SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2acm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 2acm MUCIN-1
(Homo
sapiens) 		4 / 6 LEU A1069
ILE B1136
TYR B1132
VAL B1101
 None
 1.11A 1db1A-2acmA:
undetectable		 1db1A-2acmA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 2acm MUCIN-1
(Homo
sapiens) 		4 / 6 PRO A1061
PHE A1077
LEU A1089
ILE A1092
 None
 1.22A 1sbrA-2acmA:
undetectable
1sbrB-2acmA:
undetectable		 1sbrA-2acmA:
17.44
1sbrB-2acmA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2acm MUCIN-1
(Homo
sapiens) 		3 / 3 TYR A1066
ASP A1064
GLN A1067
 None
 0.92A 6g1pA-2acmA:
undetectable		 6g1pA-2acmA:
10.85