SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2as5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 2as5 FORKHEAD BOX PROTEIN
P2
(Homo
sapiens) 		4 / 8 PHE F 538
LEU F 512
ILE F 517
THR F 537
 None
 0.86A 1sbrA-2as5F:
undetectable		 1sbrA-2as5F:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2as5 FORKHEAD BOX PROTEIN
P2
(Homo
sapiens) 		4 / 5 ALA F 510
TYR F 509
PRO F 506
PHE F 541
 None
 1.41A 4ze2A-2as5F:
2.1		 4ze2A-2as5F:
10.19