SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ahw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.75A 1c9sI-2ahwA:
undetectable
1c9sJ-2ahwA:
undetectable		 1c9sI-2ahwA:
9.98
1c9sJ-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.76A 1c9sU-2ahwA:
undetectable
1c9sV-2ahwA:
undetectable		 1c9sU-2ahwA:
9.98
1c9sV-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.75A 1gtnA-2ahwA:
undetectable
1gtnK-2ahwA:
undetectable		 1gtnA-2ahwA:
9.98
1gtnK-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.78A 1gtnA-2ahwA:
undetectable
1gtnB-2ahwA:
undetectable		 1gtnA-2ahwA:
9.98
1gtnB-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.79A 1gtnC-2ahwA:
undetectable
1gtnD-2ahwA:
undetectable		 1gtnC-2ahwA:
9.98
1gtnD-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 6 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.79A 1gtnD-2ahwA:
undetectable
1gtnE-2ahwA:
undetectable		 1gtnD-2ahwA:
9.98
1gtnE-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.77A 1gtnE-2ahwA:
undetectable
1gtnF-2ahwA:
undetectable		 1gtnE-2ahwA:
9.98
1gtnF-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.75A 1gtnF-2ahwA:
undetectable
1gtnG-2ahwA:
undetectable		 1gtnF-2ahwA:
9.98
1gtnG-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 THR A 399
GLY A 152
THR A 143
ILE A 163
 None
 0.74A 1gtnJ-2ahwA:
undetectable
1gtnK-2ahwA:
undetectable		 1gtnJ-2ahwA:
9.98
1gtnK-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.72A 1gtnP-2ahwA:
undetectable
1gtnQ-2ahwA:
undetectable		 1gtnP-2ahwA:
9.98
1gtnQ-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 4 VAL A 373
ALA A 303
LEU A 526
PHE A 328
 None
 0.70A 1q97B-2ahwA:
undetectable		 1q97B-2ahwA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 4 SER A  80
ILE A  79
VAL A  88
THR A 158
 None
 1.22A 1u70A-2ahwA:
undetectable		 1u70A-2ahwA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 10 TYR A 375
ALA A 292
LEU A 516
GLY A 523
PHE A 524
 None
 0.87A 1uhoA-2ahwA:
undetectable		 1uhoA-2ahwA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.77A 1utdB-2ahwA:
undetectable
1utdC-2ahwA:
undetectable		 1utdB-2ahwA:
9.98
1utdC-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.76A 1utdF-2ahwA:
undetectable
1utdG-2ahwA:
undetectable		 1utdF-2ahwA:
9.98
1utdG-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.76A 1utdI-2ahwA:
undetectable
1utdJ-2ahwA:
undetectable		 1utdI-2ahwA:
9.98
1utdJ-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLY A 152
THR A 143
ILE A 163
THR A 399
 None
 0.77A 1utdJ-2ahwA:
undetectable
1utdK-2ahwA:
undetectable		 1utdJ-2ahwA:
9.98
1utdK-2ahwA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 SER A  67
GLU A  42
ASP A  73
 None
 0.77A 2avdB-2ahwA:
undetectable		 2avdB-2ahwA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 LEU A  31
ILE A 183
LEU A  46
ILE A  47
 None
 0.82A 2azxA-2ahwA:
undetectable		 2azxA-2ahwA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 THR A  48
THR A  45
ALA A  49
SER A  80
GLY A  78
 None
 1.20A 2f162-2ahwA:
undetectable		 2f162-2ahwA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 THR A  48
THR A  45
ALA A  49
SER A  80
GLY A  78
 None
 1.21A 2f16N-2ahwA:
undetectable		 2f16N-2ahwA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.68A 2j9dA-2ahwA:
0.0
2j9dB-2ahwA:
0.0
2j9dC-2ahwA:
0.0		 2j9dA-2ahwA:
13.94
2j9dB-2ahwA:
13.94
2j9dC-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.75A 2j9dA-2ahwA:
0.0
2j9dB-2ahwA:
0.0
2j9dC-2ahwA:
0.0		 2j9dA-2ahwA:
13.94
