SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aj2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 2aj2 HYPOTHETICAL UPF0301
PROTEIN VC0467
(Vibrio
cholerae) 		3 / 3 ALA A  54
VAL A  36
TRP A 179
 None
 0.82A 1c4dC-2aj2A:
undetectable
1c4dD-2aj2A:
undetectable		 1c4dC-2aj2A:
8.19
1c4dD-2aj2A:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 2aj2 HYPOTHETICAL UPF0301
PROTEIN VC0467
(Vibrio
cholerae) 		3 / 3 TRP A 179
ALA A  54
VAL A  36
 None
 0.90A 1c4dC-2aj2A:
undetectable
1c4dD-2aj2A:
undetectable		 1c4dC-2aj2A:
8.19
1c4dD-2aj2A:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 2aj2 HYPOTHETICAL UPF0301
PROTEIN VC0467
(Vibrio
cholerae) 		4 / 7 LEU A 128
GLU A 133
LEU A 125
ILE A 124
 None
 0.90A 3s56B-2aj2A:
undetectable		 3s56B-2aj2A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 2aj2 HYPOTHETICAL UPF0301
PROTEIN VC0467
(Vibrio
cholerae) 		3 / 3 SER A 159
PHE A  32
LYS A  33
 None
 0.82A 3u88A-2aj2A:
undetectable		 3u88A-2aj2A:
16.73