SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ahn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		5 / 11 ALA A  53
ILE A   3
VAL A  13
LEU A  90
VAL A 106
 None
 1.07A 1rv7A-2ahnA:
undetectable
1rv7B-2ahnA:
undetectable		 1rv7A-2ahnA:
16.96
1rv7B-2ahnA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		5 / 10 ALA A  84
ALA A  70
THR A  55
LEU A 114
VAL A  13
 None
 1.41A 2wuzA-2ahnA:
undetectable		 2wuzA-2ahnA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		5 / 10 ALA A  84
ALA A  70
THR A  55
LEU A 114
VAL A  13
 None
 1.38A 2wuzB-2ahnA:
undetectable		 2wuzB-2ahnA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_B_SUZB201_1
(TRANSTHYRETIN)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		4 / 8 SER A 131
ALA A 217
SER A 117
THR A 119
 None
 0.56A 4ikjA-2ahnA:
2.7
4ikjB-2ahnA:
1.8		 4ikjA-2ahnA:
20.74
4ikjB-2ahnA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		4 / 8 ALA A 217
SER A 117
THR A 119
SER A 131
 None
 0.59A 4ikkA-2ahnA:
2.7
4ikkB-2ahnA:
undetectable		 4ikkA-2ahnA:
20.74
4ikkB-2ahnA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		5 / 12 GLY A 213
LEU A  41
PHE A  31
PHE A   5
GLY A  16
 None
 1.28A 5fsaB-2ahnA:
undetectable		 5fsaB-2ahnA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 2ahn THAUMATIN-LIKE
PROTEIN
(Prunus
avium) 		4 / 5 TYR A 216
GLN A 121
GLY A  98
ILE A  95
 None
 1.03A 6debB-2ahnA:
undetectable		 6debB-2ahnA:
16.84