SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		4 / 8 ILE A  20
GLY A 123
LEU A  83
PHE A  94
 None
None
None
EDO  A 152 ( 4.0A)
 0.88A 2vctC-2aj7A:
undetectable		 2vctC-2aj7A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		4 / 6 GLY A 123
GLN A  82
ILE A 114
VAL A 115
 None
 1.15A 3kvvB-2aj7A:
undetectable		 3kvvB-2aj7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		4 / 6 GLY A 123
GLN A  82
ILE A 114
VAL A 115
 None
 1.13A 3kvvF-2aj7A:
undetectable		 3kvvF-2aj7A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		4 / 6 GLY A 123
GLN A  82
ILE A 114
VAL A 115
 None
 1.13A 4e1vF-2aj7A:
undetectable		 4e1vF-2aj7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		4 / 6 LEU A 139
SER A  66
PRO A  69
PHE A  65
 None
FMT  A 157 (-3.6A)
None
None
 0.99A 5b8iA-2aj7A:
undetectable		 5b8iA-2aj7A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		5 / 7 GLY A 123
LEU A  38
ILE A  26
GLY A  25
ILE A   4
 None
 1.02A 5vkqA-2aj7A:
undetectable
5vkqB-2aj7A:
undetectable		 5vkqA-2aj7A:
6.87
5vkqB-2aj7A:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		5 / 8 GLY A 123
LEU A  38
ILE A  26
GLY A  25
ILE A   4
 None
 1.04A 5vkqB-2aj7A:
undetectable
5vkqC-2aj7A:
undetectable		 5vkqB-2aj7A:
6.87
5vkqC-2aj7A:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2aj7 HYPOTHETICAL PROTEIN
BH3618
(Bacillus
halodurans) 		3 / 3 ARG A  18
PHE A  35
LEU A  38
 None
 0.69A 5x1bC-2aj7A:
undetectable		 5x1bC-2aj7A:
20.30