SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ap1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 8 SER A  84
ALA A  83
GLY A   9
ALA A  82
 None
 0.72A 1gtnI-2ap1A:
undetectable
1gtnJ-2ap1A:
undetectable		 1gtnI-2ap1A:
12.30
1gtnJ-2ap1A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A 139
GLY A 127
ASN A 107
GLY A 156
VAL A 244
 None
 1.07A 1jg4A-2ap1A:
undetectable		 1jg4A-2ap1A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 8 GLY A 193
GLY A 254
LEU A 255
ARG A 192
GLY A 131
 None
 1.41A 1jhqA-2ap1A:
undetectable		 1jhqA-2ap1A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 8 GLY A 193
PHE A 194
LEU A 255
ARG A 192
GLY A 131
 None
 1.45A 1jhqA-2ap1A:
undetectable		 1jhqA-2ap1A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 5 TRP A 115
PRO A 144
LEU A 299
GLY A  61
 None
 1.28A 1ya4C-2ap1A:
undetectable		 1ya4C-2ap1A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 11 ILE A 185
GLY A 133
GLU A 186
LEU A 233
GLY A 156
 None
 1.29A 2fn1A-2ap1A:
undetectable		 2fn1A-2ap1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 CYH A 179
CYH A 184
HIS A 157
 ZN  A 304 (-2.3A)
ZN  A 304 (-2.3A)
ZN  A 304 (-3.2A)
 0.76A 2iwkA-2ap1A:
undetectable		 2iwkA-2ap1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 CYH A 179
CYH A 184
HIS A 157
 ZN  A 304 (-2.3A)
ZN  A 304 (-2.3A)
ZN  A 304 (-3.2A)
 0.74A 2iwkB-2ap1A:
undetectable		 2iwkB-2ap1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 6 ALA A  50
ASP A  51
GLU A  49
MET A 293
 None
 1.15A 2ouzA-2ap1A:
undetectable		 2ouzA-2ap1A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.19A 2pxcA-2ap1A:
undetectable		 2pxcA-2ap1A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_A_TMQA611_1
(DHFR-TS)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 11 ALA A  42
ILE A  12
ILE A  64
PRO A  65
LEU A  75
 None
 0.90A 3clbA-2ap1A:
undetectable		 3clbA-2ap1A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 CYH A 179
CYH A 184
HIS A 157
 ZN  A 304 (-2.3A)
ZN  A 304 (-2.3A)
ZN  A 304 (-3.2A)
 0.70A 3dtuB-2ap1A:
undetectable		 3dtuB-2ap1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 CYH A 179
CYH A 184
HIS A 157
 ZN  A 304 (-2.3A)
ZN  A 304 (-2.3A)
ZN  A 304 (-3.2A)
 0.67A 3dtuD-2ap1A:
undetectable		 3dtuD-2ap1A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_A_TMQA611_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 10 ALA A  42
ILE A  12
ILE A  64
PRO A  65
LEU A  75
 None
 0.86A 3hbbA-2ap1A:
undetectable		 3hbbA-2ap1A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.20A 3p97A-2ap1A:
undetectable		 3p97A-2ap1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 PHE A 194
GLN A 204
PHE A 258
 None
 0.80A 3rv5A-2ap1A:
undetectable		 3rv5A-2ap1A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 TYR A  36
LEU A  96
VAL A  47
VAL A 100
CYH A  44
 None
 1.32A 3u9fB-2ap1A:
undetectable
3u9fC-2ap1A:
undetectable		 3u9fB-2ap1A:
20.92
3u9fC-2ap1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 TYR A  36
LEU A  96
VAL A  47
VAL A 100
CYH A  44
 None
 1.29A 3u9fH-2ap1A:
undetectable
3u9fI-2ap1A:
undetectable		 3u9fH-2ap1A:
20.92
3u9fI-2ap1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 TYR A  36
LEU A  96
VAL A  47
VAL A 100
CYH A  44
 None
 1.37A 3u9fJ-2ap1A:
undetectable
3u9fK-2ap1A:
undetectable		 3u9fJ-2ap1A:
20.92
3u9fK-2ap1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 CYH A  44
TYR A  36
LEU A  96
VAL A  47
VAL A 100
 None
 1.34A 3u9fP-2ap1A:
undetectable
3u9fS-2ap1A:
undetectable		 3u9fP-2ap1A:
20.92
3u9fS-2ap1A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 230
LEU A 233
LEU A 237
ILE A 282
PHE A 155
 None
 1.13A 4a7aB-2ap1A:
undetectable		 4a7aB-2ap1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.18A 4ctjA-2ap1A:
undetectable		 4ctjA-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.20A 4ctkA-2ap1A:
undetectable		 4ctkA-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 8 THR A 152
