SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2abk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 2abk ENDONUCLEASE III
(Escherichia
coli) 		4 / 5 PRO A  29
LEU A  32
THR A 134
ARG A 108
 None
 1.25A 1i2wA-2abkA:
undetectable		 1i2wA-2abkA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 2abk ENDONUCLEASE III
(Escherichia
coli) 		4 / 7 THR A  22
HIS A 176
ASN A 127
PHE A  26
 None
 1.30A 4awuA-2abkA:
undetectable		 4awuA-2abkA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)		 2abk ENDONUCLEASE III
(Escherichia
coli) 		4 / 7 VAL A 125
ALA A 129
LEU A  37
ASP A 107
 None
 0.82A 4l9iA-2abkA:
undetectable		 4l9iA-2abkA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 2abk ENDONUCLEASE III
(Escherichia
coli) 		4 / 7 ASP A 138
ILE A 180
GLY A 183
THR A 139
 None
 0.94A 4zxiA-2abkA:
undetectable		 4zxiA-2abkA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 2abk ENDONUCLEASE III
(Escherichia
coli) 		3 / 3 GLU A 160
HIS A 176
VAL A 137
 None
 0.85A 5trqB-2abkA:
undetectable		 5trqB-2abkA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 2abk ENDONUCLEASE III
(Escherichia
coli) 		5 / 12 PHE A 130
ALA A  35
THR A  92
LEU A  96
LEU A 111
 None
 1.18A 6aybA-2abkA:
undetectable		 6aybA-2abkA:
19.09