SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2adv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 7 LEU B  24
HIS C 453
THR C  67
ASN C 244
 None
 1.17A 1afsA-2advB:
undetectable		 1afsA-2advB:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 7 LEU B  24
HIS C 453
THR C  67
ASN C 244
 None
 1.17A 1afsB-2advB:
undetectable		 1afsB-2advB:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 11 GLU C  35
LEU C 472
ARG C 499
GLY C 454
HIS B  23
 None
 1.28A 1g50C-2advC:
undetectable		 1g50C-2advC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 6 ALA C 345
ARG C 415
LEU C 346
TRP C 440
 None
 1.18A 1gahA-2advC:
undetectable		 1gahA-2advC:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 8 LEU C 226
SER C 191
ASN C 189
THR C  67
 None
 1.12A 1ig3A-2advC:
undetectable
1ig3B-2advC:
undetectable		 1ig3A-2advC:
18.75
1ig3B-2advC:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1;
Pseudomonas
sp.
SY-77-1) 		3 / 3 ALA C 182
VAL B   6
TRP B   4
 None
 0.99A 1tkqA-2advC:
undetectable		 1tkqA-2advC:
2.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 12 LEU C 432
GLU C 349
ARG C 353
GLY C 454
HIS B  23
 None
 1.24A 2j7xA-2advC:
undetectable		 2j7xA-2advC:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 5 ALA C 395
ALA C 316
ALA C 315
VAL C 382
 None
 0.93A 2nyrB-2advC:
undetectable		 2nyrB-2advC:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 ASP C 420
THR C 450
PRO C 451
 None
 0.61A 2pynB-2advC:
undetectable		 2pynB-2advC:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 ASP C 420
THR C 450
PRO C 451
 None
 0.57A 2q64B-2advC:
undetectable		 2q64B-2advC:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 ASP C 420
THR C 450
PRO C 451
 None
 0.64A 2qakB-2advC:
undetectable		 2qakB-2advC:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 8 ARG C 146
PRO C 127
SER C 122
VAL C 141
 None
 1.12A 2qd2A-2advC:
undetectable		 2qd2A-2advC:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 8 GLY C 428
ALA C 427
GLY C 411
VAL C 493
 None
 0.63A 3em6A-2advC:
undetectable		 3em6A-2advC:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 12 GLY C 213
LEU C 219
LEU C  83
GLY C 126
SER C 123
 None
 1.11A 3g2oB-2advC:
undetectable		 3g2oB-2advC:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 4 ILE C  45
ARG C 171
ILE C 157
THR C  40
 None
 1.29A 3ia4C-2advC:
undetectable		 3ia4C-2advC:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 12 GLY C 476
PHE C 498
ARG C 492
ALA C 496
ASP C 497
 None
 1.14A 3keeA-2advC:
undetectable		 3keeA-2advC:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 12 GLY C 476
PHE C 498
ARG C 492
ALA C 496
ASP C 497
 None
 1.12A 3keeD-2advC:
undetectable		 3keeD-2advC:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1;
Pseudomonas
sp.
