SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2a9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.01A 1zzrA-2a9mL:
undetectable
1zzrB-2a9mL:
undetectable		 1zzrA-2a9mL:
13.81
1zzrB-2a9mL:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.02A 1zzrA-2a9mL:
undetectable
1zzrB-2a9mL:
undetectable		 1zzrA-2a9mL:
13.81
1zzrB-2a9mL:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.01A 1zzuA-2a9mL:
undetectable
1zzuB-2a9mL:
undetectable		 1zzuA-2a9mL:
13.81
1zzuB-2a9mL:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.01A 1zzuA-2a9mL:
undetectable
1zzuB-2a9mL:
undetectable		 1zzuA-2a9mL:
13.81
1zzuB-2a9mL:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 8 SER L 135
TRP L 109
SER H 134
LEU L 138
 None
 0.97A 2cdqA-2a9mL:
undetectable		 2cdqA-2a9mL:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 SER L 135
TRP L 109
SER H 134
LEU L 138
 None
 0.98A 2cdqB-2a9mL:
undetectable		 2cdqB-2a9mL:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR H 105
TYR L  44
PRO L  52
TYR L 105
 None
 0.71A 2oldA-2a9mH:
13.8
2oldB-2a9mH:
13.8		 2oldA-2a9mH:
23.50
2oldB-2a9mH:
23.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 TYR L  44
PRO L  52
TYR L 105
TYR H 105
 None
 0.66A 2oldA-2a9mL:
21.1
2oldB-2a9mL:
21.2		 2oldA-2a9mL:
64.86
2oldB-2a9mL:
64.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.03A 3dqrA-2a9mL:
undetectable
3dqrB-2a9mL:
undetectable		 3dqrA-2a9mL:
13.74
3dqrB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens;
Homo
sapiens) 		4 / 7 PHE L 137
PHE L 139
SER L  42
TYR H 135
 None
 1.36A 3hggA-2a9mL:
undetectable		 3hggA-2a9mL:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 0.98A 3jx2A-2a9mL:
undetectable
3jx2B-2a9mL:
undetectable		 3jx2A-2a9mL:
13.74
3jx2B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.00A 3jx2A-2a9mL:
undetectable
3jx2B-2a9mL:
undetectable		 3jx2A-2a9mL:
13.74
3jx2B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.04A 3jx3A-2a9mL:
undetectable
3jx3B-2a9mL:
undetectable		 3jx3A-2a9mL:
13.74
3jx3B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.00A 3jx3A-2a9mL:
undetectable
3jx3B-2a9mL:
undetectable		 3jx3A-2a9mL:
13.74
3jx3B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.02A 3jx4A-2a9mL:
undetectable
3jx4B-2a9mL:
undetectable		 3jx4A-2a9mL:
13.74
3jx4B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.00A 3jx5A-2a9mL:
undetectable
3jx5B-2a9mL:
undetectable		 3jx5A-2a9mL:
13.74
3jx5B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.01A 3jx5A-2a9mL:
undetectable
3jx5B-2a9mL:
undetectable		 3jx5A-2a9mL:
13.74
3jx5B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 0.94A 3jx6A-2a9mL:
undetectable
3jx6B-2a9mL:
undetectable		 3jx6A-2a9mL:
13.74
3jx6B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 0.97A 3jx6A-2a9mL:
undetectable
3jx6B-2a9mL:
undetectable		 3jx6A-2a9mL:
13.74
3jx6B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 0.94A 3nljA-2a9mL:
undetectable
3nljB-2a9mL:
undetectable		 3nljA-2a9mL:
13.74
3nljB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 0.96A 3nljA-2a9mL:
undetectable
3nljB-2a9mL:
undetectable		 3nljA-2a9mL:
13.74
3nljB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 0.98A 3nlpA-2a9mL:
undetectable
3nlpB-2a9mL:
undetectable		 3nlpA-2a9mL:
13.74
3nlpB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.01A 3nlpA-2a9mL:
undetectable
3nlpB-2a9mL:
