SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aaa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		7 / 12 HIS A  80
TYR A  82
LEU A 173
ASP A 206
HIS A 296
ASP A 297
ARG A 344
 None
None
None
CA  A 486 (-3.0A)
None
CA  A 486 ( 4.6A)
None
 0.65A 1dedA-2aaaA:
41.0		 1dedA-2aaaA:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		6 / 12 HIS A  80
TYR A  82
LEU A 173
GLU A 230
ASP A 297
ARG A 344
 None
None
None
CA  A 486 (-2.5A)
CA  A 486 ( 4.6A)
None
 1.07A 1dedA-2aaaA:
41.0		 1dedA-2aaaA:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		9 / 12 HIS A  80
TYR A  82
LEU A 173
ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
ARG A 344
 None
None
None
CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
None
 0.72A 1dedB-2aaaA:
40.0		 1dedB-2aaaA:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 7 TRP A 348
SER A  25
ASP A  23
PHE A  19
 None
 1.16A 1ismB-2aaaA:
undetectable		 1ismB-2aaaA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		7 / 12 TYR A  82
HIS A 122
ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 None
None
CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.33A 1mxdA-2aaaA:
31.4		 1mxdA-2aaaA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 6 TYR A 255
GLY A 267
PHE A 262
SER A 264
 None
 1.31A 2a3cA-2aaaA:
9.5		 2a3cA-2aaaA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 6 TYR A 255
GLY A 267
PHE A 262
SER A 264
 None
 1.36A 2a3cB-2aaaA:
9.3		 2a3cB-2aaaA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 LEU A 194
ILE A  87
THR A  16
VAL A 116
LEU A 103
 None
 1.11A 2g78A-2aaaA:
undetectable		 2g78A-2aaaA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 11 LEU A 100
LEU A 103
LEU A 107
ILE A  65
TRP A   6
 None
 0.98A 2qd3A-2aaaA:
undetectable		 2qd3A-2aaaA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 PRO A 341
GLY A  33
TYR A 342
 None
 0.65A 2vouA-2aaaA:
undetectable		 2vouA-2aaaA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 PRO A 341
GLY A  33
TYR A 342
 None
 0.65A 2vouB-2aaaA:
undetectable		 2vouB-2aaaA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 PRO A 341
GLY A  33
TYR A 342
 None
 0.65A 2vouC-2aaaA:
undetectable		 2vouC-2aaaA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ASP A 206
PHE A 292
ASN A 298
TYR A 252
ASP A 297
 CA  A 486 (-3.0A)
None
None
None
CA  A 486 ( 4.6A)
 1.33A 2x2iA-2aaaA:
12.0		 2x2iA-2aaaA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.66A 3aicA-2aaaA:
2.0		 3aicA-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.64A 3aicB-2aaaA:
9.4		 3aicB-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		6 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
TYR A  82
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
None
 0.69A 3aicC-2aaaA:
3.6		 3aicC-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.75A 3aicD-2aaaA:
9.6		 3aicD-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.69A 3aicE-2aaaA:
9.5		 3aicE-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.67A 3aicF-2aaaA:
9.5		 3aicF-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.65A 3aicG-2aaaA:
9.6		 3aicG-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.72A 3aicH-2aaaA:
9.6		 3aicH-2aaaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		6 / 12 LEU A 250
TYR A  82
ILE A  62
ILE A  11
VAL A 228
ASP A 117
 None
 1.38A 3bwcB-2aaaA:
undetectable		 3bwcB-2aaaA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 TYR A 352
