SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2alb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_E_ACTE501_0 (RNA POLYMERASE 3D-POL)	2alb	PROTEIN DISULFIDE-ISOMERASE A3 (Homo sapiens)	4 / 4	CYH A 68 THR A 78 PHE A 28 LYS A 80	None	1.40A	4k50E-2albA: 0.0	4k50E-2albA: 13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_M_ACTM502_0 (RNA POLYMERASE 3D-POL)	2alb	PROTEIN DISULFIDE-ISOMERASE A3 (Homo sapiens)	4 / 4	CYH A 68 THR A 78 PHE A 28 LYS A 80	None	1.43A	4k50M-2albA: 0.0	4k50M-2albA: 13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB6_A_ADNA401_1 (ADENOSINE KINASE)	2alb	PROTEIN DISULFIDE-ISOMERASE A3 (Homo sapiens)	6 / 12	THR A 18 GLY A 22 VAL A 54 GLN A 107 GLY A 85 ILE A 81	None	1.21A	5kb6A-2albA: undetectable	5kb6A-2albA: 14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KB6_B_ADNB401_1 (ADENOSINE KINASE)	2alb	PROTEIN DISULFIDE-ISOMERASE A3 (Homo sapiens)	6 / 12	THR A 18 GLY A 22 VAL A 54 GLN A 107 GLY A 85 ILE A 81	None	1.18A	5kb6B-2albA: undetectable	5kb6B-2albA: 14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M0I_B_ACTB303_0 (SWI5-DEPENDENT HO EXPRESSION PROTEIN 2)	2alb	PROTEIN DISULFIDE-ISOMERASE A3 (Homo sapiens)	4 / 5	VAL A 59 THR A 67 ASN A 66 ASP A 8	None	1.35A	5m0iB-2albA: undetectable	5m0iB-2albA: 19.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4K50_E_ACTE501_0","RNA POLYMERASE 3D-POL","2alb","PROTEIN DISULFIDE-ISOMERASE A3","Homo sapiens",4,"CYH A  68;THR A  78;PHE A  28;LYS A  80","None","1.40A","4k50E-2albA:0.0","4k50E-2albA:13.86"],["4K50_M_ACTM502_0","RNA POLYMERASE 3D-POL","2alb","PROTEIN DISULFIDE-ISOMERASE A3","Homo sapiens",4,"CYH A  68;THR A  78;PHE A  28;LYS A  80","None","1.43A","4k50M-2albA:0.0","4k50M-2albA:13.86"],["5KB6_A_ADNA401_1","ADENOSINE KINASE","2alb","PROTEIN DISULFIDE-ISOMERASE A3","Homo sapiens",6,"THR A  18;GLY A  22;VAL A  54;GLN A 107;GLY A  85;ILE A  81","None","1.21A","5kb6A-2albA:undetectable","5kb6A-2albA:14.45"],["5KB6_B_ADNB401_1","ADENOSINE KINASE","2alb","PROTEIN DISULFIDE-ISOMERASE A3","Homo sapiens",6,"THR A  18;GLY A  22;VAL A  54;GLN A 107;GLY A  85;ILE A  81","None","1.18A","5kb6B-2albA:undetectable","5kb6B-2albA:14.45"],["5M0I_B_ACTB303_0","SWI5-DEPENDENT HO EXPRESSION PROTEIN 2","2alb","PROTEIN DISULFIDE-ISOMERASE A3","Homo sapiens",4,"VAL A  59;THR A  67;ASN A  66;ASP A   8","None","1.35A","5m0iB-2albA:undetectable","5m0iB-2albA:19.59"]]