GLY A 137
ILE A 145
VAL A 139
PRO A 144
 None
 1.37A 4e1vC-2ap1A:
undetectable		 4e1vC-2ap1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 8 THR A 152
GLY A 137
ILE A 145
VAL A 139
PRO A 144
 None
 1.37A 4e1vD-2ap1A:
undetectable		 4e1vD-2ap1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 8 THR A 152
GLY A 137
ILE A 145
VAL A 139
PRO A 144
 None
 1.38A 4e1vG-2ap1A:
undetectable		 4e1vG-2ap1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 8 THR A 152
GLY A 137
ILE A 145
VAL A 139
PRO A 144
 None
 1.41A 4e1vH-2ap1A:
undetectable		 4e1vH-2ap1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A 241
LEU A 249
LEU A 128
ILE A 145
PHE A 155
 None
 1.04A 4odrA-2ap1A:
undetectable
4odrB-2ap1A:
undetectable		 4odrA-2ap1A:
16.41
4odrB-2ap1A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 GLU A 113
ALA A 114
PHE A 119
 None
 0.46A 4v1fA-2ap1A:
undetectable		 4v1fA-2ap1A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		3 / 3 GLU A 113
ALA A 114
PHE A 119
 None
 0.50A 4v1fC-2ap1A:
undetectable		 4v1fC-2ap1A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 6 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.14A 5bphA-2ap1A:
undetectable		 5bphA-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 7 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.17A 5bphB-2ap1A:
undetectable		 5bphB-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 4 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.13A 5bphC-2ap1A:
undetectable		 5bphC-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 6 TYR A 229
GLY A 254
SER A 256
LEU A 130
 None
 1.13A 5bphD-2ap1A:
undetectable		 5bphD-2ap1A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.18A 5e9qA-2ap1A:
undetectable		 5e9qA-2ap1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.18A 5ec8A-2ap1A:
undetectable		 5ec8A-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.18A 5ehgA-2ap1A:
undetectable		 5ehgA-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.18A 5eifA-2ap1A:
undetectable		 5eifA-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.20A 5eiwC-2ap1A:
undetectable		 5eiwC-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.17A 5ekxB-2ap1A:
undetectable		 5ekxB-2ap1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 291
GLY A   4
GLY A 295
ASP A   6
ILE A  12
 None
 0.89A 5ikmA-2ap1A:
undetectable		 5ikmA-2ap1A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 291
GLY A   4
GLY A 295
ASP A   6
ILE A  12
 None
 0.92A 5kqsA-2ap1A:
undetectable		 5kqsA-2ap1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 232
ALA A 164
LEU A 165
PHE A 172
ILE A 185
 None
 1.00A 5ljcA-2ap1A:
undetectable		 5ljcA-2ap1A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A  56
ASP A  51
ALA A   0
THR A 302
GLY A   4
 None
 0.89A 5m54E-2ap1A:
undetectable		 5m54E-2ap1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 291
GLY A   4
GLY A 295
ASP A   6
ILE A  12
 None
 0.93A 5njvC-2ap1A:
undetectable		 5njvC-2ap1A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 291
GLY A   4
GLY A 295
ASP A   6
ILE A  12
 None
 0.91A 5wz2A-2ap1A:
undetectable		 5wz2A-2ap1A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		6 / 12 GLY A 291
GLY A   4
GLY A 295
VAL A  43
ASP A   6
ILE A  12
 None
 1.20A 5wz2B-2ap1A:
undetectable		 5wz2B-2ap1A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 12 GLY A 291
GLY A   4
GLY A 295
ASP A   6
ILE A  12
 None
 0.92A 5wz2C-2ap1A:
undetectable		 5wz2C-2ap1A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		4 / 7 ILE A 282
LEU A 265
ARG A 278
LEU A 241
 None
 0.94A 5xdxA-2ap1A:
undetectable
5xdxJ-2ap1A:
undetectable		 5xdxA-2ap1A:
23.39
5xdxJ-2ap1A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 2ap1 PUTATIVE REGULATOR
PROTEIN
(Salmonella
enterica) 		5 / 10 LEU A  40
LEU A  14
PHE A  39
GLY A   4
VAL A  60
 None
 1.21A 6eu9B-2ap1A:
undetectable		 6eu9B-2ap1A:
11.95