TYR A  12
ILE A  52
 None
 0.69A 3eteA-2aaaA:
undetectable
3eteB-2aaaA:
undetectable		 3eteA-2aaaA:
22.78
3eteB-2aaaA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 VAL A  90
LEU A 107
LEU A 114
ILE A  62
ILE A  52
 None
 0.99A 3gcsA-2aaaA:
undetectable		 3gcsA-2aaaA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 GLU A 230
ASP A 117
ASP A 121
 CA  A 486 (-2.5A)
None
CA  A 485 (-3.2A)
 0.66A 3jb2A-2aaaA:
undetectable		 3jb2A-2aaaA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 HIS A 122
PHE A 215
PHE A 216
 None
 0.70A 3lk0D-2aaaA:
undetectable		 3lk0D-2aaaA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 TYR A  37
LEU A  15
PHE A  94
PHE A  13
ASN A  91
 None
 1.42A 3nuvA-2aaaA:
1.5		 3nuvA-2aaaA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 5 SER A 401
ILE A 406
TYR A 382
GLY A 427
 None
 0.97A 3uboB-2aaaA:
4.2		 3uboB-2aaaA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 SER A 278
ASP A 239
ASP A 232
 None
 0.76A 3uj7A-2aaaA:
undetectable		 3uj7A-2aaaA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 LEU A 100
LEU A 103
LEU A 107
ILE A  65
TRP A   6
 None
 0.94A 4f4dB-2aaaA:
undetectable		 4f4dB-2aaaA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 8 LEU A 100
LEU A 103
LEU A 107
ILE A  65
 None
 0.84A 4klaA-2aaaA:
undetectable		 4klaA-2aaaA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 SER A 278
ASP A 239
ASP A 232
 None
 0.70A 4mwzA-2aaaA:
undetectable		 4mwzA-2aaaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 ASP A 307
LEU A 459
GLY A 458
 None
 0.57A 4xmfA-2aaaA:
undetectable		 4xmfA-2aaaA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 7 ALA A 182
ASP A 214
THR A 159
GLU A 162
 None
 0.80A 5bs8A-2aaaA:
undetectable
5bs8C-2aaaA:
undetectable
5bs8D-2aaaA:
undetectable		 5bs8A-2aaaA:
22.85
5bs8C-2aaaA:
22.85
5bs8D-2aaaA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 7 ALA A 182
ASP A 214
THR A 159
GLU A 162
 None
 0.80A 5btgA-2aaaA:
undetectable
5btgC-2aaaA:
undetectable
5btgD-2aaaA:
undetectable		 5btgA-2aaaA:
22.85
5btgC-2aaaA:
22.85
5btgD-2aaaA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 ARG A 204
ASP A 206
GLU A 230
HIS A 296
ASP A 297
 CA  A 486 ( 4.5A)
CA  A 486 (-3.0A)
CA  A 486 (-2.5A)
None
CA  A 486 ( 4.6A)
 0.46A 5csyB-2aaaA:
19.1		 5csyB-2aaaA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 TYR A  51
TYR A 335
GLN A 333
 None
 1.02A 5jsdA-2aaaA:
undetectable
5jsdB-2aaaA:
undetectable		 5jsdA-2aaaA:
23.86
5jsdB-2aaaA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 TYR A  51
TYR A 335
GLN A 333
 None
 1.00A 5jsdB-2aaaA:
undetectable
5jsdC-2aaaA:
undetectable		 5jsdB-2aaaA:
23.86
5jsdC-2aaaA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		3 / 3 LEU A 371
ALA A 367
LEU A 464
 None
 0.54A 5uunB-2aaaA:
undetectable		 5uunB-2aaaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 12 TYR A  82
HIS A 122
ASP A 206
HIS A 296
ASP A 297
 None
None
CA  A 486 (-3.0A)
None
CA  A 486 ( 4.6A)
 0.51A 6ag0A-2aaaA:
26.5		 6ag0A-2aaaA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		5 / 11 PHE A 262
LEU A 258
SER A 268
GLY A 267
ILE A 394
 None
 1.07A 6ebzC-2aaaA:
undetectable		 6ebzC-2aaaA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2aaa ALPHA-AMYLASE
(Aspergillus
niger) 		4 / 8 ASP A 121
HIS A 296
GLU A 230
ASP A 232
 CA  A 485 (-3.2A)
None
CA  A 486 (-2.5A)
None
 1.09A 6mn4D-2aaaA:
undetectable		 6mn4D-2aaaA:
20.67