SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aeg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		3 / 3 ASP A 185
VAL A 190
PRO A 128
 None
 0.73A 2avvA-2aegA:
undetectable		 2avvA-2aegA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		4 / 7 TYR A 179
HIS A  53
PRO A 121
TYR A  30
 None
 1.16A 2ombC-2aegA:
undetectable
2ombD-2aegA:
undetectable		 2ombC-2aegA:
23.30
2ombD-2aegA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		4 / 6 PRO A 192
ILE A 233
ASN A 187
LEU A 231
 None
 1.36A 2wekB-2aegA:
undetectable		 2wekB-2aegA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		3 / 3 TYR A  30
TYR A 179
ILE A  40
 None
 0.64A 3eteA-2aegA:
undetectable
3eteB-2aegA:
undetectable		 3eteA-2aegA:
19.05
3eteB-2aegA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		4 / 8 VAL A 120
VAL A 100
TYR A 179
ILE A 158
 None
 1.02A 3remA-2aegA:
undetectable		 3remA-2aegA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		4 / 8 VAL A 120
VAL A 100
TYR A 179
ILE A 158
 None
 1.02A 3remB-2aegA:
undetectable		 3remB-2aegA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 12 ARG A 167
GLY A 180
PHE A 155
ASN A  99
LEU A 178
 None
 0.97A 4aztA-2aegA:
undetectable		 4aztA-2aegA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		4 / 8 VAL A 160
TYR A 179
CYH A 118
ILE A 158
 None
 1.24A 4bqtC-2aegA:
undetectable
4bqtD-2aegA:
undetectable		 4bqtC-2aegA:
21.69
4bqtD-2aegA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 12 PHE A 154
PRO A 121
TYR A  30
GLY A  38
ILE A  24
 None
 1.07A 4kotA-2aegA:
undetectable		 4kotA-2aegA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 12 PHE A 154
PRO A 121
TYR A  30
GLY A  38
LEU A  51
 None
 1.49A 4kotA-2aegA:
undetectable		 4kotA-2aegA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 10 PHE A 154
PRO A 121
TYR A  30
GLY A  38
LEU A  51
 None
 1.45A 4kouA-2aegA:
0.0		 4kouA-2aegA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 12 PHE A 154
PRO A 121
TYR A  30
GLY A  38
LEU A  51
 None
 1.46A 4kowA-2aegA:
0.0		 4kowA-2aegA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		4 / 4 VAL A 120
ILE A 158
ASN A  99
VAL A 200
 None
 0.97A 5ajqA-2aegA:
undetectable		 5ajqA-2aegA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 9 ALA A 219
GLU A 218
MET A 212
GLY A 157
LEU A 182
 None
 1.43A 5wgqA-2aegA:
undetectable		 5wgqA-2aegA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2aeg HYPOTHETICAL PROTEIN
AGR_PAT_140
(Agrobacterium
fabrum) 		5 / 12 HIS A 116
GLY A 180
GLY A 157
ALA A 156
LEU A  58
 None
 1.19A 6b3bA-2aegA:
undetectable		 6b3bA-2aegA:
16.39