SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2aoq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		4 / 4 LEU A 207
PRO A 208
LEU A 209
ARG A 184
 None
 1.36A 1hrkB-2aoqA:
undetectable		 1hrkB-2aoqA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		3 / 3 PHE A 217
LEU A 154
LEU A 117
 None
 0.65A 1mx1E-2aoqA:
undetectable		 1mx1E-2aoqA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		4 / 5 GLY A  49
PRO A  41
VAL A  40
ILE A  38
 None
 0.94A 2aoiA-2aoqA:
undetectable		 2aoiA-2aoqA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		4 / 4 LEU A 207
PRO A 208
LEU A 209
ARG A 184
 None
 1.36A 2hrcB-2aoqA:
undetectable		 2hrcB-2aoqA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		4 / 6 HIS A  73
PHE A  71
GLY A  60
LYS A   9
 None
 1.14A 2i30A-2aoqA:
undetectable		 2i30A-2aoqA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		4 / 4 LEU A 207
PRO A 208
LEU A 209
ARG A 184
 None
 1.39A 2pnjB-2aoqA:
undetectable		 2pnjB-2aoqA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		5 / 10 GLN A 156
LEU A 117
VAL A 113
VAL A  95
LEU A 213
 None
 1.00A 3gwxA-2aoqA:
undetectable		 3gwxA-2aoqA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NV6_A_CAMA422_0
(CYTOCHROME P450)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		3 / 3 GLY A 105
ILE A 165
VAL A 166
 None
 0.47A 3nv6A-2aoqA:
undetectable		 3nv6A-2aoqA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2aoq DNA MISMATCH REPAIR
PROTEIN MUTH
(Haemophilus
influenzae) 		5 / 7 ILE A 197
LEU A 170
LEU A 183
VAL A 113
SER A 111
 None
 1.17A 3r9vA-2aoqA:
undetectable
3r9vB-2aoqA:
undetectable		 3r9vA-2aoqA:
23.40
3r9vB-2aoqA:
23.40