undetectable		 3nlpA-2a9mL:
13.74
3nlpB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 8 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 0.94A 3nlqA-2a9mL:
undetectable
3nlqB-2a9mL:
undetectable		 3nlqA-2a9mL:
13.74
3nlqB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 0.98A 3nlqA-2a9mL:
undetectable
3nlqB-2a9mL:
undetectable		 3nlqA-2a9mL:
13.74
3nlqB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 0.99A 3nlrA-2a9mL:
undetectable
3nlrB-2a9mL:
undetectable		 3nlrA-2a9mL:
13.74
3nlrB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 8 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.00A 3nlrA-2a9mL:
undetectable
3nlrB-2a9mL:
undetectable		 3nlrA-2a9mL:
13.74
3nlrB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 PHE L  78
MET L  55
ILE L  21
VAL L  19
 None
 0.96A 3p6hA-2a9mL:
undetectable		 3p6hA-2a9mL:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 LEU H   4
ASN H  87
PHE H  29
ARG H 109
VAL H  89
 None
 1.39A 4b3aA-2a9mH:
undetectable		 4b3aA-2a9mH:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
(Homo
sapiens) 		5 / 12 LEU H   4
SER H  88
ASN H  87
PHE H  29
ARG H 109
 None
 1.49A 4b3aA-2a9mH:
undetectable		 4b3aA-2a9mH:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.03A 4cx3A-2a9mL:
undetectable
4cx3B-2a9mL:
undetectable		 4cx3A-2a9mL:
13.74
4cx3B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.01A 4cx3A-2a9mL:
undetectable
4cx3B-2a9mL:
undetectable		 4cx3A-2a9mL:
13.74
4cx3B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.03A 4cx4A-2a9mL:
undetectable
4cx4B-2a9mL:
undetectable		 4cx4A-2a9mL:
13.74
4cx4B-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.01A 4cx4A-2a9mL:
undetectable
4cx4B-2a9mL:
undetectable		 4cx4A-2a9mL:
13.74
4cx4B-2a9mL:
13.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 TYR H 133
TYR L  44
TYR L  57
PRO L  71
 None
 0.82A 5aclA-2a9mH:
14.3		 5aclA-2a9mH:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 TYR L  40
TYR L  44
TYR L  57
PRO L  71
 None
 0.87A 5aclA-2a9mL:
21.2		 5aclA-2a9mL:
70.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 0.96A 5addA-2a9mL:
undetectable
5addB-2a9mL:
undetectable		 5addA-2a9mL:
13.74
5addB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 0.95A 5adeA-2a9mL:
undetectable
5adeB-2a9mL:
undetectable		 5adeA-2a9mL:
13.74
5adeB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 VAL L 147
ARG L  77
VAL L  19
GLU L 101
 None
 1.01A 5g0pA-2a9mL:
undetectable
5g0pB-2a9mL:
undetectable		 5g0pA-2a9mL:
13.74
5g0pB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2a9m FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLU L 101
VAL L 147
ARG L  77
VAL L  19
 None
 1.02A 5g0pA-2a9mL:
undetectable
5g0pB-2a9mL:
undetectable		 5g0pA-2a9mL:
13.74
5g0pB-2a9mL:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
FLUORESCEIN-SCFV
LIGHT CHAIN
(Homo
sapiens) 		4 / 7 LEU L 138
TRP H  54
VAL H  74
SER H  73
 None
 1.16A 5umwA-2a9mL:
undetectable
5umwF-2a9mL:
undetectable		 5umwA-2a9mL:
18.18
5umwF-2a9mL:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 SER H 113
SER H 134
ALA H 107
 None
 0.52A 6dwnC-2a9mH:
undetectable		 6dwnC-2a9mH:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 2a9m FLUORESCEIN-SCFV
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 SER H 114
SER H 113
ALA H 107
 None
 0.69A 6dwnC-2a9mH:
undetectable		 6dwnC-2a9mH:
21.43