SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2a8k COLICIN E5
(Escherichia
coli) 		4 / 6 ARG A  60
ASP A  62
THR A  80
ASP A  56
 None
 1.25A 2j2pE-2a8kA:
undetectable
2j2pF-2a8kA:
undetectable		 2j2pE-2a8kA:
18.30
2j2pF-2a8kA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2C_A_ACTA153_0
(N UTILIZATION
SUBSTANCE PROTEIN B)		 2a8k COLICIN E5
(Escherichia
coli) 		4 / 4 ASN A  77
GLY A  81
GLU A  82
LYS A  13
 None
 1.11A 3r2cA-2a8kA:
undetectable		 3r2cA-2a8kA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.62A 5qgjA-2a8kA:
undetectable		 5qgjA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.64A 5qglA-2a8kA:
undetectable		 5qglA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.66A 5qgmA-2a8kA:
undetectable		 5qgmA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.63A 5qgnA-2a8kA:
undetectable		 5qgnA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.66A 5qguA-2a8kA:
undetectable		 5qguA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.71A 5qgvA-2a8kA:
undetectable		 5qgvA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.71A 5qgxA-2a8kA:
undetectable		 5qgxA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.73A 5qh1A-2a8kA:
undetectable		 5qh1A-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.67A 5qh4A-2a8kA:
undetectable		 5qh4A-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.68A 5qh9A-2a8kA:
undetectable		 5qh9A-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.66A 5qhcA-2a8kA:
undetectable		 5qhcA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.69A 5qheA-2a8kA:
undetectable		 5qheA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.71A 5qhfA-2a8kA:
undetectable		 5qhfA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.66A 5qhgA-2a8kA:
undetectable		 5qhgA-2a8kA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2a8k COLICIN E5
(Escherichia
coli) 		3 / 3 VAL A  75
VAL A  66
GLN A 101
 None
 0.68A 5qhhA-2a8kA:
undetectable		 5qhhA-2a8kA:
21.03