SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2anp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 7 ALA A 144
SER A 142
THR A  81
VAL A  79
 None
 1.00A 1dvxB-2anpA:
undetectable		 1dvxB-2anpA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 10 LEU A 178
LEU A 176
ILE A 143
THR A 126
ILE A 129
 None
 1.30A 1i18A-2anpA:
undetectable
1i18B-2anpA:
undetectable		 1i18A-2anpA:
19.56
1i18B-2anpA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 10 THR A 126
ILE A 129
LEU A 178
LEU A 176
ILE A 143
 None
 1.32A 1i18A-2anpA:
undetectable
1i18B-2anpA:
undetectable		 1i18A-2anpA:
19.56
1i18B-2anpA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 HIS A  70
ALA A 149
GLY A 157
GLU A 152
LEU A  98
 None
None
None
ZN  A 501 (-2.0A)
None
 1.25A 1mj2C-2anpA:
undetectable
1mj2D-2anpA:
undetectable		 1mj2C-2anpA:
13.99
1mj2D-2anpA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		3 / 3 VAL A  78
ALA A 147
HIS A  97
 None
None
ZN  A 502 (-3.3A)
 0.72A 1q23C-2anpA:
undetectable		 1q23C-2anpA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		3 / 3 VAL A  78
ALA A 147
HIS A  97
 None
None
ZN  A 502 (-3.3A)
 0.73A 1q23H-2anpA:
undetectable		 1q23H-2anpA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 ILE A 193
ASP A 195
TYR A 225
LEU A 155
TYR A 251
 None
 1.31A 2ya7C-2anpA:
undetectable		 2ya7C-2anpA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 ILE A 255
ASP A 260
ASP A 117
ASP A 118
LEU A 155
 None
None
ZN  A 501 ( 2.4A)
ZN  A 502 ( 4.9A)
None
 1.31A 2ya7C-2anpA:
undetectable		 2ya7C-2anpA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 6 ALA A 144
SER A 142
THR A  81
VAL A  79
 None
 1.00A 3d2tB-2anpA:
undetectable		 3d2tB-2anpA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 7 VAL A 125
THR A 126
ILE A  49
THR A  25
 None
 0.78A 3deuA-2anpA:
undetectable		 3deuA-2anpA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 7 ALA A 144
SER A 142
THR A  81
VAL A  79
 None
 0.96A 3ozkB-2anpA:
undetectable		 3ozkB-2anpA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 ALA A 231
ASN A 235
ASP A 117
ILE A 255
HIS A  97
 None
None
ZN  A 501 ( 2.4A)
None
ZN  A 502 (-3.3A)
 1.49A 3wemA-2anpA:
undetectable		 3wemA-2anpA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 ALA A 231
ASN A 235
ASP A 117
ILE A 255
HIS A  97
 None
None
ZN  A 501 ( 2.4A)
None
ZN  A 502 (-3.3A)
 1.47A 3weoA-2anpA:
undetectable		 3weoA-2anpA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 7 LEU A 155
TYR A 148
SER A 228
HIS A 230
 None
 1.02A 4arcA-2anpA:
undetectable		 4arcA-2anpA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 VAL A  10
LEU A  14
LEU A 208
ALA A 283
LEU A 280
 None
 1.02A 4o1zB-2anpA:
undetectable		 4o1zB-2anpA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PQA_A_X8ZA401_1
(SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		6 / 11 HIS A  97
ASP A 117
GLU A 152
ASN A 252
ILE A 255
HIS A 256
 ZN  A 502 (-3.3A)
ZN  A 501 ( 2.4A)
ZN  A 501 (-2.0A)
None
None
ZN  A 501 (-3.3A)
 1.43A 4pqaA-2anpA:
22.3		 4pqaA-2anpA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 5 HIS A 256
ASP A 229
ASP A 160
TYR A  73
 ZN  A 501 (-3.3A)
None
None
None
 0.97A 4qdjA-2anpA:
0.8		 4qdjA-2anpA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 4qvlV-2anpA:
undetectable
4qvlb-2anpA:
undetectable		 4qvlV-2anpA:
21.69
4qvlb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.37A 4qvlH-2anpA:
undetectable
4qvlN-2anpA:
undetectable		 4qvlH-2anpA:
21.69
4qvlN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.40A 4qvmV-2anpA:
undetectable
4qvmb-2anpA:
undetectable		 4qvmV-2anpA:
21.69
4qvmb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qvmH-2anpA:
undetectable
4qvmN-2anpA:
undetectable		 4qvmH-2anpA:
21.69
4qvmN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qvpV-2anpA:
undetectable
4qvpb-2anpA:
undetectable		 4qvpV-2anpA:
21.69
4qvpb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 4qvpH-2anpA:
undetectable
4qvpN-2anpA:
undetectable		 4qvpH-2anpA:
21.69
4qvpN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qvqV-2anpA:
undetectable
4qvqb-2anpA:
undetectable		 4qvqV-2anpA:
21.69
4qvqb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qvqH-2anpA:
undetectable
4qvqN-2anpA:
undetectable		 4qvqH-2anpA:
21.69
4qvqN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 10 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.40A 4qvvV-2anpA:
undetectable
4qvvb-2anpA:
0.0		 4qvvV-2anpA:
21.69
4qvvb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 10 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 4qvvH-2anpA:
undetectable
4qvvN-2anpA:
0.0		 4qvvH-2anpA:
21.69
4qvvN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qvwV-2anpA:
undetectable
4qvwb-2anpA:
undetectable		 4qvwV-2anpA:
21.69
4qvwb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qvwH-2anpA:
undetectable
