SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2amx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		9 / 12 HIS A  55
HIS A  57
ASP A  59
PHE A 101
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.68A 1a4lA-2amxA:
39.8		 1a4lA-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
PHE A 328
PHE A 101
HIS A 266
ASP A 324
 CO  A1000 (-3.3A)
None
UNX  A2004 ( 4.8A)
None
None
 1.00A 1a4lA-2amxA:
39.8		 1a4lA-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A  59
HIS A  55
GLU A 288
ASP A 211
 CO  A1000 (-3.4A)
None
CO  A1000 (-3.3A)
None
None
 1.34A 1a4lA-2amxA:
39.8		 1a4lA-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		8 / 12 HIS A  57
ASP A  59
PHE A 101
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.72A 1a4lB-2amxA:
39.8		 1a4lB-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
LEU A 297
PHE A 101
HIS A 239
ASP A 324
 CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
CO  A1000 (-3.4A)
None
 1.41A 1a4lB-2amxA:
39.8		 1a4lB-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		9 / 12 HIS A  55
HIS A  57
ASP A  59
PHE A 101
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.64A 1a4lC-2amxA:
39.8		 1a4lC-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
PHE A 328
PHE A 101
HIS A 266
ASP A 324
 CO  A1000 (-3.3A)
None
UNX  A2004 ( 4.8A)
None
None
 0.97A 1a4lC-2amxA:
39.8		 1a4lC-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A  59
HIS A  55
GLU A 288
ASP A 211
 CO  A1000 (-3.4A)
None
CO  A1000 (-3.3A)
None
None
 1.30A 1a4lC-2amxA:
39.8		 1a4lC-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		7 / 12 HIS A  57
ASP A  59
GLY A 213
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
None
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.75A 1a4lD-2amxA:
39.9		 1a4lD-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		9 / 12 HIS A  57
ASP A  59
PHE A 101
GLY A 214
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.65A 1a4lD-2amxA:
39.9		 1a4lD-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
PHE A 328
PHE A 101
HIS A  55
ASP A 324
 CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
CO  A1000 (-3.3A)
None
 1.36A 1a4lD-2amxA:
39.9		 1a4lD-2amxA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 ASP A 323
HIS A  55
ILE A 183
HIS A 239
 CO  A1000 (-2.7A)
CO  A1000 (-3.3A)
None
CO  A1000 (-3.4A)
 1.01A 1ei6D-2amxA:
undetectable		 1ei6D-2amxA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 9 GLU A  94
GLY A  95
SER A 302
ASP A 304
THR A 305
 None
 1.12A 1m4gB-2amxA:
0.0		 1m4gB-2amxA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 11 GLU A 288
HIS A 239
GLY A 265
HIS A  57
PRO A 325
 None
CO  A1000 (-3.4A)
None
CO  A1000 (-3.2A)
None
 1.47A 1mjqA-2amxA:
undetectable
1mjqB-2amxA:
undetectable		 1mjqA-2amxA:
15.69
1mjqB-2amxA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 GLU A 128
TRP A 124
LYS A  96
 None
 0.95A 1qu2A-2amxA:
undetectable		 1qu2A-2amxA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.25A 1t69A-2amxA:
undetectable		 1t69A-2amxA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A 324
LEU A  60
ILE A 183
SER A 147
 CO  A1000 (-3.4A)
None
None
None
None
 1.28A 1xmuA-2amxA:
undetectable		 1xmuA-2amxA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A 324
LEU A  60
ILE A 183
SER A 147
 CO  A1000 (-3.4A)
None
None
None
None
 1.23A 1xoqA-2amxA:
undetectable		 1xoqA-2amxA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A 324
LEU A  60
ILE A 183
SER A 147
 CO  A1000 (-3.4A)
None
None
None
None
 1.26A 1xoqB-2amxA:
undetectable		 1xoqB-2amxA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 LEU A 297
HIS A  55
HIS A  57
GLY A 213
PHE A 328
 None
CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
None
None
 1.23A 1zz1B-2amxA:
undetectable
1zz1C-2amxA:
undetectable		 1zz1B-2amxA:
21.55
1zz1C-2amxA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 LEU A 287
ILE A 264
LEU A 276
ILE A 277
 None
 0.78A 2azxA-2amxA:
undetectable		 2azxA-2amxA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 7 LEU A 234
PRO A 143
ARG A 140
GLU A 155
 None
 0.96A 2jn3A-2amxA:
undetectable		 2jn3A-2amxA:
16.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
GLY A 213
GLU A 242
SER A 293
ASP A 323
 CO  A1000 (-3.3A)
None
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
 1.29A 2pgfA-2amxA:
56.9		 2pgfA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		8 / 12 HIS A  57
ASP A  59
GLY A 213
GLU A 242
HIS A 266
SER A 293
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
None
UNX  A2004 ( 4.8A)
None
None
CO  A1000 (-2.7A)
None
 0.89A 2pgfA-2amxA:
56.9		 2pgfA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		10 / 12 HIS A  57
