SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.37A 1oe1A-2aanA:
5.0		 1oe1A-2aanA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 5 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.36A 1oe2A-2aanA:
8.3		 1oe2A-2aanA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.39A 1oe3A-2aanA:
6.0		 1oe3A-2aanA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.41A 2fqdA-2aanA:
4.0		 2fqdA-2aanA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.38A 2fqeA-2aanA:
3.7		 2fqeA-2aanA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.35A 2fqfA-2aanA:
3.7		 2fqfA-2aanA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.37A 2fqgA-2aanA:
3.7		 2fqgA-2aanA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.37A 2xxgA-2aanA:
9.7		 2xxgA-2aanA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 5 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.38A 2xxgC-2aanA:
9.7		 2xxgC-2aanA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 7 PRO A  88
GLY A  77
ALA A  76
ALA A  71
 None
 0.77A 3ur0B-2aanA:
undetectable		 3ur0B-2aanA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		5 / 9 ALA A  80
LEU A  87
LEU A 100
ASN A  59
ILE A  61
 None
 1.30A 3wdmA-2aanA:
undetectable		 3wdmA-2aanA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		4 / 4 HIS A  58
CYH A 123
HIS A 128
MET A 132
 CU  A 140 (-3.1A)
CU  A 140 (-2.2A)
CU  A 140 (-3.1A)
CU  A 140 (-2.9A)
 0.35A 4ef3A-2aanA:
3.7		 4ef3A-2aanA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		5 / 12 GLY A  66
ILE A 122
ASN A  93
VAL A  63
LEU A  62
 None
 0.98A 4fr0A-2aanA:
undetectable		 4fr0A-2aanA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 2aan AURACYANIN A
(Chloroflexus
aurantiacus) 		5 / 8 VAL A 138
LEU A 136
ILE A  23
VAL A 109
THR A 110
 None
 1.16A 4ma7A-2aanA:
undetectable		 4ma7A-2aanA:
16.67