SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2atm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 6 PHE A  87
LYS A 170
LYS A 169
ALA A 168
 None
 1.11A 1hk2A-2atmA:
2.5		 1hk2A-2atmA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 8 SER A 248
ASN A 250
ILE A 247
GLY A 289
 None
 0.95A 1meiA-2atmA:
5.3		 1meiA-2atmA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 8 GLN A 215
LEU A 211
LEU A 218
ARG A 112
 None
 1.16A 2xn3A-2atmA:
undetectable
2xn3B-2atmA:
0.0		 2xn3A-2atmA:
20.44
2xn3B-2atmA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 5 LEU A  91
GLN A  43
THR A 164
HIS A  83
 None
 1.38A 2zj0C-2atmA:
undetectable		 2zj0C-2atmA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		5 / 12 ILE A 295
LEU A 319
ILE A 322
ALA A 323
THR A 327
 None
 1.06A 3a50A-2atmA:
undetectable		 3a50A-2atmA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		3 / 3 SER A  38
ASP A  45
ASN A  97
 None
 0.99A 3lsfB-2atmA:
undetectable
3lsfE-2atmA:
undetectable		 3lsfB-2atmA:
21.08
3lsfE-2atmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		3 / 3 ASP A  45
ASN A  97
SER A  38
 None
 1.02A 3lsfB-2atmA:
undetectable
3lsfE-2atmA:
undetectable		 3lsfB-2atmA:
21.08
3lsfE-2atmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		5 / 12 GLU A 243
ASN A 205
ASN A 187
TYR A 184
PHE A 186
 None
 1.41A 3mekA-2atmA:
undetectable		 3mekA-2atmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 7 PRO A  75
MET A 161
GLY A  54
PRO A  53
 None
 1.33A 3ucbB-2atmA:
undetectable		 3ucbB-2atmA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		5 / 12 TYR A 182
TRP A 210
ALA A 157
GLY A 178
ASP A 107
 None
None
None
None
MES  A 500 (-3.6A)
 1.39A 4iilA-2atmA:
undetectable		 4iilA-2atmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 7 GLU A 284
THR A 281
ASN A 187
SER A 259
 None
 1.10A 4pfjA-2atmA:
undetectable		 4pfjA-2atmA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 7 VAL A  14
TRP A  12
ILE A  34
LEU A 273
 None
 1.17A 4xo7B-2atmA:
2.7		 4xo7B-2atmA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V37_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		5 / 12 GLU A 243
ASN A 205
ASN A 187
TYR A 184
PHE A 186
 None
 1.42A 5v37A-2atmA:
undetectable		 5v37A-2atmA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 6 TYR A 184
ASP A 107
VAL A 105
GLU A 109
 None
MES  A 500 (-3.6A)
None
MES  A 500 (-3.6A)
 1.17A 6djzB-2atmA:
undetectable		 6djzB-2atmA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 2atm HYALURONOGLUCOSAMINI
DASE
(Vespula
vulgaris) 		4 / 7 ILE A  88
GLU A  55
HIS A  83
TRP A 177
 None
 1.14A 6j20A-2atmA:
undetectable		 6j20A-2atmA:
20.31