SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 2a90 DELTEX PROTEIN
(Drosophila
melanogaster) 		5 / 10 ILE A 157
SER A 171
ASN A 172
GLU A 165
ARG A 163
 None
 1.26A 3u6tA-2a90A:
undetectable		 3u6tA-2a90A:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 2a90 DELTEX PROTEIN
(Drosophila
melanogaster) 		3 / 3 TYR A 121
GLN A 204
TRP A  49
 None
 1.11A 4kn2C-2a90A:
undetectable		 4kn2C-2a90A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 2a90 DELTEX PROTEIN
(Drosophila
melanogaster) 		5 / 12 ALA A 160
LEU A 170
ASN A 182
PHE A 183
ILE A 199
 None
 1.34A 4pb1A-2a90A:
undetectable		 4pb1A-2a90A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 2a90 DELTEX PROTEIN
(Drosophila
melanogaster) 		5 / 12 ALA A 160
LEU A 170
PHE A 183
ASN A 185
ILE A 199
 None
 1.09A 4pb1A-2a90A:
undetectable		 4pb1A-2a90A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 2a90 DELTEX PROTEIN
(Drosophila
melanogaster) 		5 / 12 ALA A 160
LEU A 170
PHE A 183
ASN A 185
ILE A 199
 None
 1.12A 4pd5A-2a90A:
undetectable		 4pd5A-2a90A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 2a90 DELTEX PROTEIN
(Drosophila
melanogaster) 		3 / 3 ARG A 200
LYS A 132
GLU A 134
 None
 0.73A 5d0yA-2a90A:
undetectable		 5d0yA-2a90A:
21.31