SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2abl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_A_NCAA1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	2abl	ABL TYROSINE KINASE (Homo sapiens)	4 / 7	ARG A 171 SER A 152 ARG A 194 GLU A 174	None	1.32A	2c8aA-2ablA: undetectable	2c8aA-2ablA: 25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_C_NCAC1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	2abl	ABL TYROSINE KINASE (Homo sapiens)	4 / 6	ARG A 171 SER A 152 ARG A 194 GLU A 174	None	1.31A	2c8aC-2ablA: undetectable	2c8aC-2ablA: 25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_C_NCAC1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	2abl	ABL TYROSINE KINASE (Homo sapiens)	4 / 6	ARG A 171 SER A 152 SER A 173 GLU A 174	None	1.39A	2c8aC-2ablA: undetectable	2c8aC-2ablA: 25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1498_1 (CYTOCHROME P450 3A4)	2abl	ABL TYROSINE KINASE (Homo sapiens)	5 / 11	SER A 206 ALA A 225 THR A 231 ARG A 171 LEU A 184	None	1.38A	2v0mD-2ablA: undetectable	2v0mD-2ablA: 13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC608_1 (ALPHA-AMYLASE)	2abl	ABL TYROSINE KINASE (Homo sapiens)	3 / 3	TYR A 193 ALA A 156 LEU A 160	None	0.59A	6ag0C-2ablA: undetectable	6ag0C-2ablA: 20.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C8A_A_NCAA1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","2abl","ABL TYROSINE KINASE","Homo sapiens",4,"ARG A 171;SER A 152;ARG A 194;GLU A 174","None","1.32A","2c8aA-2ablA:undetectable","2c8aA-2ablA:25.11"],["2C8A_C_NCAC1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","2abl","ABL TYROSINE KINASE","Homo sapiens",4,"ARG A 171;SER A 152;ARG A 194;GLU A 174","None","1.31A","2c8aC-2ablA:undetectable","2c8aC-2ablA:25.11"],["2C8A_C_NCAC1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","2abl","ABL TYROSINE KINASE","Homo sapiens",4,"ARG A 171;SER A 152;SER A 173;GLU A 174","None","1.39A","2c8aC-2ablA:undetectable","2c8aC-2ablA:25.11"],["2V0M_D_KLND1498_1","CYTOCHROME P450 3A4","2abl","ABL TYROSINE KINASE","Homo sapiens",5,"SER A 206;ALA A 225;THR A 231;ARG A 171;LEU A 184","None","1.38A","2v0mD-2ablA:undetectable","2v0mD-2ablA:13.66"],["6AG0_C_ACRC608_1","ALPHA-AMYLASE","2abl","ABL TYROSINE KINASE","Homo sapiens",3,"TYR A 193;ALA A 156;LEU A 160","None","0.59A","6ag0C-2ablA:undetectable","6ag0C-2ablA:20.53"]]