SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ah6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.40A 1p5zB-2ah6A:
undetectable		 1p5zB-2ah6A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 11 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.38A 1p62B-2ah6A:
0.1		 1p62B-2ah6A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.35A 2no0A-2ah6A:
undetectable		 2no0A-2ah6A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.35A 2no0B-2ah6A:
undetectable		 2no0B-2ah6A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.33A 2vppA-2ah6A:
0.2		 2vppA-2ah6A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.32A 2vppB-2ah6A:
undetectable		 2vppB-2ah6A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		6 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
ARG A  97
GLU A  58
 None
 1.39A 2zi9A-2ah6A:
1.5		 2zi9A-2ah6A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_1
(DEOXYCYTIDINE KINASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A  55
GLU A 104
TYR A 160
ARG A 171
GLU A  58
 None
 1.37A 2ziaA-2ah6A:
undetectable		 2ziaA-2ah6A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		4 / 8 ALA A  29
THR A  33
LEU A 154
LEU A 151
 None
 0.92A 4ejgB-2ah6A:
undetectable		 4ejgB-2ah6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		4 / 6 TYR A 160
GLU A  65
TYR A 153
LEU A 154
 None
 1.25A 4twdD-2ah6A:
3.6
4twdE-2ah6A:
4.3		 4twdD-2ah6A:
22.68
4twdE-2ah6A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		4 / 6 TYR A 160
GLU A  65
TYR A 153
LEU A 154
 None
 1.37A 4twdF-2ah6A:
undetectable
4twdG-2ah6A:
undetectable		 4twdF-2ah6A:
22.68
4twdG-2ah6A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		4 / 6 TYR A 160
GLU A  65
TYR A 153
LEU A 154
 None
 1.28A 4twdI-2ah6A:
undetectable
4twdJ-2ah6A:
undetectable		 4twdI-2ah6A:
22.68
4twdJ-2ah6A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_C_NCTC501_1
(AMINE OXIDASE)		 2ah6 BH1595, UNKNOWN
CONSERVED PROTEIN
(Bacillus
halodurans) 		5 / 10 LEU A 154
TYR A 153
GLU A  65
THR A  33
ALA A  86
 None
 1.35A 6c71C-2ah6A:
0.0		 6c71C-2ah6A:
19.51