ASP A  59
ILE A 183
GLY A 214
HIS A 239
GLU A 242
HIS A 266
SER A 293
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
None
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
None
CO  A1000 (-2.7A)
None
 0.32A 2pgfA-2amxA:
56.9		 2pgfA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		10 / 12 HIS A  57
ASP A  59
PHE A 101
ILE A 183
HIS A 239
GLU A 242
HIS A 266
SER A 293
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
None
CO  A1000 (-2.7A)
None
 0.44A 2pgfA-2amxA:
56.9		 2pgfA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		10 / 12 HIS A  55
HIS A  57
ASP A  59
ILE A 183
GLY A 214
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
None
None
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.29A 2pgrA-2amxA:
56.9		 2pgrA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		10 / 12 HIS A  55
HIS A  57
ASP A  59
PHE A 101
ILE A 183
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
None
UNX  A2004 ( 4.8A)
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.46A 2pgrA-2amxA:
56.9		 2pgrA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		7 / 12 HIS A  57
ASP A  59
GLY A 213
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
None
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.86A 2pgrA-2amxA:
56.9		 2pgrA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A  59
HIS A  55
GLU A 288
ASP A 211
 CO  A1000 (-3.4A)
None
CO  A1000 (-3.3A)
None
None
 1.15A 2pgrA-2amxA:
56.9		 2pgrA-2amxA:
69.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 LEU A  60
LEU A  98
PHE A 145
 None
 0.54A 2pgrA-2amxA:
56.9		 2pgrA-2amxA:
69.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 6 LEU A 276
VAL A 280
LYS A 281
ILE A 256
 None
 0.90A 2piwA-2amxA:
undetectable		 2piwA-2amxA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 HIS A 239
ASP A 211
ILE A 181
HIS A  57
 CO  A1000 (-3.4A)
None
None
CO  A1000 (-3.2A)
 0.93A 2xadA-2amxA:
undetectable		 2xadA-2amxA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 HIS A 239
ASP A 211
ILE A 181
HIS A  57
 CO  A1000 (-3.4A)
None
None
CO  A1000 (-3.2A)
 0.96A 2xadB-2amxA:
undetectable		 2xadB-2amxA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 HIS A 239
ASP A 211
ILE A 181
HIS A  57
 CO  A1000 (-3.4A)
None
None
CO  A1000 (-3.2A)
 0.97A 2xadC-2amxA:
undetectable		 2xadC-2amxA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 HIS A 239
ASP A 211
ILE A 181
HIS A  57
 CO  A1000 (-3.4A)
None
None
CO  A1000 (-3.2A)
 0.92A 2xadD-2amxA:
undetectable		 2xadD-2amxA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 5 HIS A  55
HIS A 239
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
CO  A1000 (-2.7A)
None
 1.19A 3c0zA-2amxA:
undetectable		 3c0zA-2amxA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 239
ASP A 324
LEU A  60
ILE A 183
SER A 147
 CO  A1000 (-3.4A)
None
None
None
None
 1.21A 3g4lD-2amxA:
undetectable		 3g4lD-2amxA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 6 HIS A 266
HIS A 239
HIS A  55
ASP A 324
 None
CO  A1000 (-3.4A)
CO  A1000 (-3.3A)
None
 0.78A 3nvcA-2amxA:
undetectable		 3nvcA-2amxA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 ILE A 292
ASP A 211
ILE A 181
ASP A 323
HIS A 239
 None
None
None
CO  A1000 (-2.7A)
CO  A1000 (-3.4A)
 1.33A 3phaD-2amxA:
4.8		 3phaD-2amxA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 HIS A 239
HIS A  55
HIS A  57
 CO  A1000 (-3.4A)
CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
 0.54A 3qpkA-2amxA:
undetectable		 3qpkA-2amxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 HIS A 239
HIS A  55
HIS A  57
 CO  A1000 (-3.4A)
CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
 0.55A 3qpkB-2amxA:
undetectable		 3qpkB-2amxA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 10 LEU A 180
ALA A 160
PHE A 161
GLY A 164
ILE A 165
 None
 1.23A 3qpsA-2amxA:
undetectable		 3qpsA-2amxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 HIS A 239
HIS A  55
HIS A 266
 CO  A1000 (-3.4A)
CO  A1000 (-3.3A)
None
 0.77A 3s3dA-2amxA:
undetectable		 3s3dA-2amxA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		6 / 12 HIS A 239
GLU A 242
GLU A 216
HIS A 266
SER A 293
ASP A 323
 CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
None
None
CO  A1000 (-2.7A)
 0.58A 4aqlA-2amxA:
3.8		 4aqlA-2amxA:
25.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 GLY A 214
ASP A 324
HIS A  57
ASP A 323
HIS A  55
 None
None
CO  A1000 (-3.2A)
CO  A1000 (-2.7A)
CO  A1000 (-3.3A)
 0.91A 4bz6C-2amxA:
undetectable		 4bz6C-2amxA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.22A 4bz6C-2amxA:
undetectable		 4bz6C-2amxA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 4 HIS A  55
