SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ams'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 ASP A  10
VAL A   7
PRO A  65
 None
SO4  A  85 (-3.6A)
None
 0.53A 2avvA-2amsA:
undetectable		 2avvA-2amsA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  74
TRP A  78
 None
 1.14A 2xdcA-2amsA:
undetectable
2xdcB-2amsA:
undetectable		 2xdcA-2amsA:
10.96
2xdcB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  78
TRP A  74
 None
 1.23A 2xdcA-2amsA:
undetectable
2xdcB-2amsA:
undetectable		 2xdcA-2amsA:
10.96
2xdcB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 TRP A  74
VAL A  71
TRP A  78
 None
 1.22A 2xdcA-2amsA:
undetectable
2xdcB-2amsA:
undetectable		 2xdcA-2amsA:
10.96
2xdcB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 TRP A  78
VAL A  71
TRP A  74
 None
 1.14A 2xdcA-2amsA:
undetectable
2xdcB-2amsA:
undetectable		 2xdcA-2amsA:
10.96
2xdcB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  74
TRP A  78
 None
 1.16A 2y5mA-2amsA:
undetectable
2y5mB-2amsA:
undetectable		 2y5mA-2amsA:
10.96
2y5mB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  78
TRP A  74
 None
 1.25A 2y5mA-2amsA:
undetectable
2y5mB-2amsA:
undetectable		 2y5mA-2amsA:
10.96
2y5mB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  74
TRP A  78
 None
 1.15A 2y6nA-2amsA:
undetectable
2y6nB-2amsA:
undetectable		 2y6nA-2amsA:
10.96
2y6nB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  78
TRP A  74
 None
 1.25A 2y6nA-2amsA:
undetectable
2y6nB-2amsA:
undetectable		 2y6nA-2amsA:
10.96
2y6nB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 TRP A  74
VAL A  71
TRP A  78
 None
 1.26A 2y6nA-2amsA:
undetectable
2y6nB-2amsA:
undetectable		 2y6nA-2amsA:
10.96
2y6nB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 TRP A  78
VAL A  71
TRP A  74
 None
 1.14A 2y6nA-2amsA:
undetectable
2y6nB-2amsA:
undetectable		 2y6nA-2amsA:
10.96
2y6nB-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 VAL A  71
TRP A  74
TRP A  78
 None
 1.21A 3zq8A-2amsA:
undetectable
3zq8B-2amsA:
undetectable		 3zq8A-2amsA:
10.96
3zq8B-2amsA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2ams HIGH POTENTIAL
IRON-SULFUR PROTEIN
(Allochromatium
vinosum) 		3 / 3 ASP A  57
ASN A  70
ASP A  22
 None
 0.83A 5vopA-2amsA:
undetectable		 5vopA-2amsA:
12.46