SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2asn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		3 / 3 ASP X  29
LEU X 122
LEU X 132
 None
IMD  X 202 ( 4.2A)
IMD  X 202 (-3.9A)
 0.33A 1ikeA-2asnX:
26.3		 1ikeA-2asnX:
47.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		3 / 3 ASP X  29
LEU X 122
LEU X 132
 None
IMD  X 202 ( 4.2A)
IMD  X 202 (-3.9A)
 0.34A 1np1B-2asnX:
27.0		 1np1B-2asnX:
46.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		5 / 12 PHE X 162
LEU X 106
VAL X 108
ALA X 155
HIS X 119
 None
 1.21A 1q23A-2asnX:
undetectable
1q23B-2asnX:
undetectable		 1q23A-2asnX:
20.09
1q23B-2asnX:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		4 / 8 PHE X  18
PHE X  42
ALA X 116
LEU X  12
 None
HEM  X 201 ( 4.0A)
None
None
 1.17A 1x8vA-2asnX:
undetectable		 1x8vA-2asnX:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		5 / 10 GLU X 124
GLY X 125
ASN X 102
TYR X  85
TYR X 104
 None
None
None
HEM  X 201 (-3.6A)
HEM  X 201 (-4.3A)
 1.24A 2h21A-2asnX:
undetectable		 2h21A-2asnX:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		5 / 11 GLU X 124
GLY X 125
ASN X 102
TYR X  85
TYR X 104
 None
None
None
HEM  X 201 (-3.6A)
HEM  X 201 (-4.3A)
 1.26A 2h21B-2asnX:
undetectable		 2h21B-2asnX:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		5 / 11 GLU X 124
GLY X 125
ASN X 102
TYR X  85
TYR X 104
 None
None
None
HEM  X 201 (-3.6A)
HEM  X 201 (-4.3A)
 1.35A 2h21C-2asnX:
undetectable		 2h21C-2asnX:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		3 / 3 SER X  65
TYR X  58
HIS X  57
 None
None
HEM  X 201 (-3.2A)
 0.70A 2r2vD-2asnX:
undetectable		 2r2vD-2asnX:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		3 / 3 LEU X  74
TYR X  81
GLN X  80
 None
 0.72A 2wekA-2asnX:
undetectable		 2wekA-2asnX:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		4 / 8 TYR X  58
ASN X  59
LYS X  63
LYS X  62
 None
 1.39A 3bjwD-2asnX:
undetectable		 3bjwD-2asnX:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		3 / 3 LYS X   9
SER X 150
GLN X 154
 None
 0.79A 3si7A-2asnX:
undetectable		 3si7A-2asnX:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		4 / 6 LEU X  79
LYS X   9
PRO X   8
GLU X 110
 None
 1.31A 4z4gA-2asnX:
undetectable		 4z4gA-2asnX:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_1_BEZ1801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2asn NITROPHORIN 2
(Rhodnius
prolixus) 		3 / 3 LEU X  55
PHE X 176
ILE X  69
 HEM  X 201 (-4.1A)
None
None
 0.63A 5dzk1-2asnX:
undetectable
5dzkF-2asnX:
undetectable
5dzkM-2asnX:
undetectable		 5dzk1-2asnX:
1.12
5dzkF-2asnX:
21.13
5dzkM-2asnX:
23.56