SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ag1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 LEU A  67
ALA A  57
ILE A  45
GLY A  24
VAL A  19
 None
 1.10A 1d4yA-2ag1A:
undetectable		 1d4yA-2ag1A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 8 ILE A 443
PHE A 524
LEU A 400
VAL A 389
 None
 0.87A 1fslA-2ag1A:
undetectable		 1fslA-2ag1A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 8 ILE A 443
PHE A 524
LEU A 400
VAL A 389
 None
 0.90A 1fslB-2ag1A:
undetectable		 1fslB-2ag1A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 9 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.38A 1gtnR-2ag1A:
undetectable
1gtnS-2ag1A:
undetectable		 1gtnR-2ag1A:
8.38
1gtnS-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 ILE A 292
PRO A 293
ARG A 206
ALA A 269
 None
 1.14A 1oniD-2ag1A:
undetectable
1oniE-2ag1A:
undetectable		 1oniD-2ag1A:
13.03
1oniE-2ag1A:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 424
HIS A  55
ASP A  91
HIS A 415
VAL A 390
 None
 1.50A 1qu3A-2ag1A:
undetectable		 1qu3A-2ag1A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 LEU A 158
LEU A  71
ALA A  70
LEU A  14
THR A 126
 None
 1.43A 1ya3A-2ag1A:
undetectable		 1ya3A-2ag1A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 LEU A 158
LEU A  71
ALA A  70
LEU A  14
THR A 126
 None
 1.44A 2aa5B-2ag1A:
undetectable		 2aa5B-2ag1A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 8 SER A 243
PHE A 412
ALA A 391
LEU A 400
 None
 1.16A 2bxkA-2ag1A:
undetectable		 2bxkA-2ag1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 11 LEU A 224
ALA A 237
LEU A 242
SER A 246
LEU A 248
 None
 1.34A 2c12F-2ag1A:
undetectable		 2c12F-2ag1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 ASN A 541
HIS A 505
ASN A 474
GLN A 476
 None
 1.12A 2hkkA-2ag1A:
undetectable		 2hkkA-2ag1A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 ASN A 475
GLY A 479
THR A 481
SER A 450
 MG  A 601 ( 2.8A)
TPP  A 602 (-2.9A)
TPP  A 602 ( 4.0A)
TPP  A 602 (-2.9A)
 1.23A 2o5yH-2ag1A:
undetectable
2o5yL-2ag1A:
undetectable		 2o5yH-2ag1A:
17.66
2o5yL-2ag1A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 8 LEU A 248
LEU A 274
VAL A 322
GLY A 323
 None
 0.95A 2po5B-2ag1A:
2.5		 2po5B-2ag1A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 VAL A 157
ALA A 145
PRO A 124
TRP A 128
 None
 1.04A 2q6oA-2ag1A:
2.2		 2q6oA-2ag1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		3 / 3 GLN A 118
THR A 111
TRP A 163
 None
 0.72A 2rctA-2ag1A:
undetectable		 2rctA-2ag1A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 11 GLU A   8
VAL A  19
GLY A   7
ILE A  33
VAL A  69
 None
 1.24A 2uxpB-2ag1A:
undetectable		 2uxpB-2ag1A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 LEU A 245
ALA A 215
LEU A 276
ALA A 278
 None
 0.94A 2vcvK-2ag1A:
undetectable		 2vcvK-2ag1A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 PHE A 458
GLY A 456
ALA A  52
PHE A 425
LEU A 444
 None
 1.33A 3a3yA-2ag1A:
2.0		 3a3yA-2ag1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 VAL A 142
LEU A  22
VAL A  19
VAL A  69
LEU A  98
 None
 1.02A 3gwxA-2ag1A:
undetectable		 3gwxA-2ag1A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 9 ALA A 145
VAL A 132
ILE A  33
LEU A 166
ILE A 138
 None
 1.28A 3jw3B-2ag1A:
undetectable		 3jw3B-2ag1A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		3 / 3 ASP A 448
ASN A 541
SER A 477
 MG  A 601 ( 2.4A)
None
TPP  A 602 ( 4.6A)
 0.97A 3lslA-2ag1A:
2.4
3lslD-2ag1A:
2.5		 3lslA-2ag1A:
18.36
3lslD-2ag1A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		3 / 3 SER A 477
ASP A 448
ASN A 541
 TPP  A 602 ( 4.6A)
MG  A 601 ( 2.4A)
None
 0.85A 3lslA-2ag1A:
undetectable
3lslD-2ag1A:
2.5		 3lslA-2ag1A:
18.36
3lslD-2ag1A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 8 PRO A 162
ILE A 165
MET A 133
ARG A 105
 None
 1.10A 3sfeB-2ag1A:
undetectable
3sfeC-2ag1A:
undetectable		 3sfeB-2ag1A:
17.99
3sfeC-2ag1A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 4 ASP A 304
ASP A 302
GLY A 309
THR A 284
 None
 1.34A 3tl9B-2ag1A:
undetectable		 3tl9B-2ag1A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 GLY A 422
VAL A 423
ASP A 392
THR A 446
 None
 1.13A 3vqrA-2ag1A:
undetectable		 3vqrA-2ag1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 5 GLY A 422
VAL A 423
ASP A 392
THR A 446
 None
 1.12A 3vqrB-2ag1A:
undetectable		 3vqrB-2ag1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 LEU A 224
LEU A 198
LEU A 201
ALA A 328
ALA A 332
 None
 1.00A 3vw7A-2ag1A:
undetectable		 3vw7A-2ag1A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 11 LEU A 274
