SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ajx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1RUK_H_BEZH601_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	2ajx	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 8	ALA H 34 TRP H 47 TYR H 50 GLY H 99	None	0.73A	1rukH-2ajxH: 28.7 1rukL-2ajxH: 15.0	1rukH-2ajxH: 80.82 1rukL-2ajxH: 26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2AJY_H_BEZH306_0 (ANTIBODY 7A1 FAB')	2ajx	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 4	ASN H 32 ALA H 34 ARG H 52 TYR H 97	None	0.87A	2ajyH-2ajxH: 32.2	2ajyH-2ajxH: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2AK1_H_BEZH401_0 (ANTIBODY 7A1 FAB')	2ajx	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 4	ASN H 32 ALA H 34 ARG H 52 TYR H 97	None	0.87A	2ak1H-2ajxH: 32.8	2ak1H-2ajxH: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NYA_A_JTZA1203_1 (BETA-2 ADRENERGIC RECEPTOR, LYSOZYME)	2ajx	ANTIBODY 7A1 FAB' (Mus musculus)	5 / 12	VAL H 171 VAL H 191 SER H 189 ASN H 209 ASN H 162	None	1.43A	3nyaA-2ajxH: undetectable	3nyaA-2ajxH: 17.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MTH_A_ACTA302_0 (ANTIBODY FAB HEAVY CHAIN)	2ajx	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 5	SER H 112 ALA H 114 PHE H 148 LEU H 178	None	0.24A	5mthA-2ajxH: 19.7	5mthA-2ajxH: 70.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RUK_H_BEZH601_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","2ajx","ANTIBODY 7A1 FAB'","Mus musculus",4,"ALA H  34;TRP H  47;TYR H  50;GLY H  99","None","0.73A","1rukH-2ajxH:28.7;1rukL-2ajxH:15.0","1rukH-2ajxH:80.82;1rukL-2ajxH:26.67"],["2AJY_H_BEZH306_0","ANTIBODY 7A1 FAB'","2ajx","ANTIBODY 7A1 FAB'","Mus musculus",4,"ASN H  32;ALA H  34;ARG H  52;TYR H  97","None","0.87A","2ajyH-2ajxH:32.2","2ajyH-2ajxH:100.00"],["2AK1_H_BEZH401_0","ANTIBODY 7A1 FAB'","2ajx","ANTIBODY 7A1 FAB'","Mus musculus",4,"ASN H  32;ALA H  34;ARG H  52;TYR H  97","None","0.87A","2ak1H-2ajxH:32.8","2ak1H-2ajxH:100.00"],["3NYA_A_JTZA1203_1","BETA-2 ADRENERGIC RECEPTOR, LYSOZYME","2ajx","ANTIBODY 7A1 FAB'","Mus musculus",5,"VAL H 171;VAL H 191;SER H 189;ASN H 209;ASN H 162","None","1.43A","3nyaA-2ajxH:undetectable","3nyaA-2ajxH:17.35"],["5MTH_A_ACTA302_0","ANTIBODY FAB HEAVY CHAIN","2ajx","ANTIBODY 7A1 FAB'","Mus musculus",4,"SER H 112;ALA H 114;PHE H 148;LEU H 178","None","0.24A","5mthA-2ajxH:19.7","5mthA-2ajxH:70.72"]]