SY-77-1) 		4 / 6 PHE C 438
HIS B  23
THR C 456
VAL C 458
 None
 1.17A 3lb3B-2advC:
undetectable		 3lb3B-2advC:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 8 THR C  49
GLY C  47
GLN B  20
ILE C 157
 None
 0.95A 3nbqB-2advC:
undetectable		 3nbqB-2advC:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 8 THR C  49
GLY C  47
GLN B  20
ILE C 157
 None
 0.93A 3nbqC-2advC:
undetectable		 3nbqC-2advC:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 ASP C 420
THR C 450
PRO C 451
 None
 0.50A 3tkgD-2advC:
undetectable		 3tkgD-2advC:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 LYS C 116
PRO C 117
LEU C 118
 None
 0.74A 3tpxE-2advC:
undetectable		 3tpxE-2advC:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 11 GLU C  35
LEU C 472
ARG C 499
GLY C 454
HIS B  23
 None
 1.25A 3uudA-2advC:
undetectable		 3uudA-2advC:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 10 ALA C 332
LEU C 331
ILE C 396
ALA C 395
ALA C 388
 None
 1.01A 4j14A-2advC:
undetectable		 4j14A-2advC:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 ASP C 444
LYS C 402
LEU C 346
 None
 0.75A 4ptjA-2advC:
undetectable		 4ptjA-2advC:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 11 LEU C 432
GLU C 349
ARG C 353
GLY C 454
HIS B  23
 None
 1.23A 4pxmB-2advC:
undetectable		 4pxmB-2advC:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 GLU C 514
THR C 484
HIS C 485
 None
 0.81A 4q15A-2advC:
undetectable		 4q15A-2advC:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 GLU C 514
THR C 484
HIS C 485
 None
 0.81A 4q15B-2advC:
undetectable		 4q15B-2advC:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 SER C 122
ALA C 138
VAL C 137
 None
 0.65A 4x20C-2advC:
undetectable		 4x20C-2advC:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 8 LEU C 392
ALA C 316
LEU C 312
LEU C 309
ALA C 332
 None
 1.06A 4z90A-2advC:
undetectable
4z90B-2advC:
undetectable
4z90C-2advC:
undetectable
4z90D-2advC:
undetectable
4z90E-2advC:
undetectable		 4z90A-2advC:
21.65
4z90B-2advC:
21.65
4z90C-2advC:
21.65
4z90D-2advC:
21.65
4z90E-2advC:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 8 PRO C 379
PHE C 355
GLY C 365
ALA C 364
GLY C 362
 None
 1.29A 4zjzA-2advC:
undetectable		 4zjzA-2advC:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 8 PRO C 379
PHE C 355
GLY C 365
ALA C 364
GLY C 362
 None
 1.30A 4zjzB-2advC:
undetectable		 4zjzB-2advC:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 10 ALA C  48
GLU C  35
ARG C 499
HIS B  23
LEU B  24
 None
 1.26A 5dxbA-2advC:
undetectable		 5dxbA-2advC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 10 GLU C  35
ARG C 499
GLY C 454
HIS B  23
LEU B  24
 None
 1.40A 5dxbA-2advC:
undetectable		 5dxbA-2advC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 11 ALA C  48
GLU C  35
ARG C 499
HIS B  23
LEU B  24
 None
 1.22A 5dxgB-2advC:
undetectable		 5dxgB-2advC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 11 GLU C  35
LEU C 472
ARG C 499
GLY C 454
HIS B  23
 None
 1.25A 5dxgB-2advC:
undetectable		 5dxgB-2advC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 11 LEU C 432
GLU C 349
ARG C 353
GLY C 454
HIS B  23
 None
 1.25A 5dxgB-2advC:
undetectable		 5dxgB-2advC:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 7 VAL C 324
ALA C 328
VAL C 389
ARG C 393
 None
 0.81A 5fpdB-2advC:
undetectable		 5fpdB-2advC:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 10 ALA C  48
GLU C  35
ARG C 499
HIS B  23
LEU B  24
 None
 1.25A 5hyrA-2advC:
undetectable		 5hyrA-2advC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1;
Pseudomonas
sp.
SY-77-1) 		5 / 12 ALA B  16
LEU B  17
ALA B   5
THR C 187
PRO C 235
 None
 1.19A 5k9dA-2advB:
undetectable		 5k9dA-2advB:
7.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		3 / 3 GLU C 201
ARG C 217
TYR C 218
 None
 0.56A 5trqB-2advC:
undetectable		 5trqB-2advC:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 9 ALA C  48
GLU C  35
ARG C 499
HIS B  23
LEU B  24
 None
 1.23A 5wgqA-2advC:
undetectable		 5wgqA-2advC:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 9 GLU C  35
ARG C 499
GLY C 454
HIS B  23
LEU B  24
 None
 1.33A 5wgqA-2advC:
undetectable		 5wgqA-2advC:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		5 / 10 ALA C  48
GLU C  35
ARG C 499
HIS B  23
LEU B  24
 None
 1.24A 5wgqB-2advC:
undetectable		 5wgqB-2advC:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2adv GLUTARYL 7-
AMINOCEPHALOSPORANIC
ACID ACYLASE
(Pseudomonas
sp.
SY-77-1) 		4 / 5 ARG C 329
ALA C 328
GLN C 325
ILE C 318
 None
 1.37A 6f6sA-2advC:
undetectable
6f6sB-2advC:
undetectable		 6f6sA-2advC:
11.34
6f6sB-2advC:
9.96