VAL A 228
LEU A 224
LEU A 201
LEU A 276
 None
 1.24A 4or0B-2ag1A:
undetectable		 4or0B-2ag1A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 5 GLY A 393
THR A 446
HIS A 415
GLY A 422
 TPP  A 602 (-3.6A)
None
None
None
 1.01A 4v20A-2ag1A:
undetectable		 4v20A-2ag1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A  24
GLU A  50
LEU A 461
LEU A 468
ALA A 431
 None
 1.13A 4wcxC-2ag1A:
undetectable		 4wcxC-2ag1A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 LEU A 112
GLY A  76
GLY A  77
ALA A  74
 None
 0.61A 4yjiA-2ag1A:
undetectable		 4yjiA-2ag1A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 ASP A 107
ALA A 103
THR A 109
THR A 111
 None
 1.42A 4z4iA-2ag1A:
4.5		 4z4iA-2ag1A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 8 ALA A 431
VAL A 390
GLY A  59
ALA A  56
GLY A 426
 None
 0.93A 4zjzA-2ag1A:
3.1		 4zjzA-2ag1A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 8 ALA A 431
VAL A 390
GLY A  59
ALA A  56
GLY A 426
 None
 0.93A 4zjzB-2ag1A:
5.5		 4zjzB-2ag1A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A  54
GLY A  24
LEU A  71
ALA A  88
HIS A  55
 None
 1.02A 5c0oE-2ag1A:
undetectable		 5c0oE-2ag1A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 ALA A 215
SER A 216
ASP A 302
PRO A 303
 None
 1.12A 5c6pA-2ag1A:
undetectable		 5c6pA-2ag1A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 ALA A 134
THR A 135
VAL A 175
HIS A 137
 None
 1.24A 5ecnA-2ag1A:
undetectable		 5ecnA-2ag1A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5eeuS-2ag1A:
undetectable
5eeuT-2ag1A:
undetectable		 5eeuS-2ag1A:
8.38
5eeuT-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5eevS-2ag1A:
undetectable
5eevT-2ag1A:
undetectable		 5eevS-2ag1A:
8.38
5eevT-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5eewS-2ag1A:
undetectable
5eewT-2ag1A:
undetectable		 5eewS-2ag1A:
8.38
5eewT-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5eexS-2ag1A:
undetectable
5eexT-2ag1A:
undetectable		 5eexS-2ag1A:
8.38
5eexT-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5eeyS-2ag1A:
undetectable
5eeyT-2ag1A:
undetectable		 5eeyS-2ag1A:
8.38
5eeyT-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5eezS-2ag1A:
undetectable
5eezT-2ag1A:
undetectable		 5eezS-2ag1A:
8.38
5eezT-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5ef0S-2ag1A:
undetectable
5ef0T-2ag1A:
undetectable		 5ef0S-2ag1A:
8.38
5ef0T-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5ef1S-2ag1A:
undetectable
5ef1T-2ag1A:
undetectable		 5ef1S-2ag1A:
8.38
5ef1T-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5ef2S-2ag1A:
undetectable
5ef2T-2ag1A:
undetectable		 5ef2S-2ag1A:
8.38
5ef2T-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 10 GLY A  24
ALA A  56
HIS A  49
THR A  47
ILE A  45
 None
 1.36A 5ef3S-2ag1A:
undetectable
5ef3T-2ag1A:
undetectable		 5ef3S-2ag1A:
8.38
5ef3T-2ag1A:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 THR A 442
ASP A 435
GLY A  64
TYR A  60
 None
 1.09A 5hwaA-2ag1A:
undetectable		 5hwaA-2ag1A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		6 / 12 LEU A 461
PHE A 458
LEU A 468
ILE A 379
ALA A 531
LEU A 528
 None
 1.48A 5ienB-2ag1A:
undetectable		 5ienB-2ag1A:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGZ_A_SPRA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 9 LEU A 395
ILE A 549
HIS A 483
ARG A 356
VAL A 445
 TPP  A 602 (-3.4A)
None
None
None
None
 1.28A 5igzA-2ag1A:
undetectable		 5igzA-2ag1A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 VAL A 142
VAL A  19
ILE A  45
PHE A  23
 None
 1.00A 5jw1B-2ag1A:
undetectable		 5jw1B-2ag1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 8 THR A 135
GLN A 169
ILE A   4
GLY A   6
 None
 0.81A 5nzxA-2ag1A:
3.5		 5nzxA-2ag1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 7 THR A 135
GLN A 169
ILE A   4
GLY A   6
 None
 0.70A 5nzyA-2ag1A:
3.3		 5nzyA-2ag1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		4 / 6 PRO A 162
GLY A 100
LEU A 158
ARG A 131
 None
 0.95A 5x80A-2ag1A:
undetectable
5x80B-2ag1A:
undetectable		 5x80A-2ag1A:
16.28
5x80B-2ag1A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		3 / 3 GLY A 281
VAL A 210
MET A 275
 None
 0.48A 5ycpA-2ag1A:
undetectable		 5ycpA-2ag1A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 430
GLY A  59
ALA A  63
ILE A  45
PRO A  43
 None
 1.00A 6b3aA-2ag1A:
2.1		 6b3aA-2ag1A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 2ag1 BENZALDEHYDE LYASE
(Pseudomonas
fluorescens) 		5 / 12 GLY A 430
GLY A  59
ALA A  63
ILE A  45
PRO A  43
 None
 1.00A 6b3bA-2ag1A:
2.9		 6b3bA-2ag1A:
22.85