2j9dB-2ahwA:
13.94
2j9dC-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 LYS A 455
GLU A 459
ILE A 456
GLU A 172
ILE A 141
 None
 0.74A 2j9dA-2ahwA:
0.0
2j9dB-2ahwA:
0.0
2j9dC-2ahwA:
0.0		 2j9dA-2ahwA:
13.94
2j9dB-2ahwA:
13.94
2j9dC-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 10 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.74A 2j9dD-2ahwA:
0.0
2j9dE-2ahwA:
0.0
2j9dF-2ahwA:
0.0		 2j9dD-2ahwA:
13.94
2j9dE-2ahwA:
13.94
2j9dF-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 10 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.77A 2j9dD-2ahwA:
0.0
2j9dE-2ahwA:
0.0
2j9dF-2ahwA:
0.0		 2j9dD-2ahwA:
13.94
2j9dE-2ahwA:
13.94
2j9dF-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 10 LYS A 455
GLU A 459
ILE A 456
GLU A 172
ILE A 141
 None
 0.71A 2j9dD-2ahwA:
0.0
2j9dE-2ahwA:
0.0
2j9dF-2ahwA:
0.0		 2j9dD-2ahwA:
13.94
2j9dE-2ahwA:
13.94
2j9dF-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.74A 2j9dG-2ahwA:
0.0
2j9dH-2ahwA:
0.0
2j9dI-2ahwA:
0.0		 2j9dG-2ahwA:
13.94
2j9dH-2ahwA:
13.94
2j9dI-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.74A 2j9dG-2ahwA:
0.0
2j9dH-2ahwA:
0.0
2j9dI-2ahwA:
0.0		 2j9dG-2ahwA:
13.94
2j9dH-2ahwA:
13.94
2j9dI-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 LYS A 455
GLU A 459
ILE A 456
GLU A 172
ILE A 141
 None
 0.71A 2j9dG-2ahwA:
0.0
2j9dH-2ahwA:
0.0
2j9dI-2ahwA:
0.0		 2j9dG-2ahwA:
13.94
2j9dH-2ahwA:
13.94
2j9dI-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLU A 172
ILE A 141
LYS A 455
GLU A 459
 None
 0.78A 2j9dJ-2ahwA:
0.0
2j9dK-2ahwA:
0.0
2j9dL-2ahwA:
0.0		 2j9dJ-2ahwA:
13.94
2j9dK-2ahwA:
13.94
2j9dL-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 8 GLU A 172
ILE A 141
LYS A 455
GLU A 459
ILE A 456
 None
 0.80A 2j9dJ-2ahwA:
0.0
2j9dK-2ahwA:
0.0
2j9dL-2ahwA:
0.0		 2j9dJ-2ahwA:
13.94
2j9dK-2ahwA:
13.94
2j9dL-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 LYS A 455
GLU A 459
ILE A 456
GLU A 172
 None
 0.57A 2j9dJ-2ahwA:
0.0
2j9dK-2ahwA:
0.0
2j9dL-2ahwA:
0.0		 2j9dJ-2ahwA:
13.94
2j9dK-2ahwA:
13.94
2j9dL-2ahwA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 LEU A 462
ASP A 463
ILE A 413
ARG A 465
 None
 1.05A 2qqdA-2ahwA:
undetectable
2qqdE-2ahwA:
undetectable		 2qqdA-2ahwA:
7.31
2qqdE-2ahwA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 8 LEU A 206
ALA A  36
GLY A 335
GLY A 401
ASP A 404
 None
None
None
COA  A2600 ( 4.5A)
None
 1.37A 2yfxA-2ahwA:
undetectable		 2yfxA-2ahwA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 5 GLN A 362
THR A 334
THR A 399
LEU A 376
 None
None
None
COA  A2600 (-4.9A)
 1.35A 2zj0A-2ahwA:
2.1		 2zj0A-2ahwA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 GLY A 262
GLY A  39
GLN A 225
GLU A  42
THR A  45
 None
 1.13A 3ag3G-2ahwA:
0.0
3ag3N-2ahwA:
0.0
3ag3O-2ahwA:
0.0		 3ag3G-2ahwA:
10.23
3ag3N-2ahwA:
21.78
3ag3O-2ahwA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 VAL A  33
LEU A  34
GLY A  35
ILE A  40
THR A  44
 None
 1.26A 3bjwB-2ahwA:
undetectable		 3bjwB-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 VAL A 166
LYS A 164
ILE A 163
GLY A 152
 None
 0.83A 3bjwB-2ahwA:
undetectable		 3bjwB-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 VAL A  33
LEU A  34
GLY A  35
ILE A  40
THR A  44
 None
 1.25A 3bjwE-2ahwA:
undetectable		 3bjwE-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 VAL A  33
LEU A  34
GLY A  35
ILE A  40
THR A  44
 None
 1.23A 3bjwF-2ahwA:
undetectable		 3bjwF-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 VAL A  33