HIS A  57
HIS A 266
HIS A 239
 CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
None
CO  A1000 (-3.4A)
 1.02A 4ef3A-2amxA:
undetectable		 4ef3A-2amxA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 203
LEU A 234
GLY A 209
PHE A 207
VAL A 229
 None
 1.21A 4fqsA-2amxA:
undetectable		 4fqsA-2amxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A 203
LEU A 234
GLY A 209
PHE A 207
VAL A 229
 None
 1.23A 4fqsB-2amxA:
undetectable		 4fqsB-2amxA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.21A 4lxzA-2amxA:
undetectable		 4lxzA-2amxA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.20A 4lxzC-2amxA:
undetectable		 4lxzC-2amxA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 6 ILE A 183
ASP A 211
GLY A 214
HIS A  55
 None
None
None
CO  A1000 (-3.3A)
 0.84A 4oltA-2amxA:
undetectable		 4oltA-2amxA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 6 ILE A 183
ASP A 211
GLY A 214
HIS A  55
 None
None
None
CO  A1000 (-3.3A)
 0.83A 4oltB-2amxA:
undetectable		 4oltB-2amxA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.30A 4qa0A-2amxA:
undetectable		 4qa0A-2amxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.26A 4qa2A-2amxA:
undetectable		 4qa2A-2amxA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
HIS A 239
HIS A 266
LEU A 297
ASP A 323
 CO  A1000 (-3.2A)
CO  A1000 (-3.4A)
None
None
CO  A1000 (-2.7A)
 0.33A 4r88A-2amxA:
16.7		 4r88A-2amxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
HIS A 239
GLU A 242
LEU A 297
ASP A 323
 CO  A1000 (-3.2A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
 0.33A 4r88B-2amxA:
22.0		 4r88B-2amxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
HIS A 239
GLU A 242
LEU A 297
ASP A 323
 CO  A1000 (-3.2A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
 0.34A 4r88C-2amxA:
21.7		 4r88C-2amxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
HIS A 239
GLU A 242
LEU A 297
ASP A 323
 CO  A1000 (-3.2A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
 0.33A 4r88D-2amxA:
19.2		 4r88D-2amxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
HIS A 239
GLU A 242
LEU A 297
ASP A 323
 CO  A1000 (-3.2A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
 0.34A 4r88E-2amxA:
21.7		 4r88E-2amxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  57
HIS A 239
GLU A 242
LEU A 297
ASP A 323
 CO  A1000 (-3.2A)
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
 0.34A 4r88F-2amxA:
22.0		 4r88F-2amxA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 5 LEU A 297
GLU A 100
LEU A  60
HIS A 239
 None
None
None
CO  A1000 (-3.4A)
 1.34A 4xi3B-2amxA:
undetectable		 4xi3B-2amxA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 LEU A  58
ASP A 324
ILE A 157
 None
 0.45A 4xi3D-2amxA:
undetectable		 4xi3D-2amxA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 ASP A 324
ASP A 323
GLU A 288
ASP A 211
 None
CO  A1000 (-2.7A)
None
None
 1.02A 4xjeA-2amxA:
undetectable		 4xjeA-2amxA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 7 VAL A 280
ILE A 285
LEU A 219
LEU A 259
 None
 1.02A 4xo7A-2amxA:
5.4		 4xo7A-2amxA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		4 / 8 ASP A 324
ASP A 323
GLU A 288
ASP A 211
 None
CO  A1000 (-2.7A)
None
None
 0.88A 5cfsA-2amxA:
undetectable		 5cfsA-2amxA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.26A 5eeiA-2amxA:
undetectable		 5eeiA-2amxA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 HIS A  55
HIS A 239
GLY A 213
ASP A 323
ASP A 324
 CO  A1000 (-3.3A)
CO  A1000 (-3.4A)
None
CO  A1000 (-2.7A)
None
 1.24A 5eeiB-2amxA:
undetectable		 5eeiB-2amxA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 HIS A 239
HIS A  55
HIS A  57
 CO  A1000 (-3.4A)
CO  A1000 (-3.3A)
CO  A1000 (-3.2A)
 0.49A 5migA-2amxA:
undetectable		 5migA-2amxA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		5 / 12 LEU A 180
ASP A 206
LEU A 371
ALA A 168
GLY A 164
 None
 1.09A 5uxdB-2amxA:
undetectable		 5uxdB-2amxA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		3 / 3 HIS A 239
HIS A  55
HIS A 266
 CO  A1000 (-3.4A)
CO  A1000 (-3.3A)
None
 0.72A 5x1bA-2amxA:
undetectable		 5x1bA-2amxA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		8 / 12 HIS A  57
ASP A  59
ILE A 183
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.29A 6n91A-2amxA:
40.0		 6n91A-2amxA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 2amx ADENOSINE DEAMINASE
(Plasmodium
yoelii) 		8 / 12 HIS A  57
ASP A  59
ILE A 183
HIS A 239
GLU A 242
HIS A 266
ASP A 323
ASP A 324
 CO  A1000 (-3.2A)
None
None
CO  A1000 (-3.4A)
UNX  A2004 ( 4.8A)
None
CO  A1000 (-2.7A)
None
 0.29A 6n91B-2amxA:
40.0		 6n91B-2amxA:
11.80