SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ajz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZF_E_AZ1E2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 6J9-ZEU-DAR-ACA-DAR- NH2)	2ajz	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 7	GLY L 64 GLY L 66 SER L 67 LEU L 27	None	0.75A	5izfA-2ajzL: undetectable	5izfA-2ajzL: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9Y_A_ACTA409_0 (UNCHARACTERIZED PROTEIN KDOO)	2ajz	ANTIBODY 7A1 FAB' (Mus musculus)	3 / 3	LYS L 142 PRO L 141 LYS L 107	None	0.74A	5y9yA-2ajzL: undetectable	5y9yA-2ajzL: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_A_LLLA301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	2ajz	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 6	ASP L 143 TYR L 173 GLU L 105 GLU L 8	None	1.30A	6mn5A-2ajzL: undetectable	6mn5A-2ajzL: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_B_LLLB301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	2ajz	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 7	ASP L 143 TYR L 173 GLU L 105 GLU L 8	None	1.19A	6mn5B-2ajzL: undetectable	6mn5B-2ajzL: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN5_C_LLLC301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	2ajz	ANTIBODY 7A1 FAB' (Mus musculus)	4 / 6	ASP L 143 TYR L 173 GLU L 105 GLU L 8	None	1.28A	6mn5C-2ajzL: undetectable	6mn5C-2ajzL: 17.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5IZF_E_AZ1E2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;6J9-ZEU-DAR-ACA-DAR-NH2","2ajz","ANTIBODY 7A1 FAB'","Mus musculus",4,"GLY L  64;GLY L  66;SER L  67;LEU L  27","None","0.75A","5izfA-2ajzL:undetectable","5izfA-2ajzL:19.88"],["5Y9Y_A_ACTA409_0","UNCHARACTERIZED PROTEIN KDOO","2ajz","ANTIBODY 7A1 FAB'","Mus musculus",3,"LYS L 142;PRO L 141;LYS L 107","None","0.74A","5y9yA-2ajzL:undetectable","5y9yA-2ajzL:23.90"],["6MN5_A_LLLA301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","2ajz","ANTIBODY 7A1 FAB'","Mus musculus",4,"ASP L 143;TYR L 173;GLU L 105;GLU L   8","None","1.30A","6mn5A-2ajzL:undetectable","6mn5A-2ajzL:17.96"],["6MN5_B_LLLB301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","2ajz","ANTIBODY 7A1 FAB'","Mus musculus",4,"ASP L 143;TYR L 173;GLU L 105;GLU L   8","None","1.19A","6mn5B-2ajzL:undetectable","6mn5B-2ajzL:17.96"],["6MN5_C_LLLC301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","2ajz","ANTIBODY 7A1 FAB'","Mus musculus",4,"ASP L 143;TYR L 173;GLU L 105;GLU L   8","None","1.28A","6mn5C-2ajzL:undetectable","6mn5C-2ajzL:17.96"]]