LEU A  34
GLY A  35
ILE A  40
SER A 257
 None
 1.19A 3bjwH-2ahwA:
undetectable		 3bjwH-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 VAL A  33
LEU A  34
GLY A  35
ILE A  40
THR A  44
 None
 1.25A 3bjwH-2ahwA:
undetectable		 3bjwH-2ahwA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 5 GLN A 362
THR A 334
THR A 399
LEU A 376
 None
None
None
COA  A2600 (-4.9A)
 1.36A 3ce6A-2ahwA:
undetectable		 3ce6A-2ahwA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 5 GLN A 362
THR A 334
THR A 399
LEU A 376
 None
None
None
COA  A2600 (-4.9A)
 1.37A 3ce6C-2ahwA:
undetectable		 3ce6C-2ahwA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 6 LEU A  41
ALA A  36
LEU A  34
THR A  69
 None
 1.03A 3cfqA-2ahwA:
undetectable		 3cfqA-2ahwA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 SER A 361
GLN A 362
PHE A 365
 None
 0.72A 3g4lC-2ahwA:
undetectable		 3g4lC-2ahwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 LEU A  34
ARG A 241
GLY A 335
PRO A 336
 None
 1.08A 3hcrA-2ahwA:
undetectable		 3hcrA-2ahwA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 ASP A 358
SER A 361
ARG A 126
 None
 0.89A 3loqA-2ahwA:
undetectable		 3loqA-2ahwA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 ASN A 306
THR A 451
GLY A 401
GLY A 400
SER A 406
 COA  A2600 ( 4.8A)
None
COA  A2600 ( 4.5A)
COA  A2600 ( 4.5A)
None
 1.02A 3nk7A-2ahwA:
undetectable		 3nk7A-2ahwA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 ILE A 315
VAL A 373
LEU A 462
ILE A 405
VAL A 387
 None
None
None
COA  A2600 (-4.6A)
None
 1.15A 3w67C-2ahwA:
undetectable		 3w67C-2ahwA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 ILE A 315
VAL A 373
LEU A 462
ILE A 405
VAL A 387
 None
None
None
COA  A2600 (-4.6A)
None
 1.14A 3w68B-2ahwA:
undetectable		 3w68B-2ahwA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 LEU A 105
ALA A  91
VAL A  33
ILE A 102
 None
 0.96A 3wsjB-2ahwA:
undetectable		 3wsjB-2ahwA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 PRO A 181
GLN A 123
THR A 122
LEU A 125
GLN A 132
 None
 1.42A 3zqeA-2ahwA:
0.0
3zqeB-2ahwA:
0.0		 3zqeA-2ahwA:
20.15
3zqeB-2ahwA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 GLN A 227
THR A 189
THR A 190
 None
 0.79A 4fu9A-2ahwA:
undetectable		 4fu9A-2ahwA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 GLN A 227
THR A 189
THR A 190
 None
 0.80A 4fufA-2ahwA:
undetectable		 4fufA-2ahwA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 6 LEU A  41
ALA A  36
LEU A  34
THR A  69
 None
 1.05A 4i89A-2ahwA:
undetectable		 4i89A-2ahwA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 10 ALA A  43
ILE A  47
VAL A  33
GLY A  35
ILE A  40
 None
 1.07A 4j5jB-2ahwA:
undetectable		 4j5jB-2ahwA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 ASP A 404
LEU A 371
VAL A 464
 None
 0.70A 4jecB-2ahwA:
undetectable		 4jecB-2ahwA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 TYR A 466
LEU A 462
VAL A 464
ILE A 412
LEU A 376
 None
None
None
None
COA  A2600 (-4.9A)
 1.44A 4k38A-2ahwA:
0.8
4k38D-2ahwA:
undetectable		 4k38A-2ahwA:
21.54
4k38D-2ahwA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 TYR A 466
LEU A 462
VAL A 464
ILE A 412
LEU A 376
 None
None
None
None
COA  A2600 (-4.9A)
 1.37A 4k38B-2ahwA:
1.2		 4k38B-2ahwA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 TYR A 466
LEU A 462
VAL A 464
ILE A 412
LEU A 376
 None
None
None
None
COA  A2600 (-4.9A)
 1.45A 4k39A-2ahwA:
undetectable		 4k39A-2ahwA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 ILE A  79
