lurB-2a8gA:
92.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LUR_B_STRB201_1
(AVIDIN)		 2a8g AVIDIN
(Gallus
gallus) 		8 / 11 TYR A  33
VAL A  37
TRP A  70
PHE A  72
THR A  77
PHE A  79
TRP A  97
ASN A 118
 None
 0.48A 5lurB-2a8gA:
21.4		 5lurB-2a8gA:
92.06