SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.02A 1t87A-2acoA:
undetectable		 1t87A-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 5 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.05A 1t88B-2acoA:
undetectable		 1t88B-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.04A 1yrcA-2acoA:
undetectable		 1yrcA-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.02A 1yrdA-2acoA:
undetectable		 1yrdA-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.08A 2cppA-2acoA:
undetectable		 2cppA-2acoA:
18.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		5 / 7 ALA A  62
TYR A  64
ASN A  76
TRP A 139
LEU A 141
 None
 1.08A 2hzqA-2acoA:
20.0		 2hzqA-2acoA:
31.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 0.91A 2z97A-2acoA:
undetectable		 2z97A-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 0.99A 2zawA-2acoA:
undetectable		 2zawA-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.04A 2zaxA-2acoA:
undetectable		 2zaxA-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 0.97A 2zuhA-2acoA:
undetectable		 2zuhA-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.02A 2zuiA-2acoA:
undetectable		 2zuiA-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.03A 2zwtA-2acoA:
undetectable		 2zwtA-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.03A 2zwuA-2acoA:
undetectable		 2zwuA-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.08A 3fwgB-2acoA:
undetectable		 3fwgB-2acoA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 7 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.06A 3fwjA-2acoA:
undetectable		 3fwjA-2acoA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		5 / 12 ALA A 159
PHE A 164
ALA A 120
THR A  14
VAL A  28
 None
 0.99A 3rukA-2acoA:
undetectable		 3rukA-2acoA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.07A 3wrhE-2acoA:
undetectable		 3wrhE-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.09A 3wrjE-2acoA:
undetectable		 3wrjE-2acoA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.10A 4g3rA-2acoA:
undetectable		 4g3rA-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.08A 4g3rB-2acoA:
undetectable		 4g3rB-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.08A 4kkyX-2acoA:
undetectable		 4kkyX-2acoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 8 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.01A 4l4aA-2acoA:
undetectable		 4l4aA-2acoA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		4 / 6 TYR A  39
LEU A 141
VAL A 130
VAL A 106
 None
 1.10A 4l4cA-2acoA:
undetectable		 4l4cA-2acoA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		5 / 9 PHE A 169
ASN A 117
ILE A 119
VAL A 118
GLY A 132
 None
 1.29A 4r20B-2acoA:
undetectable		 4r20B-2acoA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		5 / 12 ASP A  35
ALA A  36
LYS A  19
PHE A  95
THR A  23
 None
 1.34A 5hfjC-2acoA:
undetectable		 5hfjC-2acoA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		5 / 12 ASP A  35
ALA A  36
LYS A  19
PHE A  95
THR A  23
 None
 1.39A 5hfjH-2acoA:
undetectable		 5hfjH-2acoA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		3 / 3 TYR A 116
ALA A  62
LEU A 141
 None
 0.70A 6d9kF-2acoA:
undetectable		 6d9kF-2acoA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 2aco OUTER MEMBRANE
LIPOPROTEIN BLC
(Escherichia
coli) 		3 / 3 TYR A 137
HIS A  51
PHE A  53
 None
 0.93A 6esmA-2acoA:
undetectable		 6esmA-2acoA:
16.67