GLY A  37
ALA A  36
THR A  69
VAL A  33
 None
 0.96A 4nkxB-2ahwA:
undetectable		 4nkxB-2ahwA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 9 ALA A 325
VAL A 332
GLY A 339
THR A 341
VAL A 307
 None
 1.27A 4r20B-2ahwA:
undetectable		 4r20B-2ahwA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 GLY A  39
GLY A  38
GLY A  35
ALA A  36
ILE A 186
 None
 0.97A 4rtmA-2ahwA:
undetectable		 4rtmA-2ahwA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 ASP A  73
ARG A 101
PRO A 100
 None
 0.85A 4wanC-2ahwA:
undetectable		 4wanC-2ahwA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		6 / 10 ALA A  91
LEU A 154
ALA A 106
SER A  80
LEU A  82
ALA A  83
 None
 1.25A 4zbrA-2ahwA:
undetectable		 4zbrA-2ahwA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 5 PHE A 443
ASP A 500
PHE A 501
VAL A 381
 None
 1.19A 5a1rA-2ahwA:
undetectable		 5a1rA-2ahwA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 11 GLY A 262
GLY A  39
GLN A 225
GLU A  42
THR A  45
 None
 1.08A 5b1bG-2ahwA:
0.0
5b1bN-2ahwA:
0.0
5b1bO-2ahwA:
0.0		 5b1bG-2ahwA:
10.23
5b1bN-2ahwA:
21.78
5b1bO-2ahwA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 6 LEU A  41
ALA A  36
LEU A  34
THR A  69
 None
 1.08A 5bojA-2ahwA:
undetectable		 5bojA-2ahwA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 7 ILE A 311
GLY A 310
LEU A 447
PHE A 452
 COA  A2600 (-4.1A)
COA  A2600 (-3.1A)
None
None
 0.90A 5hieB-2ahwA:
undetectable		 5hieB-2ahwA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 LEU A 423
GLU A 469
THR A 468
ALA A 471
LEU A 491
 None
 1.33A 5ienA-2ahwA:
undetectable		 5ienA-2ahwA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		3 / 3 LYS A 164
ASP A 161
ILE A 141
 None
 0.70A 5kc4E-2ahwA:
undetectable		 5kc4E-2ahwA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 THR A  48
THR A  45
ALA A  49
SER A  80
GLY A  78
 None
 1.20A 5lf7V-2ahwA:
undetectable
5lf7b-2ahwA:
undetectable		 5lf7V-2ahwA:
19.17
5lf7b-2ahwA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 THR A  48
THR A  45
ALA A  49
SER A  80
GLY A  78
 None
 1.18A 5lf7H-2ahwA:
undetectable
5lf7N-2ahwA:
undetectable		 5lf7H-2ahwA:
19.17
5lf7N-2ahwA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 10 ILE A  40
GLY A  37
GLY A  72
VAL A  33
LEU A  34
 None
 1.04A 5o96C-2ahwA:
undetectable
5o96D-2ahwA:
undetectable		 5o96C-2ahwA:
18.75
5o96D-2ahwA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_1
(REGULATORY PROTEIN
TETR)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 GLN A 256
GLY A  39
ILE A  47
ASP A  73
 None
 1.02A 5vlmH-2ahwA:
0.0		 5vlmH-2ahwA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 ALA A 420
THR A 417
THR A 468
ALA A 312
 COA  A2600 ( 4.3A)
COA  A2600 ( 4.8A)
None
None
 1.03A 5x2tI-2ahwA:
undetectable
5x2tJ-2ahwA:
undetectable
5x2tK-2ahwA:
undetectable
5x2tL-2ahwA:
undetectable		 5x2tI-2ahwA:
13.49
5x2tJ-2ahwA:
15.20
5x2tK-2ahwA:
13.49
5x2tL-2ahwA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 6 GLN A 225
VAL A  15
LEU A  41
ARG A 241
 None
 1.16A 6brdB-2ahwA:
undetectable		 6brdB-2ahwA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		4 / 8 ALA A 292
VAL A 291
ARG A 293
ASP A 519
 None
 1.03A 6hu9a-2ahwA:
undetectable
6hu9e-2ahwA:
0.6		 6hu9a-2ahwA:
22.75
6hu9e-2ahwA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 2ahw PUTATIVE ENZYME YDIF
(Escherichia
coli) 		5 / 12 GLY A  39
LEU A 259
GLY A 261
ILE A  79
SER A 257
 None
 1.06A 6mhtA-2ahwA:
undetectable		 6mhtA-2ahwA:
20.15