4qvwN-2anpA:
undetectable		 4qvwH-2anpA:
21.69
4qvwN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.40A 4qw0V-2anpA:
undetectable
4qw0b-2anpA:
undetectable		 4qw0V-2anpA:
21.69
4qw0b-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qw0H-2anpA:
undetectable
4qw0N-2anpA:
undetectable		 4qw0H-2anpA:
21.69
4qw0N-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.37A 4qw1V-2anpA:
undetectable
4qw1b-2anpA:
undetectable		 4qw1V-2anpA:
21.69
4qw1b-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 4qw1H-2anpA:
undetectable
4qw1N-2anpA:
undetectable		 4qw1H-2anpA:
21.69
4qw1N-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 4qw3V-2anpA:
undetectable
4qw3b-2anpA:
undetectable		 4qw3V-2anpA:
21.69
4qw3b-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 4qw3H-2anpA:
undetectable
4qw3N-2anpA:
undetectable		 4qw3H-2anpA:
21.69
4qw3N-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 4qwuV-2anpA:
undetectable
4qwub-2anpA:
undetectable		 4qwuV-2anpA:
21.69
4qwub-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.37A 4qwuH-2anpA:
undetectable
4qwuN-2anpA:
undetectable		 4qwuH-2anpA:
21.69
4qwuN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 ALA A  87
GLY A 291
ALA A 283
MET A 286
GLY A 287
 None
 1.12A 4r29B-2anpA:
undetectable		 4r29B-2anpA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_B_3QBB203_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 TYR A 225
ASP A 229
ASP A 179
HIS A 151
PHE A 244
 None
None
ZN  A 502 (-2.0A)
ZN  A 502 (-4.2A)
None
 1.46A 4wh5A-2anpA:
0.1
4wh5B-2anpA:
0.1		 4wh5A-2anpA:
19.93
4wh5B-2anpA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		3 / 3 LEU A 205
ASP A 210
ILE A 193
 None
NA  A 503 ( 4.2A)
None
 0.59A 4xi3D-2anpA:
undetectable		 4xi3D-2anpA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 ALA A 175
SER A 174
VAL A 172
VAL A 128
TYR A 282
 None
 1.29A 4zj8A-2anpA:
undetectable		 4zj8A-2anpA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.32A 5bxnV-2anpA:
undetectable
5bxnb-2anpA:
undetectable		 5bxnV-2anpA:
22.03
5bxnb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.32A 5bxnH-2anpA:
undetectable
5bxnN-2anpA:
undetectable		 5bxnH-2anpA:
22.03
5bxnN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 9 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.40A 5cz7V-2anpA:
0.0
5cz7b-2anpA:
0.0		 5cz7V-2anpA:
21.69
5cz7b-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.40A 5cz7H-2anpA:
undetectable
5cz7N-2anpA:
undetectable		 5cz7H-2anpA:
21.69
5cz7N-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 5d0xV-2anpA:
undetectable
5d0xb-2anpA:
undetectable		 5d0xV-2anpA:
21.69
5d0xb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.39A 5d0xH-2anpA:
undetectable
5d0xN-2anpA:
undetectable		 5d0xH-2anpA:
21.69
5d0xN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 GLU A 245
ALA A 123
ALA A 124
VAL A 128
GLY A 269
 None
 0.89A 5igjA-2anpA:
undetectable		 5igjA-2anpA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 12 GLU A 245
ALA A 123
ALA A 124
VAL A 128
GLY A 269
 None
 0.88A 5igtA-2anpA:
undetectable		 5igtA-2anpA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 5l5fV-2anpA:
undetectable
5l5fb-2anpA:
0.0		 5l5fV-2anpA:
21.69
5l5fb-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 5l5fH-2anpA:
undetectable
5l5fN-2anpA:
0.0		 5l5fH-2anpA:
21.69
5l5fN-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.38A 5l66V-2anpA:
undetectable
5l66b-2anpA:
undetectable		 5l66V-2anpA:
21.69
5l66b-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		5 / 11 SER A 100
THR A 106
THR A  39
ALA A 112
THR A 258
 None
 1.36A 5l66H-2anpA:
undetectable
5l66N-2anpA:
undetectable		 5l66H-2anpA:
21.69
5l66N-2anpA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		3 / 3 HIS A  97
ASP A 229
HIS A 151
 ZN  A 502 (-3.3A)
None
ZN  A 502 (-4.2A)
 0.58A 5n1tW-2anpA:
undetectable		 5n1tW-2anpA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		3 / 3 HIS A 151
ASP A  99
HIS A  97
 ZN  A 502 (-4.2A)
None
ZN  A 502 (-3.3A)
 0.80A 5n1tW-2anpA:
undetectable		 5n1tW-2anpA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 4 SER A 228
THR A 181
ASP A 266
ASP A 117
 None
None
None
ZN  A 501 ( 2.4A)
 1.41A 5vimA-2anpA:
undetectable		 5vimA-2anpA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 4 SER A 228
THR A 181
ASP A 266
ASP A 117
 None
None
None
ZN  A 501 ( 2.4A)
 1.40A 5vimB-2anpA:
undetectable		 5vimB-2anpA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 6 TYR A 148
GLU A 152
GLY A  96
GLY A  95
 None
ZN  A 501 (-2.0A)
None
None
 0.90A 5x7pB-2anpA:
1.0		 5x7pB-2anpA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 2anp LEUCYL
AMINOPEPTIDASE
(Vibrio
proteolyticus) 		4 / 5 THR A 101
HIS A  97
ASP A 179
HIS A 151
 None
ZN  A 502 (-3.3A)
ZN  A 502 (-2.0A)
ZN  A 502 (-4.2A)
 1.42A 6dchA-2anpA:
undetectable		 6dchA